2021 marks the 50th anniversary of the death of Jakub Rothfeld-Rostowski, an eminent neurologist,... more 2021 marks the 50th anniversary of the death of Jakub Rothfeld-Rostowski, an eminent neurologist, academic teacher, military doctor and amateur sculptor (Fig. 1) [1, 2]. His experimental studies and clinical observations, made before World War II, contributed to the development of knowledge and differential diagnosis of extrapyramidal syndromes, “gelolepsy” and “orgasmolepsy” [1, 3, 4]. He related the flexion reflex (Balduzzi-Rothfeld sign), described in 1926 by the Italian psychiatrist Ottorino Balduzzi (1897–1964), with the diagnosis of the location of brain tumors [5, 6]. Jakub Rothfeld-Rostowski was born into a Jewish family on February 4, 1884 in Bukachivtsy which belonged to Austro-Hungarian Empire (eastern Poland between the world wars, western Ukraine today). He was the son of Mojżesz Rotfeld and Lea nee Broder. After graduating from gymnasium in Lviv, he studied medicine at the Faculty of Medicine at the University of Lviv [2]. He obtained his doctor’s degree in medicine on March 31, 1909. In 1910, he became an assistant in the neurological outpatient clinic headed by Henryk Blumenstok-Halban (1870–1933). Before the outbreak of World War I, he worked in neurological clinics in Vienna and Hamburg. Rothfeld took an active part in neurological conferences–he gave lectures at the Congress of Neurologists in Crakow in 1912, and the following year in Wroclaw and Ghent. After the outbreak of World War I in 1914, he was called up to the Austrian Army and worked as a neurologist in military hospitals. After the end of hostilities, he returned to clinical and scientific work at the Institute of Physiology at the University of Lviv. He obtained his habilitation in 1919 on the basis of the dissertation “On the influence of the frontal lobe on motor reactions from the vestibular ear organ” [2]. After the restoration of Polish statehood, he joined the Polish Army, where he was promoted to the rank of major in the corps of medical sanitary officers. In 1920, he took part, as a doctor, in the Polish-Soviet War. He went to the army reserve in 1921. From that time, Rothfeld worked in the Department of Neurology of the University of Lviv, established by Blumenstok-Halban as a professor assistant. He became a titular professor of the Faculty of Medicine at the Jan Kazimierz University in Lviv in 1928. From 1933 to 1936, he headed the Clinic of Neurology [1, 2]. Shortly, before the outbreak of World War II, he finished writing a neurology textbook, publication of which was thwarted by the war. In 1939, as a military doctor, he took part in the first stage of World War II. After the defeat of the Polish army in the fight against the Nazi invaders, he managed to flee via Hungary to France, where he worked as a neurologist in a military hospital. In June 1940, after the Third Reich’s aggression against France, Rothfeld evacuated to Great Britain. From 1941, he headed the department of neurology in a military hospital in Scotland. Then, he changed his name to Rostowski [2]. He was a member of the Health Committee at the Ministry of Labor and Social Welfare of the Polish Government in London. He was a professor of neurology (from March 1941) and the Dean (1946–1949) of the Polish School of Medicine at the University of Edinburgh. Rothfeld-Rostowski did not return to Poland after World War II. In 1949–54, he worked as a consultant in the Department of Psychiatry of the Royal Edinburgh Hospital [1, 2]. In 1966, Rothfeld-Rostowski received an honorary degree of Doctor of Laws (LL.D.) of Alma Mater Edinburgensis. In the post-war period, he started carving. His works have been exhibited in Edinburgh and London. His sculpture "Their last Prayer at Belsen Camp" referring to the suffering of prisoners of the German Nazi concentration camps, was exhibited at the Royal Scottich Academy [1]. His wife * Jarosław Sak jareksak@tlen.pl
Artificial intelligence (AI) as a branch of computer science, the purpose of which is to imitate ... more Artificial intelligence (AI) as a branch of computer science, the purpose of which is to imitate thought processes, learning abilities and knowledge management, finds more and more applications in experimental and clinical medicine. In recent decades, there has been an expansion of AI applications in biomedical sciences. The possibilities of artificial intelligence in the field of medical diagnostics, risk prediction and support of therapeutic techniques are growing rapidly. The aim of the article is to analyze the current use of AI in nutrients science research. The literature review was conducted in PubMed. A total of 399 records published between 1987 and 2020 were obtained, of which, after analyzing the titles and abstracts, 261 were rejected. In the next stages, the remaining records were analyzed using the full-text versions and, finally, 55 papers were selected. These papers were divided into three areas: AI in biomedical nutrients research (20 studies), AI in clinical nutrie...
