Disclaimer/Klachtenregeling Meent u dat de digitale beschikbaarstelling van bepaald materiaal inb... more Disclaimer/Klachtenregeling Meent u dat de digitale beschikbaarstelling van bepaald materiaal inbreuk maakt op enig recht dat u toekomt of uw (privacy)belangen schaadt, dan kunt u dit onderbouwd aan de Universiteitsbibliotheek laten weten. Bij een gegronde klacht zal de ...
The age-1(hx546) mutant is long-lived and stress resistant in a daf-16 dependent manner. However,... more The age-1(hx546) mutant is long-lived and stress resistant in a daf-16 dependent manner. However, the molecular nature of the hx546 mutation is unknown and loss of daf-16 function has only a small effect of adult lifespan and stress resistance. We have found that acute ...
Abstract: Haemophilia B, a deficiency in clotting factor IX (FIX), occurs in about 1 in 25.000 ma... more Abstract: Haemophilia B, a deficiency in clotting factor IX (FIX), occurs in about 1 in 25.000 males. Of these patients, approximately 40% are characterized as having 'severe' haemophilia (FIX below 1% of normal). Although the use of plasma-derived or rFIX has extended the ...
Despite surgical intervention the outcome of these patients with esophageal carcinoma is poor and... more Despite surgical intervention the outcome of these patients with esophageal carcinoma is poor and novel treatments are necessary. Dendritic Cells (DC's) are potent antigen presenting cells, which regulate the immune system and are responsible for the activation of both ...
Gastroenterology, Volume 136, Issue 5, Pages A-748, May 2009, Authors:Akueni L. Davelaar; Agniesz... more Gastroenterology, Volume 136, Issue 5, Pages A-748, May 2009, Authors:Akueni L. Davelaar; Agnieszka M. Rygiel; Francesca Milano; Jacques Bergman; Brenda Elzer; Kenneth K. Wang; Paul Fockens; Kausilia K. Krishnadath. ...
BACKGROUND: Barrett's esophagus (BE) is a pre-malignant condition of the distal esophagus th... more BACKGROUND: Barrett's esophagus (BE) is a pre-malignant condition of the distal esophagus that is associated with an increased risk of developing esophageal adenocarcinoma. In order to identify genes specifically involved in the transition of normal squamous esophageal ...
In Barrett's esophagus (BE) the multi-layered stratified squamous epithelium has changed int... more In Barrett's esophagus (BE) the multi-layered stratified squamous epithelium has changed into a single layered intestinal type of columnar mucosa. The biological processes inducing this intestinal type of metaplasia are still poorly understood. The homeobox gene CDX-2, a nuclear ...
Disclaimer/Klachtenregeling Meent u dat de digitale beschikbaarstelling van bepaald materiaal inb... more Disclaimer/Klachtenregeling Meent u dat de digitale beschikbaarstelling van bepaald materiaal inbreuk maakt op enig recht dat u toekomt of uw (privacy)belangen schaadt, dan kunt u dit onderbouwd aan de Universiteitsbibliotheek laten weten. Bij een gegronde klacht zal de ...
The age-1(hx546) mutant is long-lived and stress resistant in a daf-16 dependent manner. However,... more The age-1(hx546) mutant is long-lived and stress resistant in a daf-16 dependent manner. However, the molecular nature of the hx546 mutation is unknown and loss of daf-16 function has only a small effect of adult lifespan and stress resistance. We have found that acute ...
Abstract: Haemophilia B, a deficiency in clotting factor IX (FIX), occurs in about 1 in 25.000 ma... more Abstract: Haemophilia B, a deficiency in clotting factor IX (FIX), occurs in about 1 in 25.000 males. Of these patients, approximately 40% are characterized as having 'severe' haemophilia (FIX below 1% of normal). Although the use of plasma-derived or rFIX has extended the ...
Despite surgical intervention the outcome of these patients with esophageal carcinoma is poor and... more Despite surgical intervention the outcome of these patients with esophageal carcinoma is poor and novel treatments are necessary. Dendritic Cells (DC's) are potent antigen presenting cells, which regulate the immune system and are responsible for the activation of both ...
Gastroenterology, Volume 136, Issue 5, Pages A-748, May 2009, Authors:Akueni L. Davelaar; Agniesz... more Gastroenterology, Volume 136, Issue 5, Pages A-748, May 2009, Authors:Akueni L. Davelaar; Agnieszka M. Rygiel; Francesca Milano; Jacques Bergman; Brenda Elzer; Kenneth K. Wang; Paul Fockens; Kausilia K. Krishnadath. ...
BACKGROUND: Barrett's esophagus (BE) is a pre-malignant condition of the distal esophagus th... more BACKGROUND: Barrett's esophagus (BE) is a pre-malignant condition of the distal esophagus that is associated with an increased risk of developing esophageal adenocarcinoma. In order to identify genes specifically involved in the transition of normal squamous esophageal ...
In Barrett's esophagus (BE) the multi-layered stratified squamous epithelium has changed int... more In Barrett's esophagus (BE) the multi-layered stratified squamous epithelium has changed into a single layered intestinal type of columnar mucosa. The biological processes inducing this intestinal type of metaplasia are still poorly understood. The homeobox gene CDX-2, a nuclear ...
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