Between objectivity and subjectivity.
C Branden, TA Jones - Nature, 1990 - search.ebscohost.com
C Branden, TA Jones
Nature, 1990•search.ebscohost.comBetween objectivity and subjectivity Page 1 LLGGLGGGLG Between objectivity and subjectivity
Carl-/var Brándén and T. Alwyn Jones Protein crystallography is an exacting trade, and the
results may contain errors that are difficult to identify. It is the crystallographer's responsibility to
make sure that incorrect protein structures do not reach the literature. STRUCTURAL knowledge
of biological macromolecules is essential for fully understanding their function as well as for
changing that function by protein engineering or drug design. There are two powerful …
Carl-/var Brándén and T. Alwyn Jones Protein crystallography is an exacting trade, and the
results may contain errors that are difficult to identify. It is the crystallographer's responsibility to
make sure that incorrect protein structures do not reach the literature. STRUCTURAL knowledge
of biological macromolecules is essential for fully understanding their function as well as for
changing that function by protein engineering or drug design. There are two powerful …
Abstract
Presents a commentary that explains some of the problems crystallographers face in interpreting their data. Technical developments; Crystallographic problems; Building a model; Removal of errors in the initial model; Assessment of the final model.
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