Although in the past century mortality in West Germany decreased similarly as in other
Western nations, these changes were less pronounced in East Germany. 1, 2 After German …

Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …

Previous genome-wide association studies (GWASs) of stroke — the second leading cause
of death worldwide — were conducted predominantly in populations of European ancestry 1 …

Study Design. A population-based cross-sectional multiregion postal survey. Objective. To
provide a descriptive epidemiology of the prevalence and severity of back pain in German …

In a genome-wide association study to identify loci associated with colorectal cancer (CRC)
risk, we genotyped 555,510 SNPs in 1,012 early-onset Scottish CRC cases and 1,012 …

With 12-month prevalence rates of more than 70%, back pain is currently one of the major
health problems for German adults and entails major economic consequences. The aim of this …

The relative risk (RR) and the odds ratio (OR) are the two most widely used measures of
association in epidemiology. The direct computation of relative risks is feasible if meaningful …

Asthma, hay fever (or allergic rhinitis) and eczema (or atopic dermatitis) often coexist in the
same individuals 1 , partly because of a shared genetic origin 2 , 3 , 4 . To identify shared risk …

Local and landscape-scale agricultural intensification is a major driver of global biodiversity
loss. Controversially discussed solutions include wildlife-friendly farming or combining high-…

Background It has been suggested that Crohn's disease (CD) is associated with an exaggerated
T-helper 1 cytokine response manifested by increased production of interleukin (IL)-12. …