Allele frequencies for the 15 short tandem repeats loci D8S1179, D21S11, D7S820, CSF1PO, D3S1358,... more Allele frequencies for the 15 short tandem repeats loci D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA (AmpFℓSTR® Identifiler™ PCR Amplification Kit, Applied Biosystems) were determined in a sample of 322 unrelated individuals from Nicaragua. Statistical analyses were performed using PowerStats v12 and Genepop v4.0. All loci are in Hardy–Weinberg equilibrium and show high discrimination for paternity analysis and forensic genetic applications.
Trypanosoma cruzi is the etiologic agent of Chagas&am... more Trypanosoma cruzi is the etiologic agent of Chagas' disease, a chronic inflammatory condition that results in heart and digestive complications. The first draft of the parasite genome is now complete and it is expected that, along with the published genomic and proteomic analyses discussed herein, it will lead to the identification of crucial genes and proteins directly associated with disease. This article reviews the current research trends addressing host-parasite interaction, parasite genetic variability and diagnosis. These advances will certainly bring about major developments not only in our understanding of Trypanosoma cruzi biology, but also in the application of new technologies to disease prevention and control.
Allele frequencies for the 15 short tandem repeats loci D8S1179, D21S11, D7S820, CSF1PO, D3S1358,... more Allele frequencies for the 15 short tandem repeats loci D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA (AmpFℓSTR® Identifiler™ PCR Amplification Kit, Applied Biosystems) were determined in a sample of 322 unrelated individuals from Nicaragua. Statistical analyses were performed using PowerStats v12 and Genepop v4.0. All loci are in Hardy–Weinberg equilibrium and show high discrimination for paternity analysis and forensic genetic applications.
Trypanosoma cruzi is the etiologic agent of Chagas&am... more Trypanosoma cruzi is the etiologic agent of Chagas' disease, a chronic inflammatory condition that results in heart and digestive complications. The first draft of the parasite genome is now complete and it is expected that, along with the published genomic and proteomic analyses discussed herein, it will lead to the identification of crucial genes and proteins directly associated with disease. This article reviews the current research trends addressing host-parasite interaction, parasite genetic variability and diagnosis. These advances will certainly bring about major developments not only in our understanding of Trypanosoma cruzi biology, but also in the application of new technologies to disease prevention and control.
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Papers by Jorge Huete