ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Alkynes, when carrying an α-sulfonyl group, are shown to be stereoselectively reduced to z-alkene... more Alkynes, when carrying an α-sulfonyl group, are shown to be stereoselectively reduced to z-alkenes using sodium borohydride under mildly basic conditions.
Phosphorus Sulfur and Silicon and The Related Elements, 1991
Phosphorus, Sulfur, and Silicon, 1991, Vol. 57. pp. 17-23 Reprints available directly from the pu... more Phosphorus, Sulfur, and Silicon, 1991, Vol. 57. pp. 17-23 Reprints available directly from the publisher Photocopying permitted by license only 0 1991 Gordon and Breach Science Publishen SA Printed in the United Kingdom ... ANIONIC ADDITIONS TO CONJUGATED ENYNES- ...
Journal of The Chemical Society, Chemical Communications, 1990
Reaction of sodium benzenesulphinate with I ,2-di(4-chlorobenzenesulphonyl)hex-2-en-4-yne affords... more Reaction of sodium benzenesulphinate with I ,2-di(4-chlorobenzenesulphonyl)hex-2-en-4-yne affords not only the regiospecific addition of the nucleophile at C(5) but also effects concomitant vinylic and allylic displacements at C(1) and (2). ... Additions to conjugated enynes have ...
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Alkynes, when carrying an α-sulfonyl group, are shown to be stereoselectively reduced to z-alkene... more Alkynes, when carrying an α-sulfonyl group, are shown to be stereoselectively reduced to z-alkenes using sodium borohydride under mildly basic conditions.
Phosphorus Sulfur and Silicon and The Related Elements, 1991
Phosphorus, Sulfur, and Silicon, 1991, Vol. 57. pp. 17-23 Reprints available directly from the pu... more Phosphorus, Sulfur, and Silicon, 1991, Vol. 57. pp. 17-23 Reprints available directly from the publisher Photocopying permitted by license only 0 1991 Gordon and Breach Science Publishen SA Printed in the United Kingdom ... ANIONIC ADDITIONS TO CONJUGATED ENYNES- ...
Journal of The Chemical Society, Chemical Communications, 1990
Reaction of sodium benzenesulphinate with I ,2-di(4-chlorobenzenesulphonyl)hex-2-en-4-yne affords... more Reaction of sodium benzenesulphinate with I ,2-di(4-chlorobenzenesulphonyl)hex-2-en-4-yne affords not only the regiospecific addition of the nucleophile at C(5) but also effects concomitant vinylic and allylic displacements at C(1) and (2). ... Additions to conjugated enynes have ...
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Iatrogenic lumbar artery pseudoaneurysm is a very rare complication of spinal surgery. To the bes... more Iatrogenic lumbar artery pseudoaneurysm is a very rare complication of spinal surgery. To the best of our knowledge, this is the first report of a lumbar artery pseudoaneurysm after extreme lateral interbody fusion (XLIF). The lesion was diagnosed by catheter spinal angiography and was effectively treated with embolization.
Cervical hemangiopericytoma (HPC) is a rare tumor involving dura and bone. Because HPC shares som... more Cervical hemangiopericytoma (HPC) is a rare tumor involving dura and bone. Because HPC shares some imaging features with meningioma, hemangioblastoma, schwannoma and solitary fibrous tumors; histology with appropriate immunohistochemistry is essential for its diagnosis and treatment. HPC is highly vascular and has a high rate of local recurrence following resection. Thus it can pose significant therapeutic challenges. To the best of our knowledge this is the 13th reported case of HPC of the cervical spine and the first case of cervical HPC treated using embolization with Onyx-18. In addition, a systematic review of the literature is presented describing previous experience with HPC of the cervical region. The case of a 61-year-old woman is reported who presented with a 7 month history of dizziness, mild ataxia and left-sided tinnitus when supine. MRI of the cervical spine demonstrated a gadolinium enhancing mass arising from the dorsal cervical dura, extending from the occiput to C2, with internal flow voids and extension into the C2 lamina and spinous process. Digital subtraction angiography demonstrated multiple corkscrew-shaped supplying vessels, marked hypervascularity, rapid arteriovenous shunting and delayed contrast washout. Super selective injection of Onyx-18 yielded approximately 90% embolization of the lesion, followed by subtotal resection and radiotherapy. Histology confirmed the presumptive diagnosis of HPC. Preoperative embolization with Onyx-18 should be considered for large HPC as it may decrease the risk of intraoperative hemorrhage. In this case, embolization with Onyx-18 did not preclude histopathologic diagnosis of HPC.