International Journal of Environmental Research and Public Health
In view of previous reports, it is important to determine the relationship between liver function... more In view of previous reports, it is important to determine the relationship between liver function and the level of fluoride in the serum. The aim of this study was to investigate serum concentrations of fluoride in 72 patients with alcoholic liver cirrhosis, living in the region of Lublin (Eastern Poland) divided based on the severity of disease according to the Child-Turcotte-Pugh criteria. Higher plasma fluoride concentrations were associated with changes in liver related parameters. In all groups of analyzed patients with different stages of alcoholic liver cirrhosis, elevated levels of plasma fluoride and increased activities of both alanine aminotransferase (ALT) and total bilirubin concentration were shown.
Introduction: Liver cirrhosis develops in about 10% of alcohol abusers. To date, a number of cell... more Introduction: Liver cirrhosis develops in about 10% of alcohol abusers. To date, a number of cells and cytokines have been identified, which are involved in induction of liver fibrotic processes. Nevertheless, the pathogenesis of liver cirrhosis has not been fully elucidated. The aim of the present study was to determine serum concentrations of afamin and adropin in patients with alcoholic liver cirrhosis and to define their correlation with the stage of disease. Materials and methods: The study included 99 patients with alcoholic cirrhosis from the region of Lublin, (Eastern Poland). Liver cirrhosis was diagnosed based on clinical features, history of heavy alcohol consumption, laboratory tests and abdominal ultrasonography. The control group consisted of 20 healthy individuals without liver disease who did not abuse alcohol. The serum afamin and adropin concentrations were determined using ELISA kits. Results: The concentration of afamin was found to be significantly lower in pati...
Father Damien de Veuster, or Saint Damien of Molokai (1840-1889), was one of the pioneers of the ... more Father Damien de Veuster, or Saint Damien of Molokai (1840-1889), was one of the pioneers of the holistic approach to care provision for leprosy patients and contributed to the overcoming of the patients' social stigmatization. He devoted his life to the lepers living in America's only leper colony, on the Hawaiian island of Molokai, where people with leprosy were required to live under government-sanctioned medical quarantine. Father Damien gained practical skills in caring for the sick, eagerly learning wound cleansing, bandaging techniques, and drug administration from a nurse. Mahatma Gandhi said that Father Damien's work had inspired his own social campaigns in India.
Pielegniarstwo XXI wieku / Nursing in the 21st Century
Trusting the medical staff, especially the doctor is a fundamental part of the success of the tre... more Trusting the medical staff, especially the doctor is a fundamental part of the success of the treatment process. Appropriate level of trust in a doctor-patient relationship affects the patient’s compliance with the physician’s recommendations and motivates patient to fight the disease. Over the last few years, numerous studies have been conducted on the level of trust in medical staff, especially doctors.The aim of this study is to present reports on research on patients’ trust in doctors of various specialties. The work will be done in the form of analysis of literature, including statistical data, scientific papers and professional literature.Discussed topic has been raised in various countries, such as Poland, the United Kingdom, Nigeria, China. Presented overview of the work of research shows that the level of trust in the doctors of various specialties is unequal.It is extremely important that the analyzes are conducted on the topic, and as a consequence some appropriate measur...
The aim of this study was to determine if altered levels of selected trace elements manifest them... more The aim of this study was to determine if altered levels of selected trace elements manifest themselves during chronic depression. To identify elements strongly associated with chronic depression, relationships between the elemental contents of hair and nails and the interelement correlations were checked. Inductively coupled plasma mass spectrometry and ion chromatography were used to evaluate the contents of Zn, Cu, Co, Pb, Mn, and Fe in hair and nail samples from a total of 415 subjects (295 patients and 120 healthy volunteers). The study included logistic regression models to predict the probability of chronic depression. To investigate possible intercorrelations among the studied elements, the scaled principal component analysis was used. The research has revealed differences in TE levels in the group of depressed men and women in comparison to the healthy subjects. Statistically significant differences in both hair and nails contents of several elements were observed. Our stud...
