Fluorinated compounds are an important motif, particularly in pharmaceuticals, as one-third of th... more Fluorinated compounds are an important motif, particularly in pharmaceuticals, as one-third of the top performing drugs have fluorine in their structures. Fluorinated biaryls also have numerous applications in areas such as material science, agriculture, crystal engineering, supramolecular chemistry, etc. Thus, the development of new synthetic routes to fluorinated chemical compounds is an important area of current research. One promising method is the borylation of suitable precursors to generate fluorinated aryl boronates as versatile building blocks for organic synthesis. Chapter 1 In this chapter, the latest developments in the synthesis, stability issues, and applications of fluorinated aryl boronates in organic synthesis are reviewed. The catalytic synthesis of fluorinated aryl boronates using different methods, such as C–H, C–F, and C–X (X = Cl, Br, I, OTf) borylations are discussed. Further studies covering instability issues of the fluorinated boronate derivatives, which ar...
α-Amino cyclic boronates were synthesized from readily available salicylaldehydes, amines, and B2... more α-Amino cyclic boronates were synthesized from readily available salicylaldehydes, amines, and B2(OH)4. The process can be run at room temperature in ethanol, does not require catalysts or additives, and scale up and purification are easy.
Sifat semikonduktor yang dimiliki silikon memungkinkan terjadinya aliran listrik melalui suatu sa... more Sifat semikonduktor yang dimiliki silikon memungkinkan terjadinya aliran listrik melalui suatu sambungan P-N. Salah satu modifikasi untuk meningkatkan tegangan serta arus listrik pada sel surya adalah dengan menambahkan suatu zat warna seperti xantofil pada permukaannya. Penelitian ini bertujuan untuk mengetahui pengaruh pelapisan xantolfil dengan konsentrasi (10%, 20% dan 30%) pada sel surya terhadap tegangan listrik serta arus listrik yang dihasilkan. Metode preparasi sel surya adalah metode difusi yaitu menempelkan padatan fosfor secara langsung pada silikon tipe-P pada suhu 900°C. Peningkatan arus dan tegangan listrik pada permukaan sel surya yang dilapisi xantofil diukur menggunakan avometer. Dari hasil penelitian didapatkan kenaikan tegangan listrik maksimum sebesar 2,38% dan kenaikan arus listrik maksimum sebesar 7,53%.
A combination of copper iodide and phenanthroline as the
ligand is an efficient catalyst for Suzu... more A combination of copper iodide and phenanthroline as the ligand is an efficient catalyst for Suzuki-Miyaura cross-coupling of highly fluorinated boronate esters (aryl Bpin) with aryl iodides and bromides to generate fluorinated biaryls in good to excellent yields. This method represents a nice alternative to traditional cross-coupling methods which require palladium catalysts and stoichiometric amounts of silver oxide. We note that π···π stacking interactions dominate the molecular packing in the partly fluorinated biaryl crystals investigated herein. They are present either between the arene and perfluoroarene, or solely between arenes or perfluoroarenes, respectivel
Fluorinated compounds are an important motif, particularly in pharmaceuticals, as one-third of th... more Fluorinated compounds are an important motif, particularly in pharmaceuticals, as one-third of the top performing drugs have fluorine in their structures. Fluorinated biaryls also have numerous applications in areas such as material science, agriculture, crystal engineering, supramolecular chemistry, etc. Thus, the development of new synthetic routes to fluorinated chemical compounds is an important area of current research. One promising method is the borylation of suitable precursors to generate fluorinated aryl boronates as versatile building blocks for organic synthesis. Chapter 1 In this chapter, the latest developments in the synthesis, stability issues, and applications of fluorinated aryl boronates in organic synthesis are reviewed. The catalytic synthesis of fluorinated aryl boronates using different methods, such as C–H, C–F, and C–X (X = Cl, Br, I, OTf) borylations are discussed. Further studies covering instability issues of the fluorinated boronate derivatives, which ar...
α-Amino cyclic boronates were synthesized from readily available salicylaldehydes, amines, and B2... more α-Amino cyclic boronates were synthesized from readily available salicylaldehydes, amines, and B2(OH)4. The process can be run at room temperature in ethanol, does not require catalysts or additives, and scale up and purification are easy.
Sifat semikonduktor yang dimiliki silikon memungkinkan terjadinya aliran listrik melalui suatu sa... more Sifat semikonduktor yang dimiliki silikon memungkinkan terjadinya aliran listrik melalui suatu sambungan P-N. Salah satu modifikasi untuk meningkatkan tegangan serta arus listrik pada sel surya adalah dengan menambahkan suatu zat warna seperti xantofil pada permukaannya. Penelitian ini bertujuan untuk mengetahui pengaruh pelapisan xantolfil dengan konsentrasi (10%, 20% dan 30%) pada sel surya terhadap tegangan listrik serta arus listrik yang dihasilkan. Metode preparasi sel surya adalah metode difusi yaitu menempelkan padatan fosfor secara langsung pada silikon tipe-P pada suhu 900°C. Peningkatan arus dan tegangan listrik pada permukaan sel surya yang dilapisi xantofil diukur menggunakan avometer. Dari hasil penelitian didapatkan kenaikan tegangan listrik maksimum sebesar 2,38% dan kenaikan arus listrik maksimum sebesar 7,53%.
A combination of copper iodide and phenanthroline as the
ligand is an efficient catalyst for Suzu... more A combination of copper iodide and phenanthroline as the ligand is an efficient catalyst for Suzuki-Miyaura cross-coupling of highly fluorinated boronate esters (aryl Bpin) with aryl iodides and bromides to generate fluorinated biaryls in good to excellent yields. This method represents a nice alternative to traditional cross-coupling methods which require palladium catalysts and stoichiometric amounts of silver oxide. We note that π···π stacking interactions dominate the molecular packing in the partly fluorinated biaryl crystals investigated herein. They are present either between the arene and perfluoroarene, or solely between arenes or perfluoroarenes, respectivel
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Papers by Yudha Prawira Budiman
ligand is an efficient catalyst for Suzuki-Miyaura cross-coupling
of highly fluorinated boronate esters (aryl Bpin) with aryl
iodides and bromides to generate fluorinated biaryls in good to
excellent yields. This method represents a nice alternative to
traditional cross-coupling methods which require palladium
catalysts and stoichiometric amounts of silver oxide. We note
that π···π stacking interactions dominate the molecular packing
in the partly fluorinated biaryl crystals investigated herein. They
are present either between the arene and perfluoroarene, or
solely between arenes or perfluoroarenes, respectivel
ligand is an efficient catalyst for Suzuki-Miyaura cross-coupling
of highly fluorinated boronate esters (aryl Bpin) with aryl
iodides and bromides to generate fluorinated biaryls in good to
excellent yields. This method represents a nice alternative to
traditional cross-coupling methods which require palladium
catalysts and stoichiometric amounts of silver oxide. We note
that π···π stacking interactions dominate the molecular packing
in the partly fluorinated biaryl crystals investigated herein. They
are present either between the arene and perfluoroarene, or
solely between arenes or perfluoroarenes, respectivel