Journal of Evaluation in Clinical Practice ISSN 1356-1294
Preliminary reliability of an observer rating scale for
assessing medication adherence on psychiatric wards
Mitchell K. Byrne MAppPsych,1 Frank P. Deane PhD,2 Aimee Willis BPsych,3 Barbara Hawkins PhD4 and
Rebecca Quinn PhD5
1
Lecturer, Clinical Psychology, 2Director, Illawarra Institute for Mental Health, 3Research Officer, Illawarra Institute for Mental Health, Illawarra
Institute for Mental Health and School of Psychology, University of Wollongong, Wollongong, New South Wales, Australia
4
Director of Research, 5Director, Center for Adult Services, Western State Hospital, 9601 Steilacoom Boulevard SW, Lakewood, WA, USA
Keywords
inpatient, measure, medication adherence,
psychiatric, rating
Correspondence
Mitchell K. Byrne
School of Psychology
University of Wollongong
Wollongong
NSW 2522
Australia
E-mail: mbyrne@uow.edu.au
Accepted for publication: 8 February 2008
doi:10.1111/j.1365-2753.2008.00989.x
Abstract
Objectives Medication non-adherence is a major contributor to poor outcomes following
discharge from psychiatric hospitals. It is therefore imperative that staff are able to accurately assess the extent to which patients have engaged with treatment. This study presents
data on a new observer rating instrument of patient medication adherence.
Methods Staff participating in a medication adherence training programme (‘Medication
Alliance’) were given a brief overview of the Observer Rating of Medication Taking
(ORMT) scale. Participants then watched six video vignettes of patient adherence behaviour and provided a rating on their scale for each vignette. Participant ratings were then
compared with ‘expert’ ratings.
Results Percentage agreement between ‘experts’ and participants ranged from a low of
68% through to 98% agreement. Only one vignette was rated significantly differently
[Mdiff = 0.33, t(49) = 2.08, P = 0.007], with 32% of people falling outside the expert rating
range (all of those ratings being higher). This difference was attributed to between group
differences, [F(2,47) = 3.49, P < 0.05] and post hoc assessment suggested that the differences between expert and trainee ratings for the vignette may be explained by trainee
characteristics, as distinct from inherent characteristics of the rating scale.
Conclusion The ORMT can help mental health professionals identify particular nonadherent behaviours thus facilitating identification and treatment of likely non-adherence
before discharge. The scale appears to be accessible to a variety of professions with a range
of experience and requires minimum training in order to be used reliably.
Introduction
Individuals taking prescribed medication have been found to demonstrate significant levels of non-adherence [1], with this being
especially common in psychiatric patients [2]. Patients may fail to
take their medication; they may discontinue their treatment early;
or they may continue to take their medication, but deviate from the
prescription [3]. These problems are significant throughout the
health sector and have led to a need for accurate and practical tools
to screen adherence [4].
There are a wide range of methods which have been used to
assess medication adherence, including self-reports, prescription
monitoring, pill counts, biological markers and electronic monitoring [5]. However, most methods are open to manipulation,
distortion, and misinterpretation [5] and no single method has been
found to have successful application to all forms of research in the
area [3]. Furthermore, even when the measurement of adherence
246
matches the research question, cut off points for adherence versus
non-adherence are often chosen arbitrarily [3].
Judging whether or not any particular method is valid in measuring medication adherence is further complicated by the inherent
limitations of each method. For example, testing urine and blood
drug levels cannot quantify the manner or pattern of compliance
and do not give information about extended intervals [6]. Furthermore, individual variation in metabolism can often distort biological markers or levels [3]. Self-report is arguably the simplest
method to measure compliance and some authors have found
self-report to be quite accurate, with 75% of patients identifying
themselves as compliant or non compliant consistently with their
pill count [7]. While some research has identified self-report as
having high sensitivity for repeat non-adherence [4], self-report
has more generally been found to be susceptible to unreliable
responding, particularly towards patients over estimating compliance [3]. The skill of the interviewer and the structure of
© 2009 The Authors. Journal compilation © 2009 Blackwell Publishing Ltd, Journal of Evaluation in Clinical Practice 15 (2009) 246–251
M.K. Byrne et al.
questions asked of the individual can influence the accuracy and
validity of this method [3].
