Location via proxy:   [ UP ]  
[Report a bug]   [Manage cookies]                
skip to main content
10.1145/1141277.1141313acmconferencesArticle/Chapter ViewAbstractPublication PagessacConference Proceedingsconference-collections
Article

PackageBLAST: an adaptive multi-policy grid service for biological sequence comparison

Published: 23 April 2006 Publication History

Abstract

In this paper, we propose an adaptive task allocation framework to perform BLAST searches in a grid environment against sequence database segments. The framework, called PackageBLAST, provides an infrastructure to choose or incorporate task allocation strategies. Furthermore, we propose a mechanism to compute grid nodes execution weight, adapting the chosen allocation policy to the current computational power of the nodes. Our results present very good speedups and also show that no single allocation strategy is able to achieve the lowest execution times for all scenarios.

References

[1]
S. F. Altschul, W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. A basic local alignment search tool. Journal of Molecular Biology, 215:403--410, 1990.
[2]
A. Darling, L. Carey, and W. Feng. The design, implementation, and evaluation of mpiblast. 4th International Conference on Linux Clusters, 2003.
[3]
S. F. A. et al. Gapped blast and psi-blast: a new generation of protein database search programs. Nucleic Acids Research, 25(17):3389--3402, 1997.
[4]
I. Foster and C. Kesselman. Globus: A metacomputing infrastructure toolkit. International Journal of Supercomputer Applications, 11(2):115--128, 1997.
[5]
I. Foster and C. Kesselman. The Grid: Blueprint of a Future Computing Infrastructure. Morgan-Kauffman, 1999.
[6]
W. Gish. Washington university blast. http://blast.wustl.edu, 1996--2002.
[7]
D. Gusfield. Algorithms on Strings, Trees and Sequences. Cambridge University Press, 1997.
[8]
S. F. Hummel, E. Schonberg, and L. E. Flynn. Factoring: A method for scheduling parallel loops. Communications of the ACM, 35(8):90--101, 1992.
[9]
A. Krishnan. Gridblast: High throughput blast on the grid. Symposium on Biocomputing, January 2003.
[10]
D. Peng., W. Yan, and Z. Lei. Parallelization of blast++. Technical report, Singapore-MIT, 2004.
[11]
C. D. Polychronopoulos and D. J. Kuck. Guided self-scheduling: A practical scheduling scheme for parallel supercomputers. IEEE Transactions on Computers, 36(12): 1425--1439, Dec. 1987.
[12]
M. K. Satish and R. R. Joshi. Gbtk: A toolkit for grid implementation of blast. 7th International Conference HPCAsia, pages 378--382, 2004.
[13]
G. Shao. Adaptive Scheduling of Master/Worker Applications on Distributed Computational Resources. PhD thesis, Univ. California at San Diego, 2001.
[14]
T. Smith and M. Waterman. Identification of common molecular subsequences. J. Mol. Biol., 147:195--197, 1981.
[15]
P. Tang and P. C. Yew. Processor self-scheduling for multiple nested parallel loops. In Int. Conf. on Parallel Processing (ICPP), pages 528--535, 1986.
[16]
T. H. Tzen and L. M. Ni. Trapezoidal self-scheduling: A practical scheme for parallel compilers. IEEE Transactions on Parallel and Distributed Systems, 4(1):87--98, Jan. 1993.

Cited By

View all
  • (2009)BLAST Application with Data-Aware Desktop Grid MiddlewareProceedings of the 2009 9th IEEE/ACM International Symposium on Cluster Computing and the Grid10.1109/CCGRID.2009.91(284-291)Online publication date: 18-May-2009
  • (2006)An Extensible Resource Discovery Mechanism for Grid Computing EnvironmentsProceedings of the Sixth IEEE International Symposium on Cluster Computing and the Grid10.1109/CCGRID.2006.16(115-122)Online publication date: 16-May-2006

Recommendations

Comments

Information & Contributors

Information

Published In

cover image ACM Conferences
SAC '06: Proceedings of the 2006 ACM symposium on Applied computing
April 2006
1967 pages
ISBN:1595931082
DOI:10.1145/1141277
Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

Sponsors

Publisher

Association for Computing Machinery

New York, NY, United States

Publication History

Published: 23 April 2006

Permissions

Request permissions for this article.

Check for updates

Author Tags

  1. bioinformatics
  2. grid computing
  3. task allocation

Qualifiers

  • Article

Conference

SAC06
Sponsor:

Acceptance Rates

Overall Acceptance Rate 1,650 of 6,669 submissions, 25%

Upcoming Conference

SAC '25
The 40th ACM/SIGAPP Symposium on Applied Computing
March 31 - April 4, 2025
Catania , Italy

Contributors

Other Metrics

Bibliometrics & Citations

Bibliometrics

Article Metrics

  • Downloads (Last 12 months)0
  • Downloads (Last 6 weeks)0
Reflects downloads up to 23 Dec 2024

Other Metrics

Citations

Cited By

View all
  • (2009)BLAST Application with Data-Aware Desktop Grid MiddlewareProceedings of the 2009 9th IEEE/ACM International Symposium on Cluster Computing and the Grid10.1109/CCGRID.2009.91(284-291)Online publication date: 18-May-2009
  • (2006)An Extensible Resource Discovery Mechanism for Grid Computing EnvironmentsProceedings of the Sixth IEEE International Symposium on Cluster Computing and the Grid10.1109/CCGRID.2006.16(115-122)Online publication date: 16-May-2006

View Options

Login options

View options

PDF

View or Download as a PDF file.

PDF

eReader

View online with eReader.

eReader

Media

Figures

Other

Tables

Share

Share

Share this Publication link

Share on social media