Coordinated regulation of acid resistance in Escherichia coli
…, S Jaini, A Lyubetskaya, K Hosur, JG Chiu… - BMC systems …, 2017 - Springer
Background Enteric Escherichia coli survives the highly acidic environment of the stomach
through multiple acid resistance (AR) mechanisms. The most effective system, AR2, …
through multiple acid resistance (AR) mechanisms. The most effective system, AR2, …
Algal chloroplast produced camelid VHH antitoxins are capable of neutralizing botulinum neurotoxin
DJ Barrera, JN Rosenberg, JG Chiu… - Plant biotechnology …, 2015 - Wiley Online Library
We have produced three antitoxins consisting of the variable domains of camelid heavy
chain‐only antibodies ( V H H ) by expressing the genes in the chloroplast of green algae. These …
chain‐only antibodies ( V H H ) by expressing the genes in the chloroplast of green algae. These …
Reversal of aging‐induced increases in aortic stiffness by targeting cytoskeletal protein‐protein interfaces
…, RJ Saphirstein, YZ Gao, Q Li, JG Chiu… - Journal of the …, 2018 - Am Heart Assoc
Background The proximal aorta normally functions as a critical shock absorber that protects
small downstream vessels from damage by pressure and flow pulsatility generated by the …
small downstream vessels from damage by pressure and flow pulsatility generated by the …
The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock
JC Chiu, JT Vanselow, A Kramer… - Genes & …, 2008 - genesdev.cshlp.org
A common feature of animal circadian clocks is the progressive phosphorylation of PERIOD
(PER) proteins, which is highly dependent on casein kinase Iδ/ε (CKIδ/ε; termed …
(PER) proteins, which is highly dependent on casein kinase Iδ/ε (CKIδ/ε; termed …
Development of a lipid-coated calcium phosphate nanoparticle for siRNA delivery to the brain
JG Chiu - 2020 - search.proquest.com
Glioblastoma multiforme (GBM) is the most common and lethal primary brain cancer, killing
approximately 17,000 patients in the US each year. Despite innovations in drugs and …
approximately 17,000 patients in the US each year. Despite innovations in drugs and …
SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
…, G Simmons, J Hackett Jr, MP Busch, CY Chiu - Nature …, 2020 - nature.com
Given the limited availability of serological testing to date, the seroprevalence of SARS-CoV-2-specific
antibodies in different populations has remained unclear. Here, we report very …
antibodies in different populations has remained unclear. Here, we report very …
O-GlcNAcylation of PERIOD regulates its interaction with CLOCK and timing of circadian transcriptional repression
…, JT Vanselow, H Zheng, A Schlosser, JC Chiu - PLoS …, 2019 - journals.plos.org
Circadian clocks coordinate time-of-day-specific metabolic and physiological processes to
maximize organismal performance and fitness. In addition to light and temperature, which are …
maximize organismal performance and fitness. In addition to light and temperature, which are …
[HTML][HTML] NEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speed
JC Chiu, HW Ko, I Edery - Cell, 2011 - cell.com
The speed of circadian clocks in animals is tightly linked to complex phosphorylation
programs that drive daily cycles in the levels of PERIOD (PER) proteins. Using Drosophila, we …
programs that drive daily cycles in the levels of PERIOD (PER) proteins. Using Drosophila, we …
[HTML][HTML] Alternative splicing of clock transcript mediates the response of circadian clocks to temperature changes
…, VH Lam, CA Tabuloc, H Zheng, C Zhao, JC Chiu - bioRxiv, 2024 - ncbi.nlm.nih.gov
… Created with BioRender.com licensed to the lab of JC Chiu. I. Western blots comparing CLK
… . Created with BioRender.com licensed to the lab of JC Chiu. BC. per-E-box-luciferase (per-…
… . Created with BioRender.com licensed to the lab of JC Chiu. BC. per-E-box-luciferase (per-…
CK1α collaborates with DOUBLETIME to regulate PERIOD function in the Drosophila circadian clock
…, KA Murphy, JS Diehl, RS Kwok, JC Chiu - Journal of …, 2018 - Soc Neuroscience
The animal circadian timing system interprets environmental time cues and internal
metabolic status to orchestrate circadian rhythms of physiology, allowing animals to perform …
metabolic status to orchestrate circadian rhythms of physiology, allowing animals to perform …