Transcriptional regulation and transpositional selection of active SINE sequences
C Schmid, R Maraia - Current opinion in genetics & development, 1992 - Elsevier
C Schmid, R Maraia
Current opinion in genetics & development, 1992•ElsevierAlu repeats are short interspersed elements whose transposition has lead to genetic
variability and heritable disorders in humans. A select subset of the nearly one million Alu
sequences in human DNA actually produce new transpositions. The evolution of newly
inserted Alu repeats is currently a key subject for study. Mechanisms of RNA polymerase III
activity and the sequence environment into which an Alu inserts might select for
transcriptional and posttranscriptional determinants of Alu transposition.
variability and heritable disorders in humans. A select subset of the nearly one million Alu
sequences in human DNA actually produce new transpositions. The evolution of newly
inserted Alu repeats is currently a key subject for study. Mechanisms of RNA polymerase III
activity and the sequence environment into which an Alu inserts might select for
transcriptional and posttranscriptional determinants of Alu transposition.
Alu repeats are short interspersed elements whose transposition has lead to genetic variability and heritable disorders in humans. A select subset of the nearly one million Alu sequences in human DNA actually produce new transpositions. The evolution of newly inserted Alu repeats is currently a key subject for study. Mechanisms of RNA polymerase III activity and the sequence environment into which an Alu inserts might select for transcriptional and posttranscriptional determinants of Alu transposition.
Elsevier