Determining Mitral Stenosis Through Radial Arterial Pulse: A Computational Understanding

Mitral Stenosis (MS) is an abnormal condition of the heart mitral valve in which the valve orifice area is reduced leading to many complications in heart function. Noninvasive and less expensive procedures for diagnosis are not currently available. The aim of this work was to explore the use of the radial artery pulse (RAP) to diagnose MS. This paper analyzed the effect of the development and growth of MS on possible radial artery noninvasive assessment parameters. For this, MS was introduced to ex vivo by varying the orifice area to either 1, 2, 3, 4 or 5[Formula: see text]cm2 in a hybrid cardiopulmonary electrical analogous model based on clinically obtained healthy controls with an orifice area of 6[Formula: see text]cm2. Results showed that a mitral valve area less than 2[Formula: see text]cm2 significantly influenced the pulse magnitude and time parameters. A strong correlation was observed in pulse height (PH), mean pulse height (MPH), and time occurrence of the dichotic notch...