Laboratory services have been described as the major processes contributing to safe patient care ... more Laboratory services have been described as the major processes contributing to safe patient care in the modern healthcare sector. However, occurrences of errors in the overall testing processes impair the clinical decision-making process. Such errors are supposed to be high in resourcepoor countries, like Ethiopia. Therefore, this study was aimed to assess errors in the total testing process in the Clinical Chemistry Laboratory of University of Gondar Hospital. For this purpose, a cross-sectional study was conducted at the University of Gondar Hospital from February to March 2016. All the required data were collected using established quality indicators. Data were analyzed using SPSS version 20. Frequencies and cross tabulations were used to summarize descriptive statistics. A total of 3259 samples and corresponding laboratory request forms were received for analysis. Analysis of the overall distribution of errors reveals that 89.6% were pre-analytical errors, 2.6% were analytical, ...
Background: Hyperuricemia is associated with cardiovascular disease (CVD) that presents in diabet... more Background: Hyperuricemia is associated with cardiovascular disease (CVD) that presents in diabetes mellitus patients. Therefore, the aim of this study was to appraise the serum uric acid and its association with CVD risk factors among diabetes mellitus patients. Methods: A cross-sectional study was carried out at the University of Gondar hospital from February to March, 2018. A total of 384 study participants were selected by systematic random sampling technique. Five milliliter blood sample was collected and analyzed using Mindray BS-200E machine. The data was analysed into SPSS version 20. Logistic regression model was used to investigate associated factors. A p-value <0.05 was considered statistically significant. Results: The prevalence of hyperuricemia among type 2 diabetic patients was 31.5%. The serum uric acid concentration was higher among male (33.1%) compared to female (28.9%). Elevated systolic blood pressure (AOR: 4.4, 95%CI: 2.1-9.3), family history of DM (AOR: 1.5, 95%CI: 1.2-2.5) and BMI ≥ 25 Kg/m2 (AOR: 1.4, 95%CI: 1.1-3.7) were significantly associated with hyperuricemia. Increased BMI (52.4%), high waist circumference (63.0%) and elevated systolic blood pressure (58.2%) were the major CVD risk factors. Conclusion: The prevalence of hyperuricemia was high in type 2 diabetes patients. The major predictors of CVD risk factors were elevated systolic blood pressure, family history of DM and BMI ≥ 25 Kg/m2 which lead to early diagnosis and treatment for hyperuricemia. Lastly, CVD risk factors are essential to reduce the disease among type 2 diabetic patients.
Background: Pregnancy is a natural physiological variation as a result of hormonic and metabolic ... more Background: Pregnancy is a natural physiological variation as a result of hormonic and metabolic changes, which helps the growth and survival of the fetus. Worldwide more than 500,000 women are expected to have died each year as a result of pregnancy complication related to hematological profile alterations. Therefore the aim of the study was to assess hematological profiles of pregnant women attending at University of Gondar Hospital, Northwest Ethiopia. Methods: A comparative cross sectional study was conducted among pregnant and non-pregnant women at University of Gondar Hospital, Antenatal care clinic from February to April, 2015. Blood sample was collected from 139 pregnant and 139 age matched non-pregnant women using systematic random sampling technique. Data analysis was made using SPSS version 20. Level of significance between groups was analyzed using independent t test and Mann-Whitney test. P-value <0.05 was considered statistically significant. Result: Overall, the va...
Comparable data on the global and country-specific burden of neurological disorders and their tre... more Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this systematic analysis, we quantified the global disease burden due to neurological disorders in 2015 and its relationship with country development level. We estimated global and country-specific prevalence, mortality, disability-adjusted life-years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) for various neurological disorders that in the GBD classification have been previously spread across multiple disease groupings. The more inclusive grouping of neurological disorders included stroke, meningitis, encephalitis, tetanus, Alzheimer's disease and other dementias, Parkinson&#...
Cancer is the second leading cause of death worldwide. Current estimates on the burden of cancer ... more Cancer is the second leading cause of death worldwide. Current estimates on the burden of cancer are needed for cancer control planning. To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 32 cancers in 195 countries and territories from 1990 to 2015. Cancer mortality was estimated using vital registration system data, cancer registry incidence data (transformed to mortality estimates using separately estimated mortality to incidence [MI] ratios), and verbal autopsy data. Cancer incidence was calculated by dividing mortality estimates through the modeled MI ratios. To calculate cancer prevalence, MI ratios were used to model survival. To calculate YLDs, prevalence estimates were multiplied by disability weights. The YLLs were estimated by multiplying age-specific cancer deaths by the reference life expectancy. DALYs were estimated as the sum of YLDs and YLLs. A sociodemographic index (SDI) wa...
Laboratory services have been described as the major processes contributing to safe patient care ... more Laboratory services have been described as the major processes contributing to safe patient care in the modern healthcare sector. However, occurrences of errors in the overall testing processes impair the clinical decision-making process. Such errors are supposed to be high in resourcepoor countries, like Ethiopia. Therefore, this study was aimed to assess errors in the total testing process in the Clinical Chemistry Laboratory of University of Gondar Hospital. For this purpose, a cross-sectional study was conducted at the University of Gondar Hospital from February to March 2016. All the required data were collected using established quality indicators. Data were analyzed using SPSS version 20. Frequencies and cross tabulations were used to summarize descriptive statistics. A total of 3259 samples and corresponding laboratory request forms were received for analysis. Analysis of the overall distribution of errors reveals that 89.6% were pre-analytical errors, 2.6% were analytical, ...
Background: Hyperuricemia is associated with cardiovascular disease (CVD) that presents in diabet... more Background: Hyperuricemia is associated with cardiovascular disease (CVD) that presents in diabetes mellitus patients. Therefore, the aim of this study was to appraise the serum uric acid and its association with CVD risk factors among diabetes mellitus patients. Methods: A cross-sectional study was carried out at the University of Gondar hospital from February to March, 2018. A total of 384 study participants were selected by systematic random sampling technique. Five milliliter blood sample was collected and analyzed using Mindray BS-200E machine. The data was analysed into SPSS version 20. Logistic regression model was used to investigate associated factors. A p-value <0.05 was considered statistically significant. Results: The prevalence of hyperuricemia among type 2 diabetic patients was 31.5%. The serum uric acid concentration was higher among male (33.1%) compared to female (28.9%). Elevated systolic blood pressure (AOR: 4.4, 95%CI: 2.1-9.3), family history of DM (AOR: 1.5, 95%CI: 1.2-2.5) and BMI ≥ 25 Kg/m2 (AOR: 1.4, 95%CI: 1.1-3.7) were significantly associated with hyperuricemia. Increased BMI (52.4%), high waist circumference (63.0%) and elevated systolic blood pressure (58.2%) were the major CVD risk factors. Conclusion: The prevalence of hyperuricemia was high in type 2 diabetes patients. The major predictors of CVD risk factors were elevated systolic blood pressure, family history of DM and BMI ≥ 25 Kg/m2 which lead to early diagnosis and treatment for hyperuricemia. Lastly, CVD risk factors are essential to reduce the disease among type 2 diabetic patients.
Background: Pregnancy is a natural physiological variation as a result of hormonic and metabolic ... more Background: Pregnancy is a natural physiological variation as a result of hormonic and metabolic changes, which helps the growth and survival of the fetus. Worldwide more than 500,000 women are expected to have died each year as a result of pregnancy complication related to hematological profile alterations. Therefore the aim of the study was to assess hematological profiles of pregnant women attending at University of Gondar Hospital, Northwest Ethiopia. Methods: A comparative cross sectional study was conducted among pregnant and non-pregnant women at University of Gondar Hospital, Antenatal care clinic from February to April, 2015. Blood sample was collected from 139 pregnant and 139 age matched non-pregnant women using systematic random sampling technique. Data analysis was made using SPSS version 20. Level of significance between groups was analyzed using independent t test and Mann-Whitney test. P-value <0.05 was considered statistically significant. Result: Overall, the va...
Comparable data on the global and country-specific burden of neurological disorders and their tre... more Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this systematic analysis, we quantified the global disease burden due to neurological disorders in 2015 and its relationship with country development level. We estimated global and country-specific prevalence, mortality, disability-adjusted life-years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) for various neurological disorders that in the GBD classification have been previously spread across multiple disease groupings. The more inclusive grouping of neurological disorders included stroke, meningitis, encephalitis, tetanus, Alzheimer's disease and other dementias, Parkinson&#...
Cancer is the second leading cause of death worldwide. Current estimates on the burden of cancer ... more Cancer is the second leading cause of death worldwide. Current estimates on the burden of cancer are needed for cancer control planning. To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 32 cancers in 195 countries and territories from 1990 to 2015. Cancer mortality was estimated using vital registration system data, cancer registry incidence data (transformed to mortality estimates using separately estimated mortality to incidence [MI] ratios), and verbal autopsy data. Cancer incidence was calculated by dividing mortality estimates through the modeled MI ratios. To calculate cancer prevalence, MI ratios were used to model survival. To calculate YLDs, prevalence estimates were multiplied by disability weights. The YLLs were estimated by multiplying age-specific cancer deaths by the reference life expectancy. DALYs were estimated as the sum of YLDs and YLLs. A sociodemographic index (SDI) wa...
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