One of the information technology applications in the cancer care process is positive identification of patients; several studies show that misidentification in cancer care may cause many problems such as lots of medical errors due to wrong person. Improvement in cancer care processes for positive patient identification through information technology is necessary to reduce mortality and morbidity rate; because errors due to misidentification decrease patient safety. For this reason patient identity information should be clear and explicit. Applying new technologies and standardized methods of patient positive identification can prevent these errors; and enhance the quality of cancer care process. In this literature review, search was conducted with keywords including cancer, positive identification, patient misidentification, information technology, Wireless networks, Barcodes, RFID, and Biometric in Science Direct, Google Scholar, and PubMed databases since 1989 until now. This stu...

Background With the advent of "omics" (e.g. genomics, transcriptomics, proteomics and phenomics), studies can produce enormous amounts of data. Managing this diverse data and integrating with other biological data are major challenges for the bioinformatics community. Comprehensive new tools are needed to store, integrate and analyze the data efficiently. Description The PhenoGen Informatics website http://phenogen.uchsc.edu is a comprehensive toolbox for storing, analyzing and integrating microarray data and related genotype and phenotype data. The site is particularly suited for combining QTL and microarray data to search for "candidate" genes contributing to complex traits. In addition, the site allows, if desired by the investigators, sharing of the data. Investigators can conduct "in-silico" microarray experiments using their own and/or "shared" data. Conclusion The PhenoGen website provides access to tools that can be used for high-throu...

OBJECTIVES An increasing number of Americans are turning to kratom for self-management of various pain, anxiety, and mood states and as an opioid substitute. Addiction to this unique botanical develops and carries a high relapse risk and, to date, there are no guidelines on how to maintain long-term abstinence. The aim of this article is to compile all available information on management of "kratom use disorder" (KUD)-as coined here-from the literature, with evidence from the clinical practice of expert addictionologists in an attempt to develop a standard of care consensus. METHODS A systematic literature search was conducted to capture all relevant cases pertaining to maintenance treatment for KUD. Results were supplemented with case reports and scientific posters gleaned from reliable online sources and conference proceedings. Additionally, a survey of members of the American Society of Addiction Medicine (ASAM) was administered to assess the practice patterns of expert...

Background: Transposed elements (TEs) are known to affect transcriptomes, because either new exons are generated from intronic transposed elements (this is called exonization), or the element inserts into the exon, leading to a new transcript. Several examples in the literature show that isoforms generated by an exonization are specific to a certain tissue (for example the heart muscle) or inflict

Electronic Health Records are a digital version of paper-based records. Studying previous treatment, care and medications is important for making diagnosis for the current situation. The aim of this paper relates to the use of EHR as a means of communication between patient and health care provider with a focus on how EHRs communicates health information for unconscious patient to physicians. As accessing records requires credentials of patient and if the patient is not in a condition to enter his credentials, this leads to the scope of dynamic access control. Dynamic access control is provided by dividing EHRs into different levels. The basis for these levels is physician’s specialization and patient’s health status. This framework is implemented with the help of a WAMP server using PHP and MySQL.

Motivation: Normalizing diverse representations of sequence variants is critical to the elucidation of the genetic basis of disease and biological function. NCBI has long wrestled with integrating data from multiple submitters to build databases such as dbSNP and ClinVar. Inconsistent representation of variants among variant callers, local databases, and tools results in discrepancies and duplications that complicate analysis. Current tools are not robust enough to manage variants in different formats and different reference sequence coordinates. Results: The SPDI (pronounced "speedy") data model defines variants as a sequence of 4 operations: start at the boundary before the first position in the sequence S, advance P positions, delete D positions, then insert the sequence in the string I, giving the data model its name, SPDI. The SPDI model can thus be applied to both nucleotide and protein variants, but the services discussed here are limited to nucleotide. Current serv...