The health benefits of regular exercise and the low participation rates combine to create a strong rationale for research into the determinants of this important health behavior. The purpose of the present study was to examine the relationship between personality and exercise behavior, motives, barriers and preferences. The five-factor model (FFM) of personality was selected to guide this investigation. Participants were 264 undergraduate students who completed a battery of self-administered questionnaires including the NEO Five-Factor Inventory (Costa & McCrae, 1992) and the Godin Leisure Time Exercise Questionnaire (Godin & Shephard, 1985). Consistent with hypotheses, the results of the study indicated that: It was concluded that the FFM may be a useful framework for understanding not only how much exercise people perform, but also their exercise motives, barriers, and preferences.