Digitized images of full disk CaK spectroheliograms from two solar observatories were used to study cycle variation of ephemeral regions (ERs) over ten solar cycles 14-23. We calculate monthly averaged unsigned latitude of ERs and compare it with annual sunspot number. We find that average latitude of ERs can be used as a predictor for strength of solar cycle. For a short-term prediction (dT about 1-2 years), maximum latitude of ephemeral regions (in current cycle) defines the amplitude of that cycle (higher is the latitude of ERs, larger are the amplitudes of sunspot cycle). For a long-term prediction (dT about 1.5 solar cycles), latitude of ERs at declining phase of n-th cycle determines the amplitude of (n+2)-th sunspot cycle (lower is the latitude of ERs, stronger is the cycle). Using this latter dependency, we forecast the amplitude of sunspot cycle 24 at W=92 +/- 13 (in units of annual sunspot number).