In India, a study was undertaken on different serum lipids in women using oral contraceptive pill... more In India, a study was undertaken on different serum lipids in women using oral contraceptive pills for more than three months. 40 women attending a family planning center who were of proven fertility, ages ranging from 15-40 years, parity 1-6 and had used oral contraceptive for at least 3 months were studied. The cases were divided into 3 groups according to duration of pill use which varies from 6 months-18 months. Estimation of total lipid and fractionate cholesterol, phospholipids and triglycerides were done by thin layer paper chromatogrpahy. There was an increase in serum triglyceride level of 32% which is in agreement with other work and the level increased gradually as the duration of therapy increased. A significant increase in total lipids above control values which were present during first 3 cycles of use increased further during subsequent use. Rise in total lipids and cholesterol is unexpected because if the pills used are strongly estrogenic then the cholesterol level should decrease. However it has been pointed out by several workers that when estrogen is combined with progestogen, the metabolic effects of estrogen are unpredictable. Mean serum cholesterol level showed no significant changes up to 6 cycles, but showed significant rise as compared to control levels from 6-12 cycles. The relationship of these changes to atherosclerosis is not yet established and such changes cannot be dismissed as harmless.
Asia-Oceania journal of obstetrics and gynaecology, May 24, 2010
Irregular growth of bone was seen in the endometrial tissue after h‐sterectom‐ from a fortear old... more Irregular growth of bone was seen in the endometrial tissue after h‐sterectom‐ from a fortear old woman, four ‐ears after a therapeutic abortion. Implantation of fetal remnants into the uterine wall at the time of instrumentation has been considered as a source of heterotopic tissue.
Journal of Obstetrics and Gynaecology Research, Oct 1, 1996
In a randomized controlled trial 201 healthy nulliparous women were randomly allocated by means o... more In a randomized controlled trial 201 healthy nulliparous women were randomly allocated by means of a computer generated randomization list. From 20 weeks of gestation until delivery they received either 2 g of oral elemental calcium (n = 103) per day or an identical placebo (n = 98). Eleven women (5.47%) were lost to follow-up after randomization. The study groups were very similar at the time of randomization; with respect to several clinical and demographic variables. Treatment compliance was very similar in both groups as was determined by pill count. The rate of pregnancy induced hypertension was lower in the calcium group than in the placebo group 8.24%; vs 29.03%; (RR = 0.28; 95% CI 0.14-0.59). The incidence of gestational hypertension was 6.18% in the calcium group and 17.20% in the placebo group (RR = 0.28; 95% CI 0.08-0.80), and the incidence of preeclampsia was 2.06% in the calcium group and 11.82% in the placebo group (RR = 0.13; 95% CI 0.01-0.64). In conclusion calcium supplementation given in pregnancy to nulliparous women reduces the incidence of pregnancy induced hypertension.
Detailed assessments of mortality patterns, particularly age-specific mortality, represent a cruc... more Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to development status can identify exemplars for best practice. To accomplish this, the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) estimated age-specific and sex-specific all-cause mortality between 1970 and 2016 for 195 countries and territories and at the subnational level for the five countries with a population greater than 200 million in 2016. We have evaluated how well civil registration systems captured deaths using a set of demographic methods called death distribution methods for adults and from consideration of survey and census data for children younger than 5 years. We generated an overall assessment of completeness of registration of deaths by dividing registered deaths in each location-year by ...
Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and year... more Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013. Estimates were calculated for disease and injury incidence, prevalence, and YLDs using GBD 2010 methods with some important refinements. Results for incidence of acute disorders and prevalence of chronic disorders are new additions to the analysis. Key improvements include expansion to the cause and sequelae list, updated systematic reviews, use of detailed injury codes, improvements to the Bayesian meta-regression method (DisMod-MR), and use of severity splits for various causes. An index of data representativeness, showing data availability, was calculated for each cause and impairment during three periods globally...
The prescription patterns of obstetric ward after confinement were studied. Perinatal prescriptio... more The prescription patterns of obstetric ward after confinement were studied. Perinatal prescriptions (1748) were therapeutically audited to find number of drugs per prescriptions, number in different categories, use of banned/generic names, dosage form, frequency, duration of treatment. Drugs were prescribed by generic name (53%), dosage form (90%), frequency of drug intake (96.77%) was in majority of prescription. The duration(97%) & dosage in recommended unit (67.04%) were not mentioned. Drugs were changed in (36.2%) cases & poly pharmacy was widely seen except in certain cases where the prescription was rational
The domestic violence is an unpleasant subject and one that many physicians do not recognize or a... more The domestic violence is an unpleasant subject and one that many physicians do not recognize or acknowledge, because physical violence is disproportionately directed against women.It is important for obstetrician/gynecologist to be aware of the extent of the problem, which has been termed wife beating or battering.
The aim was to provide an overview of the magnitude of the public health burden associated with i... more The aim was to provide an overview of the magnitude of the public health burden associated with inpatient care for pregnancy complications. 1700 delivered women were interviewed in postnatal ward for antenatal hospitalization, hospital stay in days and diagnosis for admission. For every 100 births there were 22.94% (95% CI 0.21-0.25) antenatal hospitalization for pregnancy complications requiring 18,221 days of care. Most prevalent diagnosis for hospitalization was Pregnancy induced hypertension, Preterm labor, PROM, Pyrexia, anemia and cardiac disease complicating pregnancy. 18 women (4.61%) required readmission for pre term labor, Pregnancy induced hypertension and pyrexia.