PurposeIntracranial atherosclerotic disease (ICAD) is one of the leading causes of ischemic strok... more PurposeIntracranial atherosclerotic disease (ICAD) is one of the leading causes of ischemic stroke worldwide. Percutaneous transluminal angioplasty (PTA) and stenting has emerged as a treatment for ICAD since there is a significant risk of recurrent ischemic stroke with medical management. We present data of our experience with PTA and stenting for ICAD and demonstrate an association between past or current smoking and risk of recurrent stroke or transient ischemic attack in the treated vessel territory.Materials and MethodsA retrospective review was conducted of 29 patients with symptomatic ICAD >70% who failed medical management and underwent angioplasty and stenting between July 2005 and August 2010. Patients were classified as symptomatic or asymptomatic. Symptomatic patients were defined as having a recurrent ischemic stroke or transient ischemic attack in the vascular territory of the treated vessel. Rates of in-stent restenosis, hypertension, history of smoking or current smoking, diabetes, hyperlipidemia and location of stenosis were compared in symptomatic vs asymptomatic patients. The effects of past or current smoking, hypertension, diabetes and hyperlipidemia on rates of in-stent restenosis were also compared.Results29 patients with symptomatic intracranial stenosis >70% underwent angioplasty and stenting of intracranial lesions; 26 returned for clinical follow-up. The procedural success rate, defined as more than 50% endoluminal revascularization of the stenotic lesion after stent deployment was 97%. There were no procedural complications. The average period of clinical and radiographic follow-up was 1.8 years. Three patients had strokes (11.5%) and two patients had a transient ischemic attack (7.7%) in the territory of the affected vessel over the follow-up period. The risk of ischemic stroke, transient ischemic attack, intracerebral hemorrhage or death at 30 days was zero. The incidence of ischemic stroke in the treated vessel territory was 7.7% at 6 months and 11.5% at 1 year. The incidence of ischemic stroke or TIA in the affected vessel at 1 year was 15.4%. From 1 year after the procedure to the end of the follow-up period there were no further strokes and only one TIA in the affected vessel territory. Of the modifiable risk factors, only past or current smoking had a statistically significant association with the symptomatic group (p=0.020). Diabetes, hypertension and hyperlipidemia were not associated with symptomatic patients. In-stent restenosis was also associated with the symptomatic group (p=0.028). There was no association of past or current smoking, hypertension, diabetes or hyperlipidemia with in-stent restenosis.ConclusionsOf the vascular risk factors studied, past or current history of smoking was associated with recurrent ischemic stroke or transient ischemic attack in a treated vessel territory following successful PTA and stenting in ICAD. There was no association of smoking, hypertension, diabetes or hyperlipidemia with in-stent restenosis. Despite the relatively small number of patients, this study emphasizes the importance of smoking cessation in patients with ICAD undergoing angioplasty and stenting and also demonstrates that former smokers have higher risk of recurrent ischemia and should be risk-stratified accordingly.
PurposeThe safety of the balloon remodeling technique remains a matter of debate. In this report ... more PurposeThe safety of the balloon remodeling technique remains a matter of debate. In this report we analyze the safety of the balloon remodeling technique compared with coil embolization alone for the treatment of ruptured and unruptured intracranial aneurysms.Material and MethodsWe retrospectively reviewed the medical records, procedures notes, and angiograms of 491 patients treated with coil embolization alone and the balloon
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Alkynes, when carrying an α-sulfonyl group, are shown to be stereoselectively reduced to z-alkene... more Alkynes, when carrying an α-sulfonyl group, are shown to be stereoselectively reduced to z-alkenes using sodium borohydride under mildly basic conditions.