2021 marks the 50th anniversary of the death of Jakub Rothfeld-Rostowski, an eminent neurologist,... more 2021 marks the 50th anniversary of the death of Jakub Rothfeld-Rostowski, an eminent neurologist, academic teacher, military doctor and amateur sculptor (Fig. 1) [1, 2]. His experimental studies and clinical observations, made before World War II, contributed to the development of knowledge and differential diagnosis of extrapyramidal syndromes, “gelolepsy” and “orgasmolepsy” [1, 3, 4]. He related the flexion reflex (Balduzzi-Rothfeld sign), described in 1926 by the Italian psychiatrist Ottorino Balduzzi (1897–1964), with the diagnosis of the location of brain tumors [5, 6]. Jakub Rothfeld-Rostowski was born into a Jewish family on February 4, 1884 in Bukachivtsy which belonged to Austro-Hungarian Empire (eastern Poland between the world wars, western Ukraine today). He was the son of Mojżesz Rotfeld and Lea nee Broder. After graduating from gymnasium in Lviv, he studied medicine at the Faculty of Medicine at the University of Lviv [2]. He obtained his doctor’s degree in medicine on March 31, 1909. In 1910, he became an assistant in the neurological outpatient clinic headed by Henryk Blumenstok-Halban (1870–1933). Before the outbreak of World War I, he worked in neurological clinics in Vienna and Hamburg. Rothfeld took an active part in neurological conferences–he gave lectures at the Congress of Neurologists in Crakow in 1912, and the following year in Wroclaw and Ghent. After the outbreak of World War I in 1914, he was called up to the Austrian Army and worked as a neurologist in military hospitals. After the end of hostilities, he returned to clinical and scientific work at the Institute of Physiology at the University of Lviv. He obtained his habilitation in 1919 on the basis of the dissertation “On the influence of the frontal lobe on motor reactions from the vestibular ear organ” [2]. After the restoration of Polish statehood, he joined the Polish Army, where he was promoted to the rank of major in the corps of medical sanitary officers. In 1920, he took part, as a doctor, in the Polish-Soviet War. He went to the army reserve in 1921. From that time, Rothfeld worked in the Department of Neurology of the University of Lviv, established by Blumenstok-Halban as a professor assistant. He became a titular professor of the Faculty of Medicine at the Jan Kazimierz University in Lviv in 1928. From 1933 to 1936, he headed the Clinic of Neurology [1, 2]. Shortly, before the outbreak of World War II, he finished writing a neurology textbook, publication of which was thwarted by the war. In 1939, as a military doctor, he took part in the first stage of World War II. After the defeat of the Polish army in the fight against the Nazi invaders, he managed to flee via Hungary to France, where he worked as a neurologist in a military hospital. In June 1940, after the Third Reich’s aggression against France, Rothfeld evacuated to Great Britain. From 1941, he headed the department of neurology in a military hospital in Scotland. Then, he changed his name to Rostowski [2]. He was a member of the Health Committee at the Ministry of Labor and Social Welfare of the Polish Government in London. He was a professor of neurology (from March 1941) and the Dean (1946–1949) of the Polish School of Medicine at the University of Edinburgh. Rothfeld-Rostowski did not return to Poland after World War II. In 1949–54, he worked as a consultant in the Department of Psychiatry of the Royal Edinburgh Hospital [1, 2]. In 1966, Rothfeld-Rostowski received an honorary degree of Doctor of Laws (LL.D.) of Alma Mater Edinburgensis. In the post-war period, he started carving. His works have been exhibited in Edinburgh and London. His sculpture "Their last Prayer at Belsen Camp" referring to the suffering of prisoners of the German Nazi concentration camps, was exhibited at the Royal Scottich Academy [1]. His wife * Jarosław Sak jareksak@tlen.pl
Artificial intelligence (AI) as a branch of computer science, the purpose of which is to imitate ... more Artificial intelligence (AI) as a branch of computer science, the purpose of which is to imitate thought processes, learning abilities and knowledge management, finds more and more applications in experimental and clinical medicine. In recent decades, there has been an expansion of AI applications in biomedical sciences. The possibilities of artificial intelligence in the field of medical diagnostics, risk prediction and support of therapeutic techniques are growing rapidly. The aim of the article is to analyze the current use of AI in nutrients science research. The literature review was conducted in PubMed. A total of 399 records published between 1987 and 2020 were obtained, of which, after analyzing the titles and abstracts, 261 were rejected. In the next stages, the remaining records were analyzed using the full-text versions and, finally, 55 papers were selected. These papers were divided into three areas: AI in biomedical nutrients research (20 studies), AI in clinical nutrie...
