Macroalgae Halimeda discoidea was studied for its bioactivities and characterization of the bioac... more Macroalgae Halimeda discoidea was studied for its bioactivities and characterization of the bioactive fraction was carried out. The antimicrobial activity of 8 extracts with different polarities (methanol, ethyl acetate, diethyl ether, butanol, hexane and chloroform) was started with the screening against 18 bacteria, three yeast and five fungi, through the disc diffusion method. The result revealed that hexane extract was the most active extract, followed by the ethyl acetate (Soxhlet) and chloroform extracts. Hexane extract was active against five Gram-positive and three Gram-negative bacteria and two yeasts
In the present time the medicinal plants are substantial sources of biologically active materials... more In the present time the medicinal plants are substantial sources of biologically active materials including phenolics and flavonoids which are a good antioxidant agent. Citrus. sinensis species are important because of their medicinal, traditional and economical uses. They are used in Sudan for treatment of various diseases traditionally. In this study the plant material was extracted with different solvents by using Soxhlet apparatus. Antioxidant activity; total phenolic; total flavonoid content; and brine shrimp lethality potential from C. sinensis methanol root extract was determined. Three fractions of the methanol extract of the root showed remarkable results in antioxidant activity, total phenolic, total flavonoid content and no genotoxic effect was observed. The total content of phenols and flavonoids of these fractions were strongly associated with the antioxidant activity. Generally, C. sinensis root can be used as source of natural antioxidant compounds, hence may also sup...
Abstract: The present study aims to study the antibacterial potentiality and phytochemistry const... more Abstract: The present study aims to study the antibacterial potentiality and phytochemistry constituents of hexane extract of Acanthophora spicifera from Malaysian water. It includes the evaluation of hexane extract for antibacterial activity using disc diffusion method, MIC, MBC and composition study using GC-MS analysis. The results revealed a potential antibacterial activity of hexane extract against MRSA and P. aeruginosa (27853) with low MICs of 0.125 and 0.50 mg/ml, respectively. To the best of our knowledge no details GC-MS analysis of volatile components of A. spicifera has been carried out from this local algae, eventhough details examination of fatty acids of A. spicifera from India has been performed. This prompted us to examine the preliminary phytochemical constituents of A. spicifera from Malaysian water. The GC-MS analysis revealed the presence of hydrocarbons, fatty acids and cholesterol. Oleic acid (14.58%) and n-hexadecanoic acid (24.73%) were the major components.
Biofouling is a phenomenon that describes the fouling organisms attached to man-made surfaces imm... more Biofouling is a phenomenon that describes the fouling organisms attached to man-made surfaces immersed in water over a period of time. It has emerged as a chronic problem to the oceanic industries, especially the shipping and aquaculture fields. The metal-containing coatings that have been used for many years to prevent and destroy biofouling are damaging to the ocean and many organisms. Therefore, this calls for the critical need of natural product-based antifoulants as a substitute for its toxic counterparts. In this study, the antibacterial and antibiofilm activities of the bioactive compounds of Pseudoalteromonas sp. IBRL PD4.8 have been investigated against selected fouling bacteria. The crude extract has shown strong antibacterial activity against five fouling bacteria, with inhibition zones ranging from 9.8 to 13.7 mm and minimal inhibitory concentrations of 0.13 to 8.0 mg/ml. Meanwhile, the antibiofilm study has indicated that the extract has attenuated the initial and pre-f...
Macroalgae Halimeda discoidea was studied for its bioactivities and characterization of the bioac... more Macroalgae Halimeda discoidea was studied for its bioactivities and characterization of the bioactive fraction was carried out. The antimicrobial activity of 8 extracts with different polarities (methanol, ethyl acetate, diethyl ether, butanol, hexane and chloroform) was started with the screening against 18 bacteria, three yeast and five fungi, through the disc diffusion method. The result revealed that hexane extract was the most active extract, followed by the ethyl acetate (Soxhlet) and chloroform extracts. Hexane extract was active against five Gram-positive and three Gram-negative bacteria and two yeasts
In the present time the medicinal plants are substantial sources of biologically active materials... more In the present time the medicinal plants are substantial sources of biologically active materials including phenolics and flavonoids which are a good antioxidant agent. Citrus. sinensis species are important because of their medicinal, traditional and economical uses. They are used in Sudan for treatment of various diseases traditionally. In this study the plant material was extracted with different solvents by using Soxhlet apparatus. Antioxidant activity; total phenolic; total flavonoid content; and brine shrimp lethality potential from C. sinensis methanol root extract was determined. Three fractions of the methanol extract of the root showed remarkable results in antioxidant activity, total phenolic, total flavonoid content and no genotoxic effect was observed. The total content of phenols and flavonoids of these fractions were strongly associated with the antioxidant activity. Generally, C. sinensis root can be used as source of natural antioxidant compounds, hence may also sup...
Abstract: The present study aims to study the antibacterial potentiality and phytochemistry const... more Abstract: The present study aims to study the antibacterial potentiality and phytochemistry constituents of hexane extract of Acanthophora spicifera from Malaysian water. It includes the evaluation of hexane extract for antibacterial activity using disc diffusion method, MIC, MBC and composition study using GC-MS analysis. The results revealed a potential antibacterial activity of hexane extract against MRSA and P. aeruginosa (27853) with low MICs of 0.125 and 0.50 mg/ml, respectively. To the best of our knowledge no details GC-MS analysis of volatile components of A. spicifera has been carried out from this local algae, eventhough details examination of fatty acids of A. spicifera from India has been performed. This prompted us to examine the preliminary phytochemical constituents of A. spicifera from Malaysian water. The GC-MS analysis revealed the presence of hydrocarbons, fatty acids and cholesterol. Oleic acid (14.58%) and n-hexadecanoic acid (24.73%) were the major components.
Biofouling is a phenomenon that describes the fouling organisms attached to man-made surfaces imm... more Biofouling is a phenomenon that describes the fouling organisms attached to man-made surfaces immersed in water over a period of time. It has emerged as a chronic problem to the oceanic industries, especially the shipping and aquaculture fields. The metal-containing coatings that have been used for many years to prevent and destroy biofouling are damaging to the ocean and many organisms. Therefore, this calls for the critical need of natural product-based antifoulants as a substitute for its toxic counterparts. In this study, the antibacterial and antibiofilm activities of the bioactive compounds of Pseudoalteromonas sp. IBRL PD4.8 have been investigated against selected fouling bacteria. The crude extract has shown strong antibacterial activity against five fouling bacteria, with inhibition zones ranging from 9.8 to 13.7 mm and minimal inhibitory concentrations of 0.13 to 8.0 mg/ml. Meanwhile, the antibiofilm study has indicated that the extract has attenuated the initial and pre-f...
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