Abstract
We evaluated SARS-CoV-2 RNA and neutralising antibodies in blood donors (BD) residing in the Lodi Red Zone, Italy. Of 390 BDs recruited after 20 February 2020 - when the first COVID-19 case in Lombardy was identified, 91 (23%) aged 19-70 years were antibody positive. Viral RNA was detected in an additional 17 (4.3%) BDs, yielding ca 28% (108/390) with evidence of virus exposure. Five stored samples collected as early as 12 February were seropositive.
Keywords:
Lodi Red Zone; SARS-CoV-2 seroprevalence; epidemiology; microneutralization assay.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Adult
-
Aged
-
Antibodies, Neutralizing / immunology*
-
Betacoronavirus / immunology*
-
Blood Donors
-
COVID-19
-
COVID-19 Serotherapy
-
COVID-19 Testing
-
COVID-19 Vaccines
-
Clinical Laboratory Techniques
-
Coronavirus Infections / diagnosis
-
Coronavirus Infections / epidemiology*
-
Coronavirus Infections / immunology
-
Coronavirus Infections / therapy
-
Female
-
Humans
-
Immunization, Passive
-
Italy / epidemiology
-
Male
-
Middle Aged
-
Neutralization Tests
-
Pandemics
-
Pneumonia, Viral / epidemiology*
-
Pneumonia, Viral / immunology
-
Pneumonia, Viral / therapy
-
Prevalence
-
Real-Time Polymerase Chain Reaction
-
Reverse Transcriptase Polymerase Chain Reaction
-
SARS-CoV-2
-
Seroepidemiologic Studies
-
Young Adult
Substances
-
Antibodies, Neutralizing
-
COVID-19 Vaccines
-
Covid-19 aAPC vaccine