International Journal of Environmental Research and Public Health
In view of previous reports, it is important to determine the relationship between liver function... more In view of previous reports, it is important to determine the relationship between liver function and the level of fluoride in the serum. The aim of this study was to investigate serum concentrations of fluoride in 72 patients with alcoholic liver cirrhosis, living in the region of Lublin (Eastern Poland) divided based on the severity of disease according to the Child-Turcotte-Pugh criteria. Higher plasma fluoride concentrations were associated with changes in liver related parameters. In all groups of analyzed patients with different stages of alcoholic liver cirrhosis, elevated levels of plasma fluoride and increased activities of both alanine aminotransferase (ALT) and total bilirubin concentration were shown.
Introduction: Liver cirrhosis develops in about 10% of alcohol abusers. To date, a number of cell... more Introduction: Liver cirrhosis develops in about 10% of alcohol abusers. To date, a number of cells and cytokines have been identified, which are involved in induction of liver fibrotic processes. Nevertheless, the pathogenesis of liver cirrhosis has not been fully elucidated. The aim of the present study was to determine serum concentrations of afamin and adropin in patients with alcoholic liver cirrhosis and to define their correlation with the stage of disease. Materials and methods: The study included 99 patients with alcoholic cirrhosis from the region of Lublin, (Eastern Poland). Liver cirrhosis was diagnosed based on clinical features, history of heavy alcohol consumption, laboratory tests and abdominal ultrasonography. The control group consisted of 20 healthy individuals without liver disease who did not abuse alcohol. The serum afamin and adropin concentrations were determined using ELISA kits. Results: The concentration of afamin was found to be significantly lower in pati...
Father Damien de Veuster, or Saint Damien of Molokai (1840-1889), was one of the pioneers of the ... more Father Damien de Veuster, or Saint Damien of Molokai (1840-1889), was one of the pioneers of the holistic approach to care provision for leprosy patients and contributed to the overcoming of the patients' social stigmatization. He devoted his life to the lepers living in America's only leper colony, on the Hawaiian island of Molokai, where people with leprosy were required to live under government-sanctioned medical quarantine. Father Damien gained practical skills in caring for the sick, eagerly learning wound cleansing, bandaging techniques, and drug administration from a nurse. Mahatma Gandhi said that Father Damien's work had inspired his own social campaigns in India.
Pielegniarstwo XXI wieku / Nursing in the 21st Century
Trusting the medical staff, especially the doctor is a fundamental part of the success of the tre... more Trusting the medical staff, especially the doctor is a fundamental part of the success of the treatment process. Appropriate level of trust in a doctor-patient relationship affects the patient’s compliance with the physician’s recommendations and motivates patient to fight the disease. Over the last few years, numerous studies have been conducted on the level of trust in medical staff, especially doctors.The aim of this study is to present reports on research on patients’ trust in doctors of various specialties. The work will be done in the form of analysis of literature, including statistical data, scientific papers and professional literature.Discussed topic has been raised in various countries, such as Poland, the United Kingdom, Nigeria, China. Presented overview of the work of research shows that the level of trust in the doctors of various specialties is unequal.It is extremely important that the analyzes are conducted on the topic, and as a consequence some appropriate measur...
The aim of this study was to determine if altered levels of selected trace elements manifest them... more The aim of this study was to determine if altered levels of selected trace elements manifest themselves during chronic depression. To identify elements strongly associated with chronic depression, relationships between the elemental contents of hair and nails and the interelement correlations were checked. Inductively coupled plasma mass spectrometry and ion chromatography were used to evaluate the contents of Zn, Cu, Co, Pb, Mn, and Fe in hair and nail samples from a total of 415 subjects (295 patients and 120 healthy volunteers). The study included logistic regression models to predict the probability of chronic depression. To investigate possible intercorrelations among the studied elements, the scaled principal component analysis was used. The research has revealed differences in TE levels in the group of depressed men and women in comparison to the healthy subjects. Statistically significant differences in both hair and nails contents of several elements were observed. Our stud...
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