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Effect of vapor-phase glutaraldehyde crosslinking on electrospun starch fibers

Carbohydr Polym. 2016 Apr 20:140:356-61. doi: 10.1016/j.carbpol.2015.12.061. Epub 2015 Dec 29.

Abstract

In this work, we have proven that starch nanofibrous membranes with high tensile strength, water stability and non-cytotoxicity can be produced by electrospinning of starch solution and post-treatment with GTA in vapor phase. GTA vapor phase crosslinking plays a key role in forming water-stable nanofiber membrane and improving the mechanical properties. Comparing with non-crosslinked starch fibers, the crosslinked fibers are increased by nearly 10 times in tensile strength. The crosslinked starch fibrous membranes are non-cytotoxic. They may find applications in the fields of tissue engineering, pharmaceutical therapy and medical.

Keywords: Crosslinking; Electrospinning; Glutaraldehyde; Mechanical property; Starch fiber; Vapor phase.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology
  • Drug Stability
  • Electricity*
  • Escherichia coli / drug effects
  • Glutaral / chemistry*
  • Starch / chemistry*
  • Temperature
  • Tensile Strength
  • Volatilization
  • Water / chemistry

Substances

  • Anti-Bacterial Agents
  • Water
  • Starch
  • Glutaral