General surgery
Letter to the Editor
Concomitant laparoscopic sleeve gastrectomy and
laparoscopic cholecystectomy in a morbidly obese
patient with situs inversus totalis
Volkan Yigit1, Kenan Binnetoglu2, Mürşit Dincer3
1
Department of General Surgery, Memorial Hospital, Diyarbakir, Turkey
Department of General Surgery, Kafkas University Hospital, Kars, Turkey
3
Department of General Surgery, Firat University Hospital, Elazig, Turkey
2
Submitted: 13 November 2020
Accepted: 7 February 2020
Arch Med Sci Civil Dis 2021; 6: e8–e11
DOI: https://doi.org/10.5114/amscd.2021.105387
Copyright 2021 Termedia & Banach
Situs inversus totalis (SIT) is a rare congenital condition in which the
major visceral organs within the thorax and abdomen are reversed from
their normal positions. Its incidence is 1 in 10 000–50 000 of the population [1]. It presents difficulties in laparoscopic surgery, because of the
mirror-image anatomy. Laparoscopic surgical treatments of some conditions in patients with situs inversus totalis such as acute appendicitis,
cholelithiasis, and morbid obesity have been previously reported [2–4].
Herein we report a case of situs inversus totalis treated with concomitant laparoscopic sleeve gastrectomy (LSG) and laparoscopic cholecystectomy (LC).
A 28-year-old woman who had a body mass index 46.9 kg/m2 was
electively admitted to the department of general surgery for LSG. She
had a history of myringotomy for otitis media in childhood. She had situs inversus totalis diagnosis at that time. Physical examination revealed
the apex beat on the right side. Chest X-ray from the posteroanterior
view demonstrated dextrocardia (Figure 1). Preoperative abdominal ultrasonography also confirmed SIT and revealed cholelithiasis. Laboratory
profiles were normal. It was decided to perform concomitant LSG and LC.
The patient was positioned in the reverse Trendelenburg position
with two video monitors at the shoulder on both sides of the patient
after general anesthesia. The surgeon stood between the patient’s legs
to provide the most ergonomically advantageous position for access to
both upper quadrants of the abdominal cavity. A 10-mm camera port
was inserted using a bladeless optical trocar 2 cm above the umbilicus.
Pneumoperitoneum with CO2 was established with a pressure of 12 mm
Hg. A thirty degree viewing laparoscope was introduced through this
port. The laparoscope confirmed situs inversus totalis (Figure 2). Two 12mm trocars were inserted 6 cm below the subcostal margin in the right
and left upper quadrants along the midclavicular line. A 5-mm trocar
was inserted in the right upper quadrant subcostal area along the anterior axillary line. Another 5-mm trocar was inserted in the subxiphoid
area for the Nathanson liver retractor (Figure 3). The gastrocolic ligament
was dissected to the stomach to 4 cm from the pylorus. The curvature
major was dissected to the angle of His with an electrothermal bipolar
vessel sealing device (Ligasure, Covidien IIc, MA, USA). Traction of the
stomach was carried out by the surgeon’s right hand, and vessel sealing
was carried out by the left hand. A 39-French orogastric tube passed
Corresponding author:
Mürşit Dincer
Department of
General Surgery
Firat University Hospital
Elazig, Turkey
Phone: +905446422820
E-mail: drmursitdincer@
gmail.com
Concomitant laparoscopic sleeve gastrectomy and laparoscopic cholecystectomy in a morbidly obese patient with situs inversus totalis
Figure 2. Laparoscopic exploration
Figure 1. Chest X-ray confirmed dextrocardia
into the stomach for remnant gastric calibration.
The stomach was divided parallel to the orogastric
tube along the curvature minor of the stomach
using an Echelon stapler (Ethicon, Cincinnati, OH,
USA). After a leakage test using methylene blue,
fibrin sealant (Tisseel, Baxter, Glendale, CA, USA)
was applied onto the staple line of the remaining stomach. This stage of the operation lasted
48 min, and it was not more difficult than in patients with normally sited intra-abdominal organs.
