Iron (III) and ruthenium (II) porphyrin complex-catalyzed selective olefination of aldehydes with ethyl diazoacetate
Y Chen, L Huang, MA Ranade… - The Journal of Organic …, 2003 - ACS Publications
Y Chen, L Huang, MA Ranade, XP Zhang
The Journal of Organic Chemistry, 2003•ACS PublicationsThe commercially available Fe (III) and Ru (II) porphyrin complexes Fe (TPP) Cl and Ru
(TPP)(CO) are efficient catalysts for selective olefination of a variety of aldehydes with ethyl
diazoacetate in the presence of triphenylphosphine. The reactions were carried out under
mild conditions in a one-pot fashion with the use of a stoichiometrical amount of EDA, which
proceeded with excellent yields and high (E)-selectivity. Air atmosphere, low catalyst
loadings, and functional group tolerance were also demonstrated.
(TPP)(CO) are efficient catalysts for selective olefination of a variety of aldehydes with ethyl
diazoacetate in the presence of triphenylphosphine. The reactions were carried out under
mild conditions in a one-pot fashion with the use of a stoichiometrical amount of EDA, which
proceeded with excellent yields and high (E)-selectivity. Air atmosphere, low catalyst
loadings, and functional group tolerance were also demonstrated.
The commercially available Fe(III) and Ru(II) porphyrin complexes Fe(TPP)Cl and Ru(TPP)(CO) are efficient catalysts for selective olefination of a variety of aldehydes with ethyl diazoacetate in the presence of triphenylphosphine. The reactions were carried out under mild conditions in a one-pot fashion with the use of a stoichiometrical amount of EDA, which proceeded with excellent yields and high (E)-selectivity. Air atmosphere, low catalyst loadings, and functional group tolerance were also demonstrated.
ACS Publications