Pill counts calculate the number of dosage units taken by the
patient, but this has also been seen as untrustworthy [6]. There is
no guarantee that patients have actually consumed the medication,
and it also does not indicate the pattern of adherence [3]. Electronic monitoring records the time and date on each occasion a
bottle of medication is opened. However, the opening of a bottle
does not necessarily mean that the medication has actually been
taken and as such, this method is likely to overestimate adherence
[5].
The most significant issue with the range of methods available
to measure medication adherence is that they seem to lack validity
in that there is inconsistency between measures. The significant
discrepancies between measures suggest the need for further
research to help improve tools and strategies to assess medication
adherence. More importantly, tools need to be open to reliability
assessments based on observable behaviour. One option for
achieving such an outcome is through the use of observer rating
scales to measure adherence behaviour.
There is one known example of an observer rating scale for
assessing medication adherence. As part of a study by Kemp,
Hayward, Applewhaite, Everitt and David [8] to assess the effects
of Compliance Therapy in promoting medication adherence in
psychiatric patients, a 7-point observer rating scale was used. This
scale scored ‘complete refusal’ as ‘1’ and ‘active participation’ as
‘7’. Compliance behaviour was described allowing patient behaviour to be categorized. Initial ratings of compliance were made
by the patients’ primary nurses, then 3 months later a composite
measure was obtained using the same scale, but from a variety of
sources (including relatives, psychiatrists and general practitioners). Evaluations at 6 months were completed by an independent
rater. Concurrent validity of the scale was demonstrated through
strong correlations between observer assessments and selfreport measures. Unfortunately, these ‘observations’ were global
summary ratings and the criteria were not well specified, nor was
reliability of the measure or reliability between raters reported.
The current study describes the development of an observational
scale of medication adherence behaviour in inpatient settings and
provides a preliminary assessment of its interrater reliability.
Previous studies and measures have been found to focus on
medication adherence in outpatients. However, a frequent reason
for relapse and re-hospitalization is non-adherence with medication [9]. As a result a common goal of inpatient treatment is
re-establishment of medication taking and improved adherence
behaviour of patients. It is important to acknowledge that psychiatric hospitals need to not only focus on the stabilization of
patients, but also self-management of their disorder so that upon
their discharge they are capable of managing their illness in the
community. Unfortunately, there are no behaviourally defined
observer rating scales to help systematically assess adherence in
inpatient settings.
As part of scale development for the current study, informal
consultations were made with senior clinical staff and observations
were made on the ward of medication dispensing in inpatients
settings (Washington State, USA and also New South Wales State,
Australia). The most common form of medication dispensing was
for a ‘medication call’ at specified times of the day (typically
morning, afternoon and evening) when patients would come to a
© 2009 The Authors. Journal compilation © 2009 Blackwell Publishing Ltd
Observer rating scale of medication adherence
nurses station to receive their medications. The level of prompting
at this time varied somewhat but generally involved a ‘call’ for
patients in the day rooms to come to collect their medications.
Typically, individuals would then go to the nurses’ station (and
line up if necessary). Those who did not attend or who were in
their rooms would usually be prompted by a nurse or other ward
staff. By far this was the most common form of medication
dispensing and so we chose to use this as the pivotal event
for observational ratings of medication adherence behaviour.
Although there were other methods of dispensing, these were
relatively infrequent. For example, where staffing allowed, nurses
would go to individual patient’s rooms or a medication cart might
go from room to room. However, often there were insufficient staff
and there were concerns about security of medications and safety
with this method. In addition, some wards allow patients to ‘selfmedicate’, which involves them holding their own medications
and dispensing at the required times. Although such strategies may
be ideal for helping patients increase their personal responsibility
for self-management, in practice, self-medication on wards was
rare, again owing to concerns about security of medications (e.g.
theft, sale) and because most wards did not have the facility for
secure (locked) storage lockers for individual patients.