Then, the Nathanson liver retractor was taken out
from abdominal cavity and a 5-mm trocar was
re-placed in the subxiphoid area. A window was
created on the falciform ligament. Upward traction of the gallbladder fundus was carried out by
a grasper inserted into the left upper quadrant via
this window (Figure 4). The surgeon used his right
hand to retract the neck of the gallbladder and
Video monitor
Figure 3. Insertion of the trocars
Arch Med Sci Civil Dis 2021
Video monitor
used his left hand to dissect Calot’s triangle. The
dissection of Calot’s triangle was easily carried
out. The cystic duct and artery were identified.
There were no structural abnormalities in these
structures. Both of them were clipped and then divided. After division of all peritoneal reflections on
either side, the gallbladder was retrogradely separated from the liver bed using hook-electrocautery
and Ligasure. This part of the dissection was more
difficult than the dissection of Calot’s triangle for
the surgeon, because the pendulous falciform ligament entering the field of view made it difficult
to dissect the medial peritoneal reflection of the
gallbladder (Figure 5). However, LC was completed
within 27 min without any complications. A drain
was placed in contact with the staple line of the
remaining stomach. The muscles and aponeurosis
of the port sites 12 mm were closed by a suture
passer device. Total time was 86 min.
The postoperative period was uneventful.
A water-soluble upper gastrointestinal contrast
study was performed to detect leakage on the
second postoperative day. There was no leakage
and the patient was allowed a liquid diet. She
was discharged on the fifth day. No complications
have emerged after a 3-month follow-up period.
Weight loss was 27 kg (48% of excess weight).
Figure 4. Laparoscopic cholecystectomy
e9
Volkan Yigit, Kenan Binnetoglu, Mürşit Dincer
trocar for LC. Dissection of the medial peritoneal reflection of the gallbladder was more difficult
than dissection of Calot’s triangle. The only factor
that complicated the dissection of the gallbladder
was the pendulous falciform ligament entering
the field of view.
In conclusion, concomitant LSG and LC procedures in a patient with situs inversus totalis are
more difficult than standard procedures. However,
they can be performed safely without the need for
extra trocar insertion.
Conflict of interest
Figure 5. Dissection of the medial peritoneal reflection of gallbladder
The authors declare no conflict of interest.
References
Situs inversus totalis is a very rare autosomal
recessive entity [5]. It can be easily diagnosed after chest X-ray, abdominal sonography or computed tomography. For the present case, the pre-operative diagnosis of situs inversus totalis was made
by chest X-ray and abdominal ultrasound. Some
abnormalities such as cardiovascular or respiratory may be associated with situs inversus totalis
[4], but our patient has no other abnormalities.
Situs inversus totalis is not a contraindication to
laparoscopic surgery. However, it can present difficulties in laparoscopic surgery, because of the mirror-image anatomy. Right handed surgeons may
have to use their left hand for dissection. However,
this technical difficulty does not make it impossible to complete the operation laparoscopically.
Laparoscopic cholecystectomy is the gold standard for treating symptomatic cholelithiasis [6].
Five additional LC procedure in patients with situs
inversus have been reported since the review of
the literature by Salama et al., who reviewed the
first 50 cases in the literature [3, 7–11]. The general consensus is that the LC will be longer than
in a patient with a normally located gallbladder;
the need to redirect the visual-motor skills of the
surgeon and the cameraman to the left upper
quadrant along with the difficulty in skeletonizing
Calot’s triangle is responsible for the longest portion of the extra-operative time [12]. The reported
cases of concomitant laparoscopic procedures for
different organs in patients with SIT are extremely
rare [5, 13–15].
Laparoscopic sleeve gastrectomy accounts for
approximately 30% of bariatric procedures performed worldwide; and its coexistence with partial situs inversus is one in a million [16]. There
are only five reported cases of LSG in a patient
with situs inversus in the literature [4, 16–18]. To
date, there is no report about a patient with SIT
who underwent concomitant LSG and LC. In the
present case, we had no need to insert any extra
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