Phosphorus Sulfur and Silicon and The Related Elements, 1991
Phosphorus, Sulfur, and Silicon, 1991, Vol. 57. pp. 17-23 Reprints available directly from the pu... more Phosphorus, Sulfur, and Silicon, 1991, Vol. 57. pp. 17-23 Reprints available directly from the publisher Photocopying permitted by license only 0 1991 Gordon and Breach Science Publishen SA Printed in the United Kingdom ... ANIONIC ADDITIONS TO CONJUGATED ENYNES- ...
Journal of The Chemical Society, Chemical Communications, 1990
Reaction of sodium benzenesulphinate with I ,2-di(4-chlorobenzenesulphonyl)hex-2-en-4-yne affords... more Reaction of sodium benzenesulphinate with I ,2-di(4-chlorobenzenesulphonyl)hex-2-en-4-yne affords not only the regiospecific addition of the nucleophile at C(5) but also effects concomitant vinylic and allylic displacements at C(1) and (2). ... Additions to conjugated enynes have ...
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Alkynes, when carrying an α-sulfonyl group, are shown to be stereoselectively reduced to z-alkene... more Alkynes, when carrying an α-sulfonyl group, are shown to be stereoselectively reduced to z-alkenes using sodium borohydride under mildly basic conditions.
Phosphorus Sulfur and Silicon and The Related Elements, 1991
Phosphorus, Sulfur, and Silicon, 1991, Vol. 57. pp. 17-23 Reprints available directly from the pu... more Phosphorus, Sulfur, and Silicon, 1991, Vol. 57. pp. 17-23 Reprints available directly from the publisher Photocopying permitted by license only 0 1991 Gordon and Breach Science Publishen SA Printed in the United Kingdom ... ANIONIC ADDITIONS TO CONJUGATED ENYNES- ...
Journal of The Chemical Society, Chemical Communications, 1990
Reaction of sodium benzenesulphinate with I ,2-di(4-chlorobenzenesulphonyl)hex-2-en-4-yne affords... more Reaction of sodium benzenesulphinate with I ,2-di(4-chlorobenzenesulphonyl)hex-2-en-4-yne affords not only the regiospecific addition of the nucleophile at C(5) but also effects concomitant vinylic and allylic displacements at C(1) and (2). ... Additions to conjugated enynes have ...
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Iatrogenic lumbar artery pseudoaneurysm is a very rare complication of spinal surgery. To the bes... more Iatrogenic lumbar artery pseudoaneurysm is a very rare complication of spinal surgery. To the best of our knowledge, this is the first report of a lumbar artery pseudoaneurysm after extreme lateral interbody fusion (XLIF). The lesion was diagnosed by catheter spinal angiography and was effectively treated with embolization.
Cervical hemangiopericytoma (HPC) is a rare tumor involving dura and bone. Because HPC shares som... more Cervical hemangiopericytoma (HPC) is a rare tumor involving dura and bone. Because HPC shares some imaging features with meningioma, hemangioblastoma, schwannoma and solitary fibrous tumors; histology with appropriate immunohistochemistry is essential for its diagnosis and treatment. HPC is highly vascular and has a high rate of local recurrence following resection. Thus it can pose significant therapeutic challenges. To the best of our knowledge this is the 13th reported case of HPC of the cervical spine and the first case of cervical HPC treated using embolization with Onyx-18. In addition, a systematic review of the literature is presented describing previous experience with HPC of the cervical region. The case of a 61-year-old woman is reported who presented with a 7 month history of dizziness, mild ataxia and left-sided tinnitus when supine. MRI of the cervical spine demonstrated a gadolinium enhancing mass arising from the dorsal cervical dura, extending from the occiput to C2, with internal flow voids and extension into the C2 lamina and spinous process. Digital subtraction angiography demonstrated multiple corkscrew-shaped supplying vessels, marked hypervascularity, rapid arteriovenous shunting and delayed contrast washout. Super selective injection of Onyx-18 yielded approximately 90% embolization of the lesion, followed by subtotal resection and radiotherapy. Histology confirmed the presumptive diagnosis of HPC. Preoperative embolization with Onyx-18 should be considered for large HPC as it may decrease the risk of intraoperative hemorrhage. In this case, embolization with Onyx-18 did not preclude histopathologic diagnosis of HPC.