This study aimed to provide a preliminary assessment of the
reliability and levels of agreement of the medication adherence
observer rating scale among a cross-section of inpatient ward staff.
Methods and materials
Participants
Data were derived from participants in a medication adherence
training programme (‘Medication Alliance’ [10]). In all, 60 participants completed the programme but data on the medication
adherence observer rating scale were only obtained from 50 of
these participants. Given that the medication adherence observer
rating scale data were anonymous, demographic information was
derived from the full sample of 60 participants who completed
other programme evaluation activities and provided background
descriptive data. As a result, this is can only be considered broadly
representative of the 50 participants who provided medication
adherence observer rating scale data for this study.
Participants were mental health staff from the Western State
Psychiatric Hospital in Lakewood, Washington, USA. In all, 58%
were female and 42% male, with a mean age of 47.5 years
(SD = 10.6 years). Most of the participants were nurses [37%],
although a large number were Mental Health Technicians (MHTs
– 29%). MHTs do not have formal tertiary qualifications in health
services but rather are trained ‘on the job’ to support clinical
personnel. The remainder of the participants were institutional
counsellors [8%], social workers [7%], rehabilitation specialists
[7%], psychiatrists [5%], psychologists [3%] and occupational
therapists [3%]. Most had worked for a significant period in their
profession (M = 14.9 years, SD = 10.3 years), with the bulk of
this experience at Western State Hospital (M = 9.3 years,
SD = 7.2 years). The highest educational achievement was undergraduate degree [45%], followed by senior high school [31%] and
finally postgraduate qualifications [24%]. Three quarters of the
participants [77%] stated that they had never received training in
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Observer rating scale of medication adherence
relation to medication adherence prior to their participation in
Medication Alliance training.
Measures
The Observer Rating of Medication Taking (ORMT) (see Appendix) ranges from 1 (‘fully non-adherent’) through to 7 (‘fully
adherent’). A copy of the ORMT is appended to this article. Each
of the 7 points has behavioural descriptors. These are supplemented with descriptors for rating between each of the 7 points
(e.g. ‘between 3 and 4’). There is a broad orienting guide with
ratings from 7 to 4 that generally indicate adherence with varying
degrees of prompting, and from 4 to 1 which indicate nonadherence with varying degrees of resistance. On the ward, each
patient’s medication taking behaviour would be rated once per day
for one week using the ORMT. If the patient has multiple doses
across each day, then one rating is taken sequentially for each
medication period, rotating between periods across the week. An
average score for the individual patient across the week can then
obtained to monitor progress over time.
Materials
The study used six brief video vignettes that provided examples of
different responses to medication taking on a ward as stimulus
materials for participants to rate adherence levels. Transcripts for
the vignettes are provided below along with the length of each
video. The vignettes were designed to assess the range of ratings
possible on the ORMT, but also included vignettes that were likely
to be close to each other in terms of adherence ratings. This would
allow a test of the range, but also the capacity to assess relatively
subtle differences in behaviour. The videos were rated independently by the first two authors, who have extensive experience in
medication adherence training (e.g. ref. [10]). In addition, a third
expert who was an experienced clinical psychologist also provided
an independent rating. All three independent expert ratings (ER)
had the scores in the same rank order and all except one (Vignette
B) were within one rating point of each other. The average of these
ratings, rounded to the nearest 0.5 was taken as the ‘expert’ ratings
for each of the vignettes. The final ER for each vignette were:
A = 2.0, B = 4.5, C = 3.0, D = 6.0, E = 6.5 and F = 7.0.
Vignette A (32 seconds)
Two staff approach a patient sitting in the day room reading a
paper.
Staff: ‘John, John listen mate we’ve been talking to you for about,
what the last twenty minutes or something like that about taking
your medication, ok? Listen if you are not going to take it voluntarily we are going to have to give you an injection.’
Patient tosses paper to the floor as he rapidly jumps up out of seat
with a broad stance, legs apart, hands on hips and very (overly
close) to the smaller of the two staff and glares at her. The staff
takes a step backward and states calmly but firmly . . .
Staff: ‘Now John what you need to do now is just sit down and
calm down.’
