Comparison of the predicted and observed secondary structure of T4 phage lysozyme
BW Matthews - Biochimica et Biophysica Acta (BBA)-Protein Structure, 1975 - Elsevier
Predictions of the secondary structure of T4 phage lysozyme, made by a number of
investigators on the basis of the amino acid sequence, are compared with the structure of
the protein determined experimentally by X-ray crystallography. Within the amino terminal
half of the molecule the locations of helices predicted by a number of methods agree
moderately well with the observed structure, however within the carboxyl half of the
molecule the overall agreement is poor. For eleven different helix predictions, the …
investigators on the basis of the amino acid sequence, are compared with the structure of
the protein determined experimentally by X-ray crystallography. Within the amino terminal
half of the molecule the locations of helices predicted by a number of methods agree
moderately well with the observed structure, however within the carboxyl half of the
molecule the overall agreement is poor. For eleven different helix predictions, the …
