Abstract: Acute tubular necrosis was induced by experimental gentamicin nephrotoxicity to follow ... more Abstract: Acute tubular necrosis was induced by experimental gentamicin nephrotoxicity to follow and describe the changes in ultrasonographic appearance of the kidney. Sonograms were evaluated for information on size, shape and renal structure, specifically including ...
Sunnary: S ix non-lactating, non-pregnant adult ewes divided into two groups of 3 animal each as ... more Sunnary: S ix non-lactating, non-pregnant adult ewes divided into two groups of 3 animal each as a control and experimental groups were u sed to evaluate the effect of phlorhizin-induced ketosis on plasma and rumen fluid riboflavin and niacin concentrations. The me an pH value s ' and the counts of protozoa and bacteria of the rumen f/uid in experimental group di d not change significantly (p>0.05). Alteration of plasma riboflavin concentration in experimental group w as not significant (p>O. 05). Whereas both plasma and rumen fluid niacin concentrations decreased from 5. 03 mc gl ml and 9. 53 mcg!ml to 2.39 mcglml and 2.41 mcglml respectively and decraements in both plasma and rumen fluid niacin concentrations were significant (p 0.05). Bununla birlikte plazma ve rumen SlVlSI niasin konsantrasyonlan s~raswta 5. 03 ve 9.53 mcg!ml'den 2.39 ve 2.41 mcglml'ye dustu ve bu dususler onemliydi (p<0.05). Introduction For years, lt was commonly accepted knowledge that ru...
This study investigated the pharmacokinetics of pentoxifylline (PTX) and its 5-hydroxyhexyl metab... more This study investigated the pharmacokinetics of pentoxifylline (PTX) and its 5-hydroxyhexyl metabolite (M-I) after single-dose intravenous (IV) administration (10 mg/kg) of PTX in six healthy cattle. The safety of PTX was evaluated by clinical observation and biochemical analysis. Plasma concentrations of PTX and M-I were simultaneously determined by reverse-phase high performance liquid chromatography. Pharmacokinetic parameters were calculated using non-compartmental methods. Salivation and discomfort were observed for 2 h following the drug administration. Serum direct bilirubin, total bilirubin, and phosphorus levels at 24 h following the drug administration were significantly different from the control values (0 h) (P < 0.05). Pharmacokinetic variables of PTX were characterized by a short terminal elimination half-life (1.05 ± 0.19 h), a large volume of distribution (6.30 ± 1.76 L/kg), and high total body clearance (5.31 ± 1.27 L/h/kg). The mean ratio between the area under ...
Bu olgu sunumunda, 5 yasli Ingiliz Pointer irki bir kopekte Demodex canis kokenli atipik dermatit... more Bu olgu sunumunda, 5 yasli Ingiliz Pointer irki bir kopekte Demodex canis kokenli atipik dermatitisin teshisi ve tedavisi degerlendirildi. Klinik, laboratuvar, bakteriyolojik, parazitolojik ve histopatolojik muayeneler isiginda, deri kazintisi ve deri biyopsisi orneklerinden Demodex canis, β-hemolitik Staphylococcus aureus ve Microsporum canis izole ve identifiye edilen bu olgu, atipik dermatitis olarak tanimlandi. Banyo uygulamasi (ketokonazol ve benzoxyl peroxide sampuan, haftada 2 kez), ivermektin (0.6 mg/kg, SC, 3 gun ara ile, 4 ay), sefaperazonsulbaktam kombinasyonu (22 mg/kg, 10 gun), cefquinom (2 mg/kg, IM, 3.5 ay) ve ketokonazol (10 mg/kg, oral, 4 ay) ile dort ay boyunca tedavi edildi. Sonuc olarak, Demodex canis kokenli atipik dermatitis olgularinda tedavi suresinin uzun tutulmasi gerektigi ve 3 gunluk araliklarla yapilan ivermektin tedavisinin basarili oldugu ve herhangi bir komplikasyona neden olmadigi degerlendirildi.
