User profiles for Erik Dassi

Erik Dassi

Department CIBIO, University of Trento
Verified email at unitn.it
Cited by 2631

Handshakes and fights: the regulatory interplay of RNA-binding proteins

E Dassi - Frontiers in molecular biosciences, 2017 - frontiersin.org
What drives the flow of signals controlling the outcome of post-transcriptional regulation of
gene expression? This regulatory layer, presiding to processes ranging from splicing to …

G-Quadruplexes in RNA biology: recent advances and future directions

L Dumas, P Herviou, E Dassi, A Cammas… - Trends in Biochemical …, 2021 - cell.com
RNA G-quadruplexes (RG4s) are four-stranded structures known to control gene expression
mechanisms, from transcription to protein synthesis, and DNA-related processes. Their …

The BioMart community portal: an innovative alternative to large, centralized data repositories

…, O Collin, R Cordova, RJ Cutts, E Dassi… - Nucleic acids …, 2015 - academic.oup.com
The BioMart Community Portal ( www.biomart.org ) is a community-driven effort to provide a
unified interface to biomedical databases that are distributed worldwide. The portal provides …

MODOMICS: a database of RNA modification pathways. 2021 update

…, G Avşar, A Romitelli, P Pir, E Dassi… - Nucleic acids …, 2022 - academic.oup.com
The MODOMICS database has been, since 2006, a manually curated and centralized
resource, storing and distributing comprehensive information about modified ribonucleosides. …

A mark of disease: how mRNA modifications shape genetic and acquired pathologies

…, S Torrini, P Pir, SG Conticello, F Aguilo, E Dassi - Rna, 2021 - rnajournal.cshlp.org
RNA modifications have recently emerged as a widespread and complex facet of gene
expression regulation. Counting more than 170 distinct chemical modifications with far-reaching …

AURA 2: Empowering discovery of post-transcriptional networks

E Dassi, A Re, S Leo, T Tebaldi, L Pasini, D Peroni… - …, 2014 - Taylor & Francis
Post-transcriptional regulation (PTR) of gene expression is now recognized as a major
determinant of cell phenotypes. The recent availability of methods to map protein-RNA …

Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila

…, MM Mulorz, T Lence, HH Wessels, E Dassi… - The EMBO …, 2021 - embopress.org
N6‐methyladenosine (m 6 A) regulates a variety of physiological processes through modulation
of RNA metabolism. This modification is particularly enriched in the nervous system of …

Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N6-Methyladenosine-Modified RNAs

…, L Alunno, R Belli, D Peroni, E Dassi… - ACS Pharmacology & …, 2022 - ACS Publications
YTHDF proteins bind the N 6 -methyladenosine (m6A)-modified mRNAs, influencing their
processing, stability, and translation. Therefore, the members of this protein family play crucial …

The architecture of the human RNA-binding protein regulatory network

A Quattrone, E Dassi - IScience, 2019 - cell.com
RNA-binding proteins (RBPs) are key players of post-transcriptional regulation of gene
expression, relying on competitive and cooperative interactions to fine-tune their action. Several …

hnRNP H/F drive RNA G-quadruplex-mediated translation linked to genomic instability and therapy resistance in glioblastoma

…, A Ameadan, F Guillonneau, E Dassi… - Nature …, 2020 - nature.com
RNA G-quadruplexes (RG4s) are four-stranded structures known to control mRNA translation
of cancer relevant genes. RG4 formation is pervasive in vitro but not in cellulo, indicating …