Faklofen (fosfonobaklofen) je selektivni antagonist GABAB receptora.[3]
Faklofen
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IUPAC ime
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[3-amino-2-(4-hlorofenil)propil]fosforna kiselina |
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Identifikacija
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CAS registarski broj
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108351-35-5
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PubChem[1][2]
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1641
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IUPHAR ligand
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1091
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Jmol-3D slike
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Slika 1
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C1=CC(=CC=C1C(CN)CP(=O)(O)O)Cl |
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InChI=1S/C9H13ClNO3P/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H2,12,13,14) Y Kod: VSGNGLJPOGUDON-UHFFFAOYSA-N Y |
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Svojstva
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Molekulska formula
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C9H13ClNO3P
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Molarna masa
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249,631 g/mol
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Y (šta je ovo?)
(verifikuj)
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
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Infobox references
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- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ David I.B. KerrCorresponding author contact information, Jennifer Ong, Rolf H. Prager, Bruce D. Gynther, David R. Curtis (1987-03-03). „Phaclofen: a peripheral and central baclofen antagonist”. Brain Research 405: 150–154.