Tropical animal health and production, Jan 15, 2018
This study investigated the pharmacokinetics of pentoxifylline (PTX) and its 5-hydroxyhexyl metab... more This study investigated the pharmacokinetics of pentoxifylline (PTX) and its 5-hydroxyhexyl metabolite (M-I) after single-dose intravenous (IV) administration (10 mg/kg) of PTX in six healthy cattle. The safety of PTX was evaluated by clinical observation and biochemical analysis. Plasma concentrations of PTX and M-I were simultaneously determined by reverse-phase high performance liquid chromatography. Pharmacokinetic parameters were calculated using non-compartmental methods. Salivation and discomfort were observed for 2 h following the drug administration. Serum direct bilirubin, total bilirubin, and phosphorus levels at 24 h following the drug administration were significantly different from the control values (0 h) (P < 0.05). Pharmacokinetic variables of PTX were characterized by a short terminal elimination half-life (1.05 ± 0.19 h), a large volume of distribution (6.30 ± 1.76 L/kg), and high total body clearance (5.31 ± 1.27 L/h/kg). The mean ratio between the area under ...
Evaluation of The Dynamic (Overground) Endoscopy Procedure in The Diagnosis of Upper Respiratory ... more Evaluation of The Dynamic (Overground) Endoscopy Procedure in The Diagnosis of Upper Respiratory Tract Diseases Affecting Performance of Racehorses In this study, efficiencies of dynamic (overground) and resting endoscopic examinations were compared in dynamic upper respiratory tract problems which are a cause of poor performance in race horses. Thirty actively-racing horses which were brought to Turkey Jokey Club Racehorses Hospital with poor performance and abnormal respiratory tract sounds were examined while running and rest. The diagnostic effectiveness of dynamic endoscopy and resting endoscopy procedures were compared for the diagnosis of dynamic obstructions of the upper respiratory tract. Dynamic pharyngeal collapse (DPC) in 5 race horses, third or fourth degree of left laryngeal hemiplegia (LLH) in 3 race horses, second degree of axial deviation of aryepiglottic folds (ADAF) in 3 racehorses, rostral displacement of the palatopharyngeal arch (RDPA) in 1 racehorse, and dorsa...
Abstract: Acute tubular necrosis was induced by experimental gentamicin nephrotoxicity to follow ... more Abstract: Acute tubular necrosis was induced by experimental gentamicin nephrotoxicity to follow and describe the changes in ultrasonographic appearance of the kidney. Sonograms were evaluated for information on size, shape and renal structure, specifically including ...
Sunnary: S ix non-lactating, non-pregnant adult ewes divided into two groups of 3 animal each as ... more Sunnary: S ix non-lactating, non-pregnant adult ewes divided into two groups of 3 animal each as a control and experimental groups were u sed to evaluate the effect of phlorhizin-induced ketosis on plasma and rumen fluid riboflavin and niacin concentrations. The me an pH value s ' and the counts of protozoa and bacteria of the rumen f/uid in experimental group di d not change significantly (p>0.05). Alteration of plasma riboflavin concentration in experimental group w as not significant (p>O. 05). Whereas both plasma and rumen fluid niacin concentrations decreased from 5. 03 mc gl ml and 9. 53 mcg!ml to 2.39 mcglml and 2.41 mcglml respectively and decraements in both plasma and rumen fluid niacin concentrations were significant (p 0.05). Bununla birlikte plazma ve rumen SlVlSI niasin konsantrasyonlan s~raswta 5. 03 ve 9.53 mcg!ml'den 2.39 ve 2.41 mcglml'ye dustu ve bu dususler onemliydi (p<0.05). Introduction For years, lt was commonly accepted knowledge that ru...
This study investigated the pharmacokinetics of pentoxifylline (PTX) and its 5-hydroxyhexyl metab... more This study investigated the pharmacokinetics of pentoxifylline (PTX) and its 5-hydroxyhexyl metabolite (M-I) after single-dose intravenous (IV) administration (10 mg/kg) of PTX in six healthy cattle. The safety of PTX was evaluated by clinical observation and biochemical analysis. Plasma concentrations of PTX and M-I were simultaneously determined by reverse-phase high performance liquid chromatography. Pharmacokinetic parameters were calculated using non-compartmental methods. Salivation and discomfort were observed for 2 h following the drug administration. Serum direct bilirubin, total bilirubin, and phosphorus levels at 24 h following the drug administration were significantly different from the control values (0 h) (P < 0.05). Pharmacokinetic variables of PTX were characterized by a short terminal elimination half-life (1.05 ± 0.19 h), a large volume of distribution (6.30 ± 1.76 L/kg), and high total body clearance (5.31 ± 1.27 L/h/kg). The mean ratio between the area under ...
