Cation‐free siRNA micelles as effective drug delivery platform and potent RNAi nanomedicines for glioblastoma therapy
T Jiang, Y Qiao, W Ruan, D Zhang, Q Yang… - Advanced …, 2021 - Wiley Online Library
Nanoparticle‐based small interfering RNA (siRNA) therapy shows great promise for
glioblastoma (GBM). However, charge associated toxicity and limited blood–brain‐barrier (BBB) …
glioblastoma (GBM). However, charge associated toxicity and limited blood–brain‐barrier (BBB) …
[HTML][HTML] Extreme wind speed distribution in a mixed wind climate
The meteorological services of mid-latitude countries record wind speeds averaged over 10
min or 1 h periods and peak wind speeds for the same averaging period or a full day. …
min or 1 h periods and peak wind speeds for the same averaging period or a full day. …
Improvement of formability and mechanical properties of magnesium alloys via pre-twinning: A review
Twinning can generate the change of texture and a large of twin boundaries, which can
greatly influence the mechanical properties of magnesium alloys. Thus, pre-twinning can be …
greatly influence the mechanical properties of magnesium alloys. Thus, pre-twinning can be …
Effects of facade rib arrangement on aerodynamic characteristics and flow structure of a square cylinder
Y Hui, J Liu, J Wang, Q Yang - Building and Environment, 2022 - Elsevier
Ribs on building façade can reduce wind loads acting on high-rise buildings and modify the
corresponding flow structures. The present study investigates the effect of vertical ribs with …
corresponding flow structures. The present study investigates the effect of vertical ribs with …
Non-stationary and non-Gaussian characteristics of wind speeds
Y Hui, B Li, H Kawai, Q Yang - Wind & structures, 2017 - dbpia.co.kr
Non-stationarity and non-Gaussian property are two of the most important characteristics of
wind. These two features are studied in this study based on wind speed records measured at …
wind. These two features are studied in this study based on wind speed records measured at …
A phosphorus-containing tertiary amine hardener enabled flame retardant, heat resistant and mechanically strong yet tough epoxy resins
Although current phosphorus (P)-based hardeners endowed epoxy resins (EPs) with intrinsic
flame retardancy, their addition usually reduced thermal and mechanical properties. In this …
flame retardancy, their addition usually reduced thermal and mechanical properties. In this …
Nano-scaled hydrophobic confinement of aqueous electrolyte by a nonionic amphiphilic polymer for long-lasting and wide-temperature Zn-based energy storage
Aqueous Zn-ion devices comprising a Zn-metal anode constitute an emerging class of next-generation
energy storage devices with the growing demand for renewable energies. Over …
energy storage devices with the growing demand for renewable energies. Over …
Blood-brain barrier–penetrating single CRISPR-Cas9 nanocapsules for effective and safe glioblastoma gene therapy
We designed a unique nanocapsule for efficient single CRISPR-Cas9 capsuling, noninvasive
brain delivery and tumor cell targeting, demonstrating an effective and safe strategy for …
brain delivery and tumor cell targeting, demonstrating an effective and safe strategy for …
Idelalisib: first-in-class PI3K delta inhibitor for the treatment of chronic lymphocytic leukemia, small lymphocytic leukemia, and follicular lymphoma
Q Yang, P Modi, T Newcomb, C Quéva, V Gandhi - Clinical cancer research, 2015 - AACR
Idelalisib [Zydelig (Gilead Sciences, Inc.), also known as CAL-101 and GS-1101] was approved
in 2014 in the United States and European Union for the treatment of three indolent B-…
in 2014 in the United States and European Union for the treatment of three indolent B-…
[HTML][HTML] The effects of orientation control via tension-compression on microstructural evolution and mechanical behavior of AZ31 Mg alloy sheet
The grain orientation control via twinning activity on deformation features is of great significance
to offer a key insight into understanding the deformation mechanism of Mg alloy sheets. …
to offer a key insight into understanding the deformation mechanism of Mg alloy sheets. …