research-article

Facilitating medication adherence and eliminating therapeutic inertia using wireless technology: proof of concept findings with uncontrolled hypertensives and kidney transplant recipients

Authors:

John W. McGillicuddy,

Mathew J. Gregoski,

Brenda M. Brunner-Jackson,

Ana K. Weiland,

Sachin K. Patel,

Rebecca A. Rock,

Eveline M. Treiber,

Lydia K. Davidson,

Frank A. TreiberAuthors Info & Claims

WH '12: Proceedings of the conference on Wireless Health

Article No.: 12, Pages 1 - 9

https://doi.org/10.1145/2448096.2448108

Published: 23 October 2012 Publication History

Abstract

Effective and efficient management of chronic illness remains a significant clinical problem. To improve chronic illness management, two obstacles that must be overcome are patient non-adherence to medication regimens and provider therapeutic inertia (failure to respond in timely manner to clinical data). Using an iterative approach, behavioral theory was used to develop a mobile health (mHealth) medication and blood pressure self-management system that was patient and provider centered. Electronic medication trays provided reminder signals and smart phone text messages reminded patients to measure blood pressures using a Bluetooth-enabled monitor. Patients received mobile phone-delivered personalized motivational and reinforcement messages based upon adherence levels to these regimens. Two 3-month proof of concept randomized control trials were conducted with 2 patient groups; 1) Hispanics with uncontrolled essential hypertension (n=6), and 2) patients with hypertension after kidney transplantation. (n=6). Hispanic patients who received the mHealth intervention all exhibited significant improvements in both medication adherence and reductions in resting and 24-hour blood pressures during the trial and at 3-month follow-up, as compared to the control group.

The still ongoing kidney transplant trial has shown that recipients randomized to the mHealth intervention have demonstrated significant improvements in medication adherence and reduced blood pressure two months into the trial. Following completion of both studies, patient and provider focus groups will allow further iterative refinement of the mHealth system and a feasibility trial of larger scale and longer duration.

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Cited By

Senteio CMurdock P(2022)The Efficacy of Health Information Technology in Supporting Health Equity for Black and Hispanic Patients With Chronic Diseases: Systematic ReviewJournal of Medical Internet Research10.2196/2212424:4(e22124)Online publication date: 4-Apr-2022
https://doi.org/10.2196/22124
Mellon LDoyle FHickey AWard Kde Freitas DMcCormick PO'Connell OConlon P(2022)Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipientsCochrane Database of Systematic Reviews10.1002/14651858.CD012854.pub22022:9Online publication date: 12-Sep-2022
https://doi.org/10.1002/14651858.CD012854.pub2
Campbell ZDawson JKirkendall SMcCaffery KJansen JCampbell KLee VWebster A(2022)Interventions for improving health literacy in people with chronic kidney diseaseCochrane Database of Systematic Reviews10.1002/14651858.CD012026.pub22022:12Online publication date: 6-Dec-2022
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Index Terms

Facilitating medication adherence and eliminating therapeutic inertia using wireless technology: proof of concept findings with uncontrolled hypertensives and kidney transplant recipients
1. Applied computing
  1. Life and medical sciences
    1. Consumer health
    2. Health informatics

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cover image ACM Other conferences

WH '12: Proceedings of the conference on Wireless Health

October 2012

117 pages

ISBN:9781450317603

DOI:10.1145/2448096

General Chairs:
William Kaiser
University of California, Los Angeles
,
Robert McCray
Wireless-Life Sciences Alliance

Copyright © 2012 Authors.

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WLSA: Wireless-Life Sciences Alliance

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SIGMOBILE: ACM Special Interest Group on Mobility of Systems, Users, Data and Computing

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Association for Computing Machinery

New York, NY, United States

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Published: 23 October 2012

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WH '12: Wireless Health 2012

October 23 - 25, 2012

California, San Diego

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Cited By

Senteio CMurdock P(2022)The Efficacy of Health Information Technology in Supporting Health Equity for Black and Hispanic Patients With Chronic Diseases: Systematic ReviewJournal of Medical Internet Research10.2196/2212424:4(e22124)Online publication date: 4-Apr-2022
https://doi.org/10.2196/22124
Mellon LDoyle FHickey AWard Kde Freitas DMcCormick PO'Connell OConlon P(2022)Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipientsCochrane Database of Systematic Reviews10.1002/14651858.CD012854.pub22022:9Online publication date: 12-Sep-2022
https://doi.org/10.1002/14651858.CD012854.pub2
Campbell ZDawson JKirkendall SMcCaffery KJansen JCampbell KLee VWebster A(2022)Interventions for improving health literacy in people with chronic kidney diseaseCochrane Database of Systematic Reviews10.1002/14651858.CD012026.pub22022:12Online publication date: 6-Dec-2022
https://doi.org/10.1002/14651858.CD012026.pub2
Cruz-Martínez RWentzel JBente BSanderman Rvan Gemert-Pijnen J(2021)Towards Value Sensitive Design of eHealth Technologies to Support Self-Management of Cardiovascular Diseases: Content Analysis (Preprint)JMIR Cardio10.2196/31985Online publication date: 12-Jul-2021
https://doi.org/10.2196/31985
Cruz-Martínez RWentzel JAsbjørnsen RNoort Pvan Niekerk JSanderman Rvan Gemert-Pijnen L(2019)Supporting Self-Management of Cardiovascular Diseases Through Remote Monitoring Technologies: Metaethnography Review of Frameworks, Models, and Theories Used in Research and Development (Preprint)Journal of Medical Internet Research10.2196/16157Online publication date: 6-Sep-2019
https://doi.org/10.2196/16157
McGillicuddy JChandler JSox LMueller MNemeth LBaliga PTreiber F(2019)“Smartphone Medication Adherence Saves Kidneys” for Kidney Transplantation Recipients: Protocol for a Randomized Controlled TrialJMIR Research Protocols10.2196/133518:6(e13351)Online publication date: 21-Jun-2019
https://doi.org/10.2196/13351
Stevenson JCampbell ZWebster AChow CTong ACraig JCampbell KLee V(2019)eHealth interventions for people with chronic kidney diseaseCochrane Database of Systematic Reviews10.1002/14651858.CD012379.pub2Online publication date: 6-Aug-2019
https://doi.org/10.1002/14651858.CD012379.pub2
Xiong SBerkhouse HSchooler MPu WSun AGong EYan L(2018)Effectiveness of mHealth Interventions in Improving Medication Adherence Among People with Hypertension: a Systematic ReviewCurrent Hypertension Reports10.1007/s11906-018-0886-720:10Online publication date: 7-Aug-2018
https://doi.org/10.1007/s11906-018-0886-7
Fleming JMcGillicuddy JTreiber F(2018)Mobile Health Technology in TransplantationTechnological Advances in Organ Transplantation10.1007/978-3-319-62142-5_3(63-85)Online publication date: 24-May-2018
https://doi.org/10.1007/978-3-319-62142-5_3
Davidson TMcGillicuddy JMueller MBrunner-Jackson BFavella AAnderson ATorres MRuggiero KTreiber F(2015)Evaluation of an mHealth Medication Regimen Self-Management Program for African American and Hispanic Uncontrolled HypertensivesJournal of Personalized Medicine10.3390/jpm50403895:4(389-405)Online publication date: 17-Nov-2015
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