User profiles for Jianjun Chen

Jianjun Chen

- Verified email at coh.org - Cited by 23913

Jianjun Chen

- Verified email at ufl.edu - Cited by 12657

Jianjun Chen

- Verified email at bytedance.com - Cited by 2906

NiagaraCQ: A scalable continuous query system for internet databases

J Chen, DJ DeWitt, F Tian, Y Wang - Proceedings of the 2000 ACM …, 2000 - dl.acm.org
Continuous queries are persistent queries that allow users to receive new results when they
become available. While continuous query systems can transform a passive web into an …

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

…, M Wei, L Qu, JL Guan, C He, J Yang, J Chen - Nature cell …, 2018 - nature.com
N 6 -methyladenosine (m 6 A) is the most prevalent modification in eukaryotic messenger
RNAs (mRNAs) and is interpreted by its readers, such as YTH domain-containing proteins, to …

MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia

…, TR Golub, JD Rowley, J Chen - Proceedings of the …, 2007 - National Acad Sciences
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, whereas acute
myeloid leukemia (AML) is the most common acute leukemia in adults. In general, ALL has a …

METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis

…, Y Qing, X Qin, C Shen, M Xue, K Zhou, Z Chen… - Nature cell …, 2022 - nature.com
METTL16 has recently been identified as an RNA methyltransferase responsible for the
deposition of N 6 -methyladenosine (m 6 A) in a few transcripts. Whether METTL16 methylates a …

Biochar technology in wastewater treatment: A critical review

W Xiang, X Zhang, J Chen, W Zou, F He, X Hu… - Chemosphere, 2020 - Elsevier
Biochar is a promising agent for wastewater treatment, soil remediation, and gas storage and
separation. This review summarizes recent research development on biochar production …

RNA N6-methyladenosine modification in cancers: current status and perspectives

X Deng, R Su, H Weng, H Huang, Z Li, J Chen - Cell research, 2018 - nature.com
N 6 -methyladenosine (m 6 A), the most abundant internal modification in eukaryotic messenger
RNAs (mRNAs), has been shown to play critical roles in various normal bioprocesses …

FTO plays an oncogenic role in acute myeloid leukemia as a N6-methyladenosine RNA demethylase

…, Y Wang, GM Hong, H Huang, X Wang, P Chen… - Cancer cell, 2017 - cell.com
N 6 -Methyladenosine (m 6 A) represents the most prevalent internal modification in
mammalian mRNAs. Despite its functional importance in various fundamental bioprocesses, the …

[HTML][HTML] R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling

…, G Marcucci, X Jiang, JC Mulloy, J Jin, C He, J Chen - Cell, 2018 - cell.com
R-2-hydroxyglutarate (R-2HG), produced at high levels by mutant isocitrate dehydrogenase
1/2 (IDH1/2) enzymes, was reported as an oncometabolite. We show here that R-2HG also …

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations

…, S Mi, H Zhang, RT Luo, P Chen… - Proceedings of the …, 2008 - National Acad Sciences
MicroRNAs (miRNAs) are postulated to be important regulators in cancers. Here, we report
a genome-wide miRNA expression analysis in 52 acute myeloid leukemia (AML) samples …

METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification

…, JC Mulloy, J Yang, Z Qian, M Wei, C He, J Chen - Cell stem cell, 2018 - cell.com
N 6 -methyladenosine (m 6 A), the most prevalent internal modification in eukaryotic
messenger RNAs (mRNAs), plays critical roles in many bioprocesses. However, its functions in …