Accurate optic disc localization and segmentation are two main steps when designing automated screening systems for diabetic retinopathy. In this paper, a novel optic disc detection approach based on saliency object detection and modified local intensity clustering model is proposed. It consists of two stages: in the first stage, the saliency detection technique is introduced to the enhanced retinal image with the aim of locating the optic disc. In the second stage, the optic disc boundary is extracted by the modified Local Intensity Clustering (LIC) model with oval-shaped constrain. The performance of our proposed approach is tested on the public DIARETDB1 database. Compared to the state-of-the-art approaches, the experimental results show the advantages and effectiveness of the proposed approach.