Bu olgu sunumunda, 5 yasli Ingiliz Pointer irki bir kopekte Demodex canis kokenli atipik dermatit... more Bu olgu sunumunda, 5 yasli Ingiliz Pointer irki bir kopekte Demodex canis kokenli atipik dermatitisin teshisi ve tedavisi degerlendirildi. Klinik, laboratuvar, bakteriyolojik, parazitolojik ve histopatolojik muayeneler isiginda, deri kazintisi ve deri biyopsisi orneklerinden Demodex canis, β-hemolitik Staphylococcus aureus ve Microsporum canis izole ve identifiye edilen bu olgu, atipik dermatitis olarak tanimlandi. Banyo uygulamasi (ketokonazol ve benzoxyl peroxide sampuan, haftada 2 kez), ivermektin (0.6 mg/kg, SC, 3 gun ara ile, 4 ay), sefaperazonsulbaktam kombinasyonu (22 mg/kg, 10 gun), cefquinom (2 mg/kg, IM, 3.5 ay) ve ketokonazol (10 mg/kg, oral, 4 ay) ile dort ay boyunca tedavi edildi. Sonuc olarak, Demodex canis kokenli atipik dermatitis olgularinda tedavi suresinin uzun tutulmasi gerektigi ve 3 gunluk araliklarla yapilan ivermektin tedavisinin basarili oldugu ve herhangi bir komplikasyona neden olmadigi degerlendirildi.
Tropical animal health and production, Jan 15, 2018
This study investigated the pharmacokinetics of pentoxifylline (PTX) and its 5-hydroxyhexyl metab... more This study investigated the pharmacokinetics of pentoxifylline (PTX) and its 5-hydroxyhexyl metabolite (M-I) after single-dose intravenous (IV) administration (10 mg/kg) of PTX in six healthy cattle. The safety of PTX was evaluated by clinical observation and biochemical analysis. Plasma concentrations of PTX and M-I were simultaneously determined by reverse-phase high performance liquid chromatography. Pharmacokinetic parameters were calculated using non-compartmental methods. Salivation and discomfort were observed for 2 h following the drug administration. Serum direct bilirubin, total bilirubin, and phosphorus levels at 24 h following the drug administration were significantly different from the control values (0 h) (P < 0.05). Pharmacokinetic variables of PTX were characterized by a short terminal elimination half-life (1.05 ± 0.19 h), a large volume of distribution (6.30 ± 1.76 L/kg), and high total body clearance (5.31 ± 1.27 L/h/kg). The mean ratio between the area under ...
Evaluation of The Dynamic (Overground) Endoscopy Procedure in The Diagnosis of Upper Respiratory ... more Evaluation of The Dynamic (Overground) Endoscopy Procedure in The Diagnosis of Upper Respiratory Tract Diseases Affecting Performance of Racehorses In this study, efficiencies of dynamic (overground) and resting endoscopic examinations were compared in dynamic upper respiratory tract problems which are a cause of poor performance in race horses. Thirty actively-racing horses which were brought to Turkey Jokey Club Racehorses Hospital with poor performance and abnormal respiratory tract sounds were examined while running and rest. The diagnostic effectiveness of dynamic endoscopy and resting endoscopy procedures were compared for the diagnosis of dynamic obstructions of the upper respiratory tract. Dynamic pharyngeal collapse (DPC) in 5 race horses, third or fourth degree of left laryngeal hemiplegia (LLH) in 3 race horses, second degree of axial deviation of aryepiglottic folds (ADAF) in 3 racehorses, rostral displacement of the palatopharyngeal arch (RDPA) in 1 racehorse, and dorsa...
Uploads