Patient: Turns rapidly. Roughly knocks a chair out of the way
knocking it over and says, ‘I’m going to my room.’ (patient exits
to his room)
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M.K. Byrne et al.
Vignette B (20 seconds)
Patient is listening to the radio in the day room with headphones
on.
Staff: ‘Mary, Mary, I’ve called you a couple of times to come and
get your medications. Did you hear me the first time?’
Patient: (looks up distracted, removes headset and states in neutral
tone) ‘Yes’
Staff: (in friendly manner) ‘Alright well why don’t we go through
now and get it?’
Patient: (slowly rises, places headset onto the table and walks
towards the nurses station to get her meds without saying anything).
Vignette C (22 seconds)
Patient sitting in the day room next to another patient.
Patient 1: ‘How ya going?’
Patient 2: ‘Oh, not too bad. How are you?’
Patient 1: ‘Good, good.’
Nursing staff approaches patient. As the nurse approaches the
patient the target patient says to the other patient.
Patient: (cynical and hostile directed to the other patient) ‘Here
comes the damned pusher man again, they’re worse than drug
dealers.
Staff: (firmly) ‘Come on John it’s time to take your medication.
Come through with me.’
Patient: (stands rapidly and says in hostile resentful manner) ‘So if
I don’t take my medication you won’t let me out for a damned
cigarette!’
Staff: ‘Come on man come through, this way.’
Vignette D (11 seconds)
Nurse approaches a patient on the ward who is reading a magazine.
Staff: ‘Hey Paul, you need to get your medication now OK?’
Patient stops reading magazine immediately and gets up from the
couch, placing the magazine onto the table and goes to get the
medication.
Vignette E (48 seconds)
Clock on the nursing station wall shows 18.30 hours.
Patient approaches the nursing station unprompted.
Patient: ‘Is it medication time yet?’
Staff: ‘Ah, no. Dorothy not, not quite yet. Ahem you’ve got about
another half hour to go. Yeah, so how about you come back in
about half an hour – yeah?’
Patient: ‘Oh. OK. Hey, are we going to have another one of those
Recovery groups again?’
Staff: ‘Ahem we might be doing that. I’ll talk to you about that
later, OK Dorothy?’
Patient: ‘OK.’
Staff: ‘see you in half an hour.’
Patient: ‘OK.’
Fades out, then fades in to show Clock at 19.00 hours.
Nurse: ‘Hi Dorothy. By the way do you know what you’re taking?’
Patient: ‘Yep.’
Nurse: ‘What meds you’re taking?’
© 2009 The Authors. Journal compilation © 2009 Blackwell Publishing Ltd
Observer rating scale of medication adherence
M.K. Byrne et al.
Table 1 A comparison of expert and participant ratings of medication adherence in the
vignettes
Trainee ratings
Comparisons of trainee against expert rating (ER)
Vignette
ER
M
SD
% within 0.5 of ER
% below ER
% above ER
A
B
C
D
E
F
2.0
4.5
3.0
6.0
6.5
7.0
1.92
4.83*
3.20
5.99
6.68
6.96
0.48
0.82
0.75
0.62
0.57
0.16
80
68
72
90
96
98
28
36
22
16
8
8
12
44
34
28
60
0
*P < 0.05, 2-tailed, Trainee mean ratings were significantly different from the Expert rating.
Patient: ‘Yes, two white ones.’
Nurse: ‘You’re right. I wonder, do you know what they are for?’
Patient: ‘Yep.’ (picks up cup with medication, turns and walks
away from the nursing station)
Vignette F (15 seconds)
Patient approaches the nursing station, taps on the door frame and
asks staff unprompted . . .
Patient: ‘Is it medication time yet?
Staff: (who is reading some reports) ‘Oh Hi Dot, yes it is. Hang on
one second.’ (get medications from cupboard). ‘So you know your
medication recently changed?’
Patient: ‘Yes.’
Procedure
As part of a training session on medication adherence (‘Medication Alliance’), participants were trained in the use of the ORMT.
All participants were informed that participation was voluntary
and that their responses would be anonymous. They were told not
to put their names or any other identifying information on their
forms. Data were derived from three different training groups.