PurposeIntracranial atherosclerotic disease (ICAD) is one of the leading causes of ischemic strok... more PurposeIntracranial atherosclerotic disease (ICAD) is one of the leading causes of ischemic stroke worldwide. Percutaneous transluminal angioplasty (PTA) and stenting has emerged as a treatment for ICAD since there is a significant risk of recurrent ischemic stroke with medical management. We present data of our experience with PTA and stenting for ICAD and demonstrate an association between past or current smoking and risk of recurrent stroke or transient ischemic attack in the treated vessel territory.Materials and MethodsA retrospective review was conducted of 29 patients with symptomatic ICAD >70% who failed medical management and underwent angioplasty and stenting between July 2005 and August 2010. Patients were classified as symptomatic or asymptomatic. Symptomatic patients were defined as having a recurrent ischemic stroke or transient ischemic attack in the vascular territory of the treated vessel. Rates of in-stent restenosis, hypertension, history of smoking or current smoking, diabetes, hyperlipidemia and location of stenosis were compared in symptomatic vs asymptomatic patients. The effects of past or current smoking, hypertension, diabetes and hyperlipidemia on rates of in-stent restenosis were also compared.Results29 patients with symptomatic intracranial stenosis >70% underwent angioplasty and stenting of intracranial lesions; 26 returned for clinical follow-up. The procedural success rate, defined as more than 50% endoluminal revascularization of the stenotic lesion after stent deployment was 97%. There were no procedural complications. The average period of clinical and radiographic follow-up was 1.8 years. Three patients had strokes (11.5%) and two patients had a transient ischemic attack (7.7%) in the territory of the affected vessel over the follow-up period. The risk of ischemic stroke, transient ischemic attack, intracerebral hemorrhage or death at 30 days was zero. The incidence of ischemic stroke in the treated vessel territory was 7.7% at 6 months and 11.5% at 1 year. The incidence of ischemic stroke or TIA in the affected vessel at 1 year was 15.4%. From 1 year after the procedure to the end of the follow-up period there were no further strokes and only one TIA in the affected vessel territory. Of the modifiable risk factors, only past or current smoking had a statistically significant association with the symptomatic group (p=0.020). Diabetes, hypertension and hyperlipidemia were not associated with symptomatic patients. In-stent restenosis was also associated with the symptomatic group (p=0.028). There was no association of past or current smoking, hypertension, diabetes or hyperlipidemia with in-stent restenosis.ConclusionsOf the vascular risk factors studied, past or current history of smoking was associated with recurrent ischemic stroke or transient ischemic attack in a treated vessel territory following successful PTA and stenting in ICAD. There was no association of smoking, hypertension, diabetes or hyperlipidemia with in-stent restenosis. Despite the relatively small number of patients, this study emphasizes the importance of smoking cessation in patients with ICAD undergoing angioplasty and stenting and also demonstrates that former smokers have higher risk of recurrent ischemia and should be risk-stratified accordingly.
PurposeThe safety of the balloon remodeling technique remains a matter of debate. In this report ... more PurposeThe safety of the balloon remodeling technique remains a matter of debate. In this report we analyze the safety of the balloon remodeling technique compared with coil embolization alone for the treatment of ruptured and unruptured intracranial aneurysms.Material and MethodsWe retrospectively reviewed the medical records, procedures notes, and angiograms of 491 patients treated with coil embolization alone and the balloon
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