Mental Machinery and Active Powers from Hartley to Ward

Livy’s narrative of the 169 b.c.e. invasion of Macedonia led by the consul Q. Marcius Philippus is of particular interest because his principal source here, Polybius, accompanied the Roman army (Polyb. 28.13.1–6). However, the text of Book 44 is based on a single lacunose, jumbled, and corrupt manuscript dating to the fifth century C.E. and known as the Codex Vindobonensis or V. In this article we address textual problems in the narrative, both those represented by cruces in Briscoe’s Teubner edition of Books 41–45 and others where currently accepted emendations seem to us capable of improvement.

Cet article étudie les raisons philosophiques qui amènent Galeotto Marzio da Narni à promouvoir l'arabe comme langue scientifique, héritière des savoirs grecs et romains, dans une complémentarité des cultures. La diversité des langues et des croyances s'expliquerait en effet par la conjonction de phénomènes astraux, de particularités climatiques et de circonstances historiques. Ce relativisme l'amène à défendre des thèses radicales sur le salut des païens, des hérétiques et des infidèles.

Background: Substandard and falsified (SF) medical products are removed from circulation through a process called 'product recall' by medicines regulatory agencies. In Zambia, the Zambia Medicines Regulatory Authority (ZAMRA) is responsible for recalling SF medical products from the Zambian market through passive and active surveillance methods. This study aimed to describe the prevalence of recalls of SF medical products and to analyse the frequently recalled therapeutic categories, dosage forms, categories of defects that led to the recalls and their sources with respect to the country of the marketing authorisation holder (MAH) or manufacturer. Methods: We conducted a descriptive cross-sectional review of the product recalls issued by ZAMRA between January 2018 and December 2021. A search for all medical product alerts and recalls issued by ZAMRA was carried out by reviewing the internal post-marketing surveillance database kept at ZAMRA headquarters. Data were extracted using a structured Excel database and analysed using Microsoft Excel. Results: A total of 119 alerts were received during the review period, of which 83 (69.7%) were product recalls. Oral solid dosage forms were the most recalled dosage form (53%). Furthermore, the number of recalls increased in 2020 (44.6%) and 2021 (22.9%), with the majority (20.5%) of the recalled products being substandard products classified as antiseptics and disinfectants and were attributed to the high demand during the COVID-19 pandemic. Manufacturing laboratory control issues were the reason for product recall in almost half (47.4%) of the cases. Most of the products recalled originated from India (38.6%), followed by Zambia (25.3%). Only one suspected falsified product was recalled between 2018 and 2021. A total of 66 recalls of the 83 products were initiated by ZAMRA, with only 17 voluntarily by foreign MAHs. No product recall was initiated by the local representatives of foreign manufacturers or MAH. Conclusion: The majority of the pharmaceutical product recalls in Zambia were substandard products. Manufacturing laboratory control issues lead to most recalls and require investigation of the root causes, preventive action, and strict compliance with the good manufacturing practices guidelines by manufacturers.

This is a review paper of some writings or literatures which presents the edible mushroom cultivation and processing including types, production and its scenario. Mushroom is a fungus considered to be edible due to its high nutrition facts. It is a great source of vitamin D, some minerals and protein. In addition, due to short or quick growing, good prices and health benefits, it is popular amongst farmers and new entrepreneurs. Their spawns are produced carefully in healthy conditions and sown on a well prepared compost bed containing required nutrition for spawn. Harvesting starts 50 to 55 days after sowing and mushrooms are twisted in opposite directions for harvest. Their fleshy nature leads to deterioration if not consumed within some hours or refrigerated or not utilized for canning, pickling, drying etc. which are post harvesting processes.

Un giorno a Musarna, piccolo centro etrusco dell'Etruria meridionale interna che risale all'età ellenistica, sviluppatosi sotto l'influenza politica e culturale di Tarquinia. Rivivono necropoli, sistema difensivo e vita quotidiana nel centro abitato, caratterizzato da isolati divisi da strade ad angolo retto, piazza per la vita pubblica e impianto termale. Nel calidarium venne alla luce una iscrizione in lingua etrusca, preziosa testimonianza del persistere della lingua madre anche dopo la romanizzazione.

Gender issues within the police organisation, personnel structure and police culture have only recently become the subject of detaild academic research. There are still relatively few culture studies dealing with cross-analysis of the position, role, perspective and barriers to inegration of women police officers. Available studies mostly compare the experiences of Great Britain and the United States of America. This paper is of analytical nature. Its hypothetical basis starts from conceptual determinants of the notion of police culture and the objective and subjective barriers to the integration of women into the police based on that culture. The subject of the research is the experience (barriers, opportunities and challenges) of the women employed in the police during the process of their integration and acceptance in a male dominated work environment in different parts of the world: America, Japan, Canada, India, Ukraine. The research findings confirmed that the woman employed in the police, primarily the uniformed police, are exposed to many stressful situations, challenges of the specific police tasks and to various forms of discrimination. The following are recognized as the sources of discrimination: hostile work environment with a steady bases of police culture, built up for decades, and various forms of harassment. The analysed results are presented as illustrative trends, not as a definitive findings.