Participants were first given a brief overview of the ORMT
measure. This involved the trainer reading the descriptions for the
anchors of the 7, 1 and 4 ratings (in that order). Participants then
reviewed each of the other points to become familiar with the
scale. This whole process took approximately 10 minutes. They
then watched the six video vignettes and provided a rating on their
scale for each. They also had access to the scripts to refer to if
needed. After each video, participants were given about 2 minutes
to make their rating.
After all the ratings were completed, each of the vignettes was
provided with an agreed ‘class’ ranking on a white board based on
a brief class discussion and a show of hands to indicate the general
consensus score. The ER of each vignette was then revealed and
discussion about what differentiated each of the ratings was provided. The whole session took approximately 30 minutes for each
group. All ratings were returned anonymously to the researchers at
the end of the session.
Results
The mean ratings from the trainees along with the ER can also be
found in Table 1. First, the percentage of trainees who provided
ratings within 0.5 either side of the ER were considered to have a
© 2009 The Authors. Journal compilation © 2009 Blackwell Publishing Ltd
satisfactory level of agreement. Percentages ranged from a low of
68% agreement (Vignette B) through to 98% (Vignette F). The
percentage who overestimated and underestimated based on the
expert value is also provided for descriptive purposes, with these
values not including those who matched the ER. For example, for
Vignette A, 28% rated below the ER and 12% above therefore 60%
matched the ER. Finally, one sample t-tests were conducted using
the ER as the criterion value. Using a 2-tailed test, there was a
significant difference between ER and trainee mean ratings for
Vignette B (Mdiff = 0.33), t(49) = 2.08, P = 0.007), with 32% of
people falling outside the ER range (all of those ratings being
higher).
The proportion of participants whose ratings ranked the
vignettes in the correct order, from least adherent to most adherent
(i.e. A, C, B, D, E, F) was also investigated. It was found that 48%
of participants ranked the Vignettes in the correct order. Owing to
some of the vignettes being quite close in their ER, quite a few
equal rankings resulted, especially for Vignettes E and F where
50% of rankings were equal. As a result, the proportion of those
who correctly ranked the vignettes was calculated treating
vignettes E and F as the same rank. After making this adjustment,
76% of participants were classified as ranking the vignettes in the
correct order.
Finally, in order to explore the possibility that differences in
group characteristics or training might be responsible for some of
the variability in ratings, a one-way anova was conducted for the
three training groups as the Independent variable and each of the
vignette ratings as dependent variables. There were no significant
differences between groups except for ratings on Vignette B,
F(2,47) = 3.49, P < 0.05. Post hoc Least Squares Difference tests
indicated that for this vignette, the mean rating by Group 1
(M = 4.44, SD = 0.56, n = 18) was significantly lower than both
Group 2 (M = 5.04, SD = 0.94, n = 14) and Group 3 (M = 5.06,
SD = 0.85, n = 18) (both P < 0.05). This suggests that the differences between expert and trainee ratings for Vignette B in part be
explained by trainee or training characteristics as distinct from
inherent characteristics of the rating scale. It is notable that the
mean for Group 1 was closer to that of the ER.
Discussion
These results are promising in terms of using this measure to help
mental health professionals identify particular non-adherent
behaviours. It appears that in the majority of cases the trainees
were relatively accurate in their ratings, with the averages being
quite consistent with the ER and a high percentage of trainees
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Observer rating scale of medication adherence
rating within 0.5 either side of the ER. Participants demonstrated
most difficulty when rating vignette B. Analysis of between group
differences among trainees suggested that the relatively low reliability for vignette B may in part be explained by either trainee
characteristics (occupation) or variation in training experience.
Unfortunately, we could not match trainee descriptive characteristics with vignette ratings to test this further.
Vignettes B and C both had relatively low percentages of trainees rating the vignette correctly compared with the ER. It may be
that these vignettes are more difficult to rate in terms of identifying
the behaviours represented. It is also possible that the scale does
not sufficiently allow differentiation in these ranges. This suggests
the need for closer examination of the training process. However,
if this does not improve rating accuracy then the scale may require
further refinement. Further to this, participant ratings at the
extreme ends of the scale were highly accurate. This adds additional validity to the premise that future developments should
focus on refining ratings around the more central parts of the scale.
