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Potential Sexual Transmission of Antifungal-Resistant Trichophyton indotineae

Emerg Infect Dis. 2024 Apr;30(4):807-809. doi: 10.3201/eid3004.240115. Epub 2024 Mar 4.

Abstract

We describe a case of tinea genitalis in an immunocompetent woman in Pennsylvania, USA. Infection was caused by Trichophyton indotineae potentially acquired through sexual contact. The fungus was resistant to terbinafine (first-line antifungal) but improved with itraconazole. Clinicians should be aware of T. indotineae as a potential cause of antifungal-resistant genital lesions.

Keywords: Pennsylvania; Trichophyton indotineae; United States; antifungal agents; antifungal resistance; antimicrobial resistance; antimicrobial stewardship; dermatomycoses; dermatophytes; fluconazole; fungi; itraconazole; sexually transmitted infections; terbinafine; tinea.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents* / pharmacology
  • Antifungal Agents* / therapeutic use
  • Drug Resistance, Fungal
  • Female
  • Humans
  • Itraconazole / therapeutic use
  • Microbial Sensitivity Tests
  • Terbinafine / pharmacology
  • Terbinafine / therapeutic use
  • Trichophyton*

Substances

  • Antifungal Agents
  • Itraconazole
  • Terbinafine

Supplementary concepts

  • Trichophyton indotineae