All human diseases involve proteins, yet our current tools to characterize and quantify them
are limited. To better elucidate proteins across space, time, and molecular composition, we
provide a> 10 years of projection for technologies to meet the challenges that protein
biology presents. With a broad perspective, we discuss grand opportunities to transition the
science of proteomics into a more propulsive enterprise. Extrapolating recent trends, we
describe a next generation of approaches to define, quantify, and visualize the multiple …