Health care and biomedicine are among the largest and most complex areas of human knowledge. All of us are potential patients and it is generally assumed that a long, healthy lifespan is an important and desirable component of quality of life. Information is at the heart of clinical practice and serves as the basis for therapeutic decisions. Biomedical information has important economic as well as personal implications, since most developed countries spend 8-15% of their economic output on health care with lesser amounts spent on biomedical research. Health care queries are also common for most search engines, and sites devoted to this area are among the most popular on the Web.