The proportion of correct rankings was relatively low in part
owing to the number of equal ratings for Vignettes E and F.
However, when vignettes E and F were combined into one, the
proportion of participants who ranked the vignette correctly, rose
to 76%, indicating that the equal ratings of these two vignettes was
responsible for a significant number of incorrect rank orders in the
first instance. Although in both vignettes the patient was proactive
in seeking their medication, in one (E) she initially arrived at the
wrong time. Equally high ratings of adherence were often provided owing to the lack of attention to this issue. Further to this, in
the hospital setting where training occurred, such proactive adherence tended to be viewed as highly desirable and not problematic
in relation to the relatively frequent problems with non-adherence.
Future studies might also explore the impact of occupation
and years of experience in the mental health sector, in order to
determine whether these are contributing variables to accurate
medication adherence assessment. This would shed light on the
differential training needs of mental health staff in order to ensure
that the scale is used reliably. None the less, the scale does appear
to be accessible to a range of professions with a range of experience, at least in an analogue environment. However, the utility of
the scale lies in its use and reliability in real life settings. Actual
observations of medication taking by mental health professionals
need to be rated and this needs to be compared with rates of
improvement and health gain.
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M.K. Byrne et al.
There remains some way to go before a reliable and informative
process for assessing inpatient adherence behaviour is achieved.
The present study has provided a beginning to that process and in
time should contribute to the development of clinical management
plans for inpatients in mental health facilities. More specifically, it
will allow more systematic assessment of the progress and skills
required to increase a person’s ability to more independently
manage their own medication.
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© 2009 The Authors. Journal compilation © 2009 Blackwell Publishing Ltd
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Observer rating scale of medication adherence
Appendix
Observer rating of medication-taking behaviour on the ward
Patient’s Name:___ Rater’s name:___ Date:___ Time:___
Please rate the patient’s medication adherence behaviour by rating the least adherent behaviour observed. Place a cross on the line that best
reflects their behaviour. Note: scores from 7 to 4 relate to prompting. Scores less than 4 relate to resistance.
7 = The patient always presents for their medication at the designated place and time. Never
requires prompting.
Between 6 & 7 = The patient mostly presents for their medication at the designated place &
time. Responds immediately to minimal & indirect prompting (e.g. ‘Mary, what should you
be doing now?’).
Fully adherent to
medication
7
A little
prompting
6
A lot of
prompting
5
Passively
adheres
4
6 = The patient occasionally fails to present for their medication. Responds immediately to
minimal but direct prompting (e.g. ‘Mary, it’s time to take your medication.’).
Between 5 & 6 = The patient often fails to attend for their medication but responds to direct
prompting.
5 = The patient often requires a lot of prompting and encouragement to engage in medication
taking. They only rarely self-initiate and often need help to access the medication.
Between 4 & 5 = The patient almost always needs reminding & direct prompting to get their
medication. They only rarely take responsibility for taking medication without prompting.
They may need support & prompts such as being accompanied to the clinic room, pouring a
cup of water & being handed the medication.
Adherent with prompting
No
prompting
4 = The patient passively adheres. They do not self-initiate & do not access medication
without direction. They require constant reminders but do not resist taking medication.
Between 3 & 4 = The patient occasionally delays or procrastinates when required to attend for
medication. They exhibit mild signs of resistance such as complaining to staff about medication, or nonverbal signs such as screwing up their face when swallowing tablets. They occasionally require some persuading to take their medications.
Between 2 & 3 = The patient is verbally hostile towards staff about medication taking. They
are openly resistant but comply reluctantly upon direction. Require incremental amounts of
warning from staff in order to comply. If not openly hostile & resistant, they may be covertly
resistant and may be observed trying to hide medications (e.g. ‘cheeking’ meds and pretending
to swallow).
A little
resistance
3
A lot of
resistance
2
Requires
restraint
1
2 = The patient may engage in physical