A magnesium alloy AZ31 was processed by high-pressure torsion (HPT) at room temperature. Microstr... more A magnesium alloy AZ31 was processed by high-pressure torsion (HPT) at room temperature. Microstructure investigations show the material has a grain size as fine as ~450 nm after 5 turns of HPT processing. X-ray texture measurements show most grains have the {0001} fibre, with their c-axis parallel to the HPT torsion axis. Tensile specimens were cut from HPT disc and pulled to failure over a range of strain rates (4.) at temperatures of 623 and 673 K. The tensile elongations from HPT specimens are lower than for published results using equal-channel angular processing (ECAP) specimens although AZ31 has a finer grain size after HPT than after ECAP. The reasons for the lower elongations in HPT specimens are related to the thermal stability of the processed microstructure, the texture components and the tensile specimen size. Earlier investigations confirmed there was significant grain growth at 623 and 673 K in HPT samples, which would contribute to the low ductility of AZ31 in tensil...
By Fernando de Holanda Barbosa and Pedro L. Valls Pereira; Insucesso do Plano Cruzado: A Evidênci... more By Fernando de Holanda Barbosa and Pedro L. Valls Pereira; Insucesso do Plano Cruzado: A Evidência Empírica da Inflação 100% Inércia Para o Brasil.
ABSTRACT Context. To assess the real impact of human-made structures on bird and bat communities,... more ABSTRACT Context. To assess the real impact of human-made structures on bird and bat communities, a significant number of carcass-removal trials has been performed worldwide in recent decades. Recently, researchers have started to use camera traps to record carcasses exact removal time and better understand the factors that influence this event. Aims. In our study, we endeavoured to identify the factors that significantly affect carcass-persistence time, such as (1) season, (2) scavenger guild, (3) type of carcass, (4) habitat and (5) weather conditions. Additionally, we aimed to assess the performance of camera-trapping technology in comparison to the conventional method typically used in carcassremoval trials. Methods. We conducted two trials in two wind farms during early spring and during summer season. In each trial, we used 30 bird carcasses and 30 mice carcasses as surrogates for bats. Digital infrared camera traps were used to monitor each carcass. Chi-squared test was used to investigate differences between wind farms regarding the scavenger guild.A logrank test was used to compare carcass-persistence times for both wind farms. Carcass-persistence times were analysed using both non-parametric and parametric survival models. Finally, we evaluated the percentage of carcasses removed during the day time and night time. Key results. In our study area, carcass-persistence times were influenced by the scavenger guild present and by the exposure to rain. Camera traps allowed to record the exact removal time for the majority of the carcasses, reducing the number of visits to the study site about five times. However, there were also cases wherein loss of data occurred as a result of equipment flaws or camera theft. Conclusions. Results demonstrated the importance of undertaking site-specific carcass-removal trials. Use of cameratrap methodology is a valid option, reducing displacement costs. Costs related to equipment purchase and the risk of camera theft should be taken into consideration. Implications. When choosing camera-trapping, the main aspect to evaluate is the balance between the investment in equipment purchase and the cost savings through reduced displacement costs. Further studies are required concerning the real effects of the data collected on the accuracy of carcass-removal correction factor obtained.
Revista Brasileira de Ginecologia e Obstetrícia, 2002
Objetivos: comparar resultados entre gestações com e sem ameaça de abortamento que apresentaram e... more Objetivos: comparar resultados entre gestações com e sem ameaça de abortamento que apresentaram embrião/feto vivo ao exame ultra-sonográfico em idade gestacional entre 6 e 13 semanas. Métodos: trata-se de estudo retrospectivo, caso-controle, realizado no período de ...
Sandra Macedo-Ribeiro majored in Biochemistry and graduated from the University of Porto (Portuga... more Sandra Macedo-Ribeiro majored in Biochemistry and graduated from the University of Porto (Portugal) (1992). After completing a Ph.D. in Protein Crystallography with Prof. Robert Huber at the Technical University of Munich, Germany (1999), she joined the group of Dr. Miquel ...
Nature is the international weekly journal of science: a magazine style journal that publishes fu... more Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and ...
We analyze the product differentiation decision of a downstream entrant that purchases access to ... more We analyze the product differentiation decision of a downstream entrant that purchases access to a bottleneck input from one of two vertically integrated incumbents, who will compete with him in the downstream market. First, an entrant chooses his product, then the entrant ...
Candida albicans is a polymorphic opportunistic fungal pathogen normally residing as commensal on... more Candida albicans is a polymorphic opportunistic fungal pathogen normally residing as commensal on mucosal surfaces, skin and gastrointestinal and genitourinary tracts. However, in immunocompromised patients C. albicans can cause superficial mucosal infections or life-threatening disseminated candidemia. A change in physiological conditions triggers a cascade of molecular events leading to morphogenetic alterations and increased resistance to damage induced by host defenses. The complex biology of this human pathogen is reflected in its morphological plasticity and reinforced by the ability to ambiguously translate the universal leucine CUG codon predominantly as serine, but also as leucine. Mistranslation affects more than half of C. albicans proteome and it is widespread across many biological processes. A previous analysis of CTG-codon containing gene products in C. albicans suggested that codon ambiguity subtly shapes protein function and might have a pivotal role in signaling cascades associated with morphological changes and pathogenesis. In this review we further explore this hypothesis by highlighting the role of ambiguous decoding in macromolecular recognition of key effector proteins associated with the regulation of signal transduction cascades and the cell cycle, which are critical processes for C. albicans morphogenic plasticity under a variety of environmental conditions.