In India, a study was undertaken on different serum lipids in women using oral contraceptive pill... more In India, a study was undertaken on different serum lipids in women using oral contraceptive pills for more than three months. 40 women attending a family planning center who were of proven fertility, ages ranging from 15-40 years, parity 1-6 and had used oral contraceptive for at least 3 months were studied. The cases were divided into 3 groups according to duration of pill use which varies from 6 months-18 months. Estimation of total lipid and fractionate cholesterol, phospholipids and triglycerides were done by thin layer paper chromatogrpahy. There was an increase in serum triglyceride level of 32% which is in agreement with other work and the level increased gradually as the duration of therapy increased. A significant increase in total lipids above control values which were present during first 3 cycles of use increased further during subsequent use. Rise in total lipids and cholesterol is unexpected because if the pills used are strongly estrogenic then the cholesterol level should decrease. However it has been pointed out by several workers that when estrogen is combined with progestogen, the metabolic effects of estrogen are unpredictable. Mean serum cholesterol level showed no significant changes up to 6 cycles, but showed significant rise as compared to control levels from 6-12 cycles. The relationship of these changes to atherosclerosis is not yet established and such changes cannot be dismissed as harmless.
Asia-Oceania journal of obstetrics and gynaecology, May 24, 2010
Irregular growth of bone was seen in the endometrial tissue after h‐sterectom‐ from a fortear old... more Irregular growth of bone was seen in the endometrial tissue after h‐sterectom‐ from a fortear old woman, four ‐ears after a therapeutic abortion. Implantation of fetal remnants into the uterine wall at the time of instrumentation has been considered as a source of heterotopic tissue.
Journal of Obstetrics and Gynaecology Research, Oct 1, 1996
In a randomized controlled trial 201 healthy nulliparous women were randomly allocated by means o... more In a randomized controlled trial 201 healthy nulliparous women were randomly allocated by means of a computer generated randomization list. From 20 weeks of gestation until delivery they received either 2 g of oral elemental calcium (n = 103) per day or an identical placebo (n = 98). Eleven women (5.47%) were lost to follow-up after randomization. The study groups were very similar at the time of randomization; with respect to several clinical and demographic variables. Treatment compliance was very similar in both groups as was determined by pill count. The rate of pregnancy induced hypertension was lower in the calcium group than in the placebo group 8.24%; vs 29.03%; (RR = 0.28; 95% CI 0.14-0.59). The incidence of gestational hypertension was 6.18% in the calcium group and 17.20% in the placebo group (RR = 0.28; 95% CI 0.08-0.80), and the incidence of preeclampsia was 2.06% in the calcium group and 11.82% in the placebo group (RR = 0.13; 95% CI 0.01-0.64). In conclusion calcium supplementation given in pregnancy to nulliparous women reduces the incidence of pregnancy induced hypertension.
Detailed assessments of mortality patterns, particularly age-specific mortality, represent a cruc... more Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to development status can identify exemplars for best practice. To accomplish this, the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) estimated age-specific and sex-specific all-cause mortality between 1970 and 2016 for 195 countries and territories and at the subnational level for the five countries with a population greater than 200 million in 2016. We have evaluated how well civil registration systems captured deaths using a set of demographic methods called death distribution methods for adults and from consideration of survey and census data for children younger than 5 years. We generated an overall assessment of completeness of registration of deaths by dividing registered deaths in each location-year by ...
Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and year... more Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013. Estimates were calculated for disease and injury incidence, prevalence, and YLDs using GBD 2010 methods with some important refinements. Results for incidence of acute disorders and prevalence of chronic disorders are new additions to the analysis. Key improvements include expansion to the cause and sequelae list, updated systematic reviews, use of detailed injury codes, improvements to the Bayesian meta-regression method (DisMod-MR), and use of severity splits for various causes. An index of data representativeness, showing data availability, was calculated for each cause and impairment during three periods globally...
The prescription patterns of obstetric ward after confinement were studied. Perinatal prescriptio... more The prescription patterns of obstetric ward after confinement were studied. Perinatal prescriptions (1748) were therapeutically audited to find number of drugs per prescriptions, number in different categories, use of banned/generic names, dosage form, frequency, duration of treatment. Drugs were prescribed by generic name (53%), dosage form (90%), frequency of drug intake (96.77%) was in majority of prescription. The duration(97%) & dosage in recommended unit (67.04%) were not mentioned. Drugs were changed in (36.2%) cases & poly pharmacy was widely seen except in certain cases where the prescription was rational
The domestic violence is an unpleasant subject and one that many physicians do not recognize or a... more The domestic violence is an unpleasant subject and one that many physicians do not recognize or acknowledge, because physical violence is disproportionately directed against women.It is important for obstetrician/gynecologist to be aware of the extent of the problem, which has been termed wife beating or battering.
The aim was to provide an overview of the magnitude of the public health burden associated with i... more The aim was to provide an overview of the magnitude of the public health burden associated with inpatient care for pregnancy complications. 1700 delivered women were interviewed in postnatal ward for antenatal hospitalization, hospital stay in days and diagnosis for admission. For every 100 births there were 22.94% (95% CI 0.21-0.25) antenatal hospitalization for pregnancy complications requiring 18,221 days of care. Most prevalent diagnosis for hospitalization was Pregnancy induced hypertension, Preterm labor, PROM, Pyrexia, anemia and cardiac disease complicating pregnancy. 18 women (4.61%) required readmission for pre term labor, Pregnancy induced hypertension and pyrexia.
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