I am a Professor of Chemistry, with research interests mainly in Organic Chemistry in the field of Synthesis of Natural Products with biological activity. Outside this main field, I also like to write computer programs in visual basic and visual c
Abstract A β-hydroxymethyl-γ-butyrolactone, which is a useful intermediate for the synthesis of s... more Abstract A β-hydroxymethyl-γ-butyrolactone, which is a useful intermediate for the synthesis of several natural products with biological activity, was synthesized with good yield and a reduced number of steps from simple commercially available starting materials. Model ...
ABSTRACT In the course of studies on the synthesis and chemistry of betweenanenes we have devised... more ABSTRACT In the course of studies on the synthesis and chemistry of betweenanenes we have devised a short route (Chart I) to symmetrical members of the family (e.g., 4) which we disclose herewith.
The organocerium compound derived from ester (I) readily reacts with symmetrical and unsymmetrica... more The organocerium compound derived from ester (I) readily reacts with symmetrical and unsymmetrical ketones to give γ-butyrolactones as main components and symmetrical diols such as (IV) as by-products.
ABSTRACT A method for the preparation of 3-substituted furans starting with the addition of bis(p... more ABSTRACT A method for the preparation of 3-substituted furans starting with the addition of bis(phenylthio)methyllithium to an ester, followed by a sequence consisting of a Wittig reaction, a DIBAL-H reduction and an iodine-mediated cyclization is described.
Abstract A β-hydroxymethyl-γ-butyrolactone, which is a useful intermediate for the synthesis of s... more Abstract A β-hydroxymethyl-γ-butyrolactone, which is a useful intermediate for the synthesis of several natural products with biological activity, was synthesized with good yield and a reduced number of steps from simple commercially available starting materials. Model ...
ABSTRACT In the course of studies on the synthesis and chemistry of betweenanenes we have devised... more ABSTRACT In the course of studies on the synthesis and chemistry of betweenanenes we have devised a short route (Chart I) to symmetrical members of the family (e.g., 4) which we disclose herewith.
The organocerium compound derived from ester (I) readily reacts with symmetrical and unsymmetrica... more The organocerium compound derived from ester (I) readily reacts with symmetrical and unsymmetrical ketones to give γ-butyrolactones as main components and symmetrical diols such as (IV) as by-products.
ABSTRACT A method for the preparation of 3-substituted furans starting with the addition of bis(p... more ABSTRACT A method for the preparation of 3-substituted furans starting with the addition of bis(phenylthio)methyllithium to an ester, followed by a sequence consisting of a Wittig reaction, a DIBAL-H reduction and an iodine-mediated cyclization is described.
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