A magnesium alloy AZ31 was processed by high-pressure torsion (HPT) at room temperature. Microstr... more A magnesium alloy AZ31 was processed by high-pressure torsion (HPT) at room temperature. Microstructure investigations show the material has a grain size as fine as ~450 nm after 5 turns of HPT processing. X-ray texture measurements show most grains have the {0001} fibre, with their c-axis parallel to the HPT torsion axis. Tensile specimens were cut from HPT disc and pulled to failure over a range of strain rates (4.) at temperatures of 623 and 673 K. The tensile elongations from HPT specimens are lower than for published results using equal-channel angular processing (ECAP) specimens although AZ31 has a finer grain size after HPT than after ECAP. The reasons for the lower elongations in HPT specimens are related to the thermal stability of the processed microstructure, the texture components and the tensile specimen size. Earlier investigations confirmed there was significant grain growth at 623 and 673 K in HPT samples, which would contribute to the low ductility of AZ31 in tensil...
By Fernando de Holanda Barbosa and Pedro L. Valls Pereira; Insucesso do Plano Cruzado: A Evidênci... more By Fernando de Holanda Barbosa and Pedro L. Valls Pereira; Insucesso do Plano Cruzado: A Evidência Empírica da Inflação 100% Inércia Para o Brasil.
ABSTRACT Context. To assess the real impact of human-made structures on bird and bat communities,... more ABSTRACT Context. To assess the real impact of human-made structures on bird and bat communities, a significant number of carcass-removal trials has been performed worldwide in recent decades. Recently, researchers have started to use camera traps to record carcasses exact removal time and better understand the factors that influence this event. Aims. In our study, we endeavoured to identify the factors that significantly affect carcass-persistence time, such as (1) season, (2) scavenger guild, (3) type of carcass, (4) habitat and (5) weather conditions. Additionally, we aimed to assess the performance of camera-trapping technology in comparison to the conventional method typically used in carcassremoval trials. Methods. We conducted two trials in two wind farms during early spring and during summer season. In each trial, we used 30 bird carcasses and 30 mice carcasses as surrogates for bats. Digital infrared camera traps were used to monitor each carcass. Chi-squared test was used to investigate differences between wind farms regarding the scavenger guild.A logrank test was used to compare carcass-persistence times for both wind farms. Carcass-persistence times were analysed using both non-parametric and parametric survival models. Finally, we evaluated the percentage of carcasses removed during the day time and night time. Key results. In our study area, carcass-persistence times were influenced by the scavenger guild present and by the exposure to rain. Camera traps allowed to record the exact removal time for the majority of the carcasses, reducing the number of visits to the study site about five times. However, there were also cases wherein loss of data occurred as a result of equipment flaws or camera theft. Conclusions. Results demonstrated the importance of undertaking site-specific carcass-removal trials. Use of cameratrap methodology is a valid option, reducing displacement costs. Costs related to equipment purchase and the risk of camera theft should be taken into consideration. Implications. When choosing camera-trapping, the main aspect to evaluate is the balance between the investment in equipment purchase and the cost savings through reduced displacement costs. Further studies are required concerning the real effects of the data collected on the accuracy of carcass-removal correction factor obtained.
Revista Brasileira de Ginecologia e Obstetrícia, 2002
Objetivos: comparar resultados entre gestações com e sem ameaça de abortamento que apresentaram e... more Objetivos: comparar resultados entre gestações com e sem ameaça de abortamento que apresentaram embrião/feto vivo ao exame ultra-sonográfico em idade gestacional entre 6 e 13 semanas. Métodos: trata-se de estudo retrospectivo, caso-controle, realizado no período de ...
Sandra Macedo-Ribeiro majored in Biochemistry and graduated from the University of Porto (Portuga... more Sandra Macedo-Ribeiro majored in Biochemistry and graduated from the University of Porto (Portugal) (1992). After completing a Ph.D. in Protein Crystallography with Prof. Robert Huber at the Technical University of Munich, Germany (1999), she joined the group of Dr. Miquel ...
Nature is the international weekly journal of science: a magazine style journal that publishes fu... more Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and ...
We analyze the product differentiation decision of a downstream entrant that purchases access to ... more We analyze the product differentiation decision of a downstream entrant that purchases access to a bottleneck input from one of two vertically integrated incumbents, who will compete with him in the downstream market. First, an entrant chooses his product, then the entrant ...
Candida albicans is a polymorphic opportunistic fungal pathogen normally residing as commensal on... more Candida albicans is a polymorphic opportunistic fungal pathogen normally residing as commensal on mucosal surfaces, skin and gastrointestinal and genitourinary tracts. However, in immunocompromised patients C. albicans can cause superficial mucosal infections or life-threatening disseminated candidemia. A change in physiological conditions triggers a cascade of molecular events leading to morphogenetic alterations and increased resistance to damage induced by host defenses. The complex biology of this human pathogen is reflected in its morphological plasticity and reinforced by the ability to ambiguously translate the universal leucine CUG codon predominantly as serine, but also as leucine. Mistranslation affects more than half of C. albicans proteome and it is widespread across many biological processes. A previous analysis of CTG-codon containing gene products in C. albicans suggested that codon ambiguity subtly shapes protein function and might have a pivotal role in signaling cascades associated with morphological changes and pathogenesis. In this review we further explore this hypothesis by highlighting the role of ambiguous decoding in macromolecular recognition of key effector proteins associated with the regulation of signal transduction cascades and the cell cycle, which are critical processes for C. albicans morphogenic plasticity under a variety of environmental conditions.
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