This paper introduces a next-generation device for crop yield prediction that utilizes IoT and machine learning technologies. The device was implemented and tested, and it was found to have a high level of accuracy in predicting crop yields. It is a combination of three different machine learning models: Artificial Neural Network (ANN), Fuzzy Logic, and Support Vector Machine (SVM). The IoT sensors in the device gather data on various environmental and soil conditions such as temperature, humidity, and soil moisture, which is then fed into the machine learning models. The ANN is used to analyze the sensor data and extract features, the Fuzzy Logic model is used to handle uncertainty in the data and make predictions, and the SVM model is used for classification. The device was tested on various crops and it was observed that the accuracy of the predictions was good and the results were comparable to other state-of-the-art techniques. This technology has the potential to revolutionize the way farmers manage their crops and improve crop yields. It can also be used for crop forecasting, crop monitoring, and precision agriculture. By providing accurate and real-time information about crop yields, this device could help farmers make better decisions about their crops and increase their overall productivity and profitability.

Oligonucleotide aptamers seem to be promising delivery vehicles addressing boron compounds to tumour cells for boron neutron capture therapy (BNCT). Here, we report the first example of using 2'-F-RNA aptamer specific to human glioblastoma cells as a delivery agent for boron clusters, which provides cell internalisation sufficient for the BNCT model.

Sepsis is one of the challenges for the doctors who treat critically ill patients. Delay in diagnosis and late administration of antibiotics have been shown to increase the mortality in this cohort. Objective: This study was done to evaluate whether microalbuminuria can be used as a marker of sepsis and also to compare with the levels of C-reactive protein (CRP a traditional marker) of patients admitted in ICU. The study was carried out in the department of Biochemistry, B.J. Medical College and Sassoon general hospitals, Pune. Method: 50 adult patients with ICU stay of more than 24 hrs were included in the study. 50 healthy and age, sex matched controls were also included in the study. Patients with pregnancy, menstruation, anuria, macroscopic hematuria, urinary tract infection, any renal disorder and marked proteinuria were excluded from the study. Blood and spot urine samples were collected on admission and after 24 hrs. Urinary microalbumin was measured in terms of albumin creat...

Nowadays, decision-making is highly challenging in the alignment of decisions to support the success of plant performance and business goals. In this sense, enterprises comprise several functions which interact with each other, such as production, marketing, sales, human resources, logistics, safety and environment. Therefore, it is important to provide systems capable of representing and considering the different elements involved in the enterprise decision making task. In this area, knowledge management technologies have proved to be highly promising for improving information sharing and communication, enhancing the enterprise operation. The industrial waste management stands for an end-of-pipe problem involving gas, liquid or solid effluents which contain contaminants originated from industrial activities. Waste streams must meet discharge constraints imposed by environmental regulations before being disposed of in the environment. Thus, waste treatment plants comprise several te...

Clear cell renal cell carcinoma (ccRCC) is a hypervascular tumor that is characterized by bi-allelic inactivation of the VHL tumor suppressor gene and mTOR signalling pathway hyperactivation. The pro-angiogenic factor PDGFB, a transcriptional target of super enhancer-driven KLF6, can activate the mTORC1 signalling pathway in ccRCC. However, the detailed mechanisms of PDGFB-mediated mTORC1 activation in ccRCC have remained elusive. Here, we investigated whether ccRCC cells are able to secrete PDGFB into the extracellular milieu and stimulate mTORC1 signalling activity. We found that ccRCC cells secreted PDGFB extracellularly, and by utilizing KLF6- and PDGFB-engineered ccRCC cells, we showed that the level of PDGFB secretion was positively correlated with the expression of intracellular KLF6 and PDGFB. Moreover, the reintroduction of either KLF6 or PDGFB was able to sustain mTORC1 signalling activity in KLF6-targeted ccRCC cells. We further demonstrated that conditioned media of PDGF...

In this study, ZnO-TiO2/ZAH photocatalyst were synthesized by impregnation method with active metal sites of zink from Zn(SO4).7H2O into TiO2/ZAH. The physicochemical propreties of the material were determined by Xray diffraction (XRD), X-ray fluorescense (XRF), Gas sorption analyzer (GSA), and UV-Vis diffuse reflectance spectrophotometry (UV-Vis DRS). The photocatalytic activity of the ZnO-TiO2/ZAH was evaluated by photocatalytic degradation of textile industry wastewater under UV-irradiation. Result of characterization show that the ZnO particles were succesfully distributed in TiO2/ZAH. COD reduction in textile industry wastewater at 93.5% with optimum contact time of 3.0144 minutes and deactivation type is real.