This article proposes an analytical framework to better understand the role that information and communication technology (ICT) skills play in improving employment opportunities for low-income groups. The paper draws upon research with over seventy non-governmental organizations (NGOs) that provide ICT training and other employment services in 30 countries around the world. It explores the linkage between ICT skills and employability on three levels: NGO program design, characteristics of individual job seekers or trainees, and environmental dynamics that influence employment outcomes. The researchers argue that basic ICT skills are often important, but are usually insufficient for members of disadvantaged groups to improve their employment situation. The proposed multilevel framework identifies some of the common elements that help situate basic ICT skills in relation to other factors that can facilitate or impede employability.