FAA (disambiguation)

FAA commonly refers to the Federal Aviation Administration, a United States government agency.

FAA may also refer to:

2-Acetylaminofluorene

2-Acetylaminofluorene (AAF, 2-AAF) is a carcinogenic and mutagenic derivative of fluorene. It is used as a biochemical tool in the study of carcinogenesis. It induces tumors in a number of species in the liver, bladder and kidney. The metabolism of this compound in the body by means of biotransformation reactions is the key to its carcinogenicity. 2-AAF is a substrate for cytochrome P-450 (CYP) enzyme, which is a part of a super family found in almost all organisms. This reaction results in the formation of N-hydroxy-2-acetylaminofluorene which is a proximal carcinogen and is more potent than the parent molecule. The N-hydroxy metabolite undergoes several enzymatic and non-enzymatic rearrangements. It can be O-acetylated by cytosolic N-acetyltransferase enzyme to yield N-acetyl-N-acetoxyaminofluorene. This intermediate can spontaneously rearrange to form the arylamidonium ion and a carbonium ion which can interact directly with DNA to produce DNA adducts. In addition to esterification by acetylation, the N-hydroxy derivative can be O-sulfated by cytosolic sulfur transferase enzyme giving rise to the N-acetyl-N-sulfoxy product.

Federal Aviation Administration

The Federal Aviation Administration (FAA) is the national aviation authority of the United States. As an agency of the United States Department of Transportation, it has authority to regulate and oversee all aspects of American civil aviation. The Federal Aviation Act of 1958 created the organization under the name Federal Aviation Agency. The agency adopted its current name in 1966 when it became a part of the U.S. Department of Transportation.

Major functions

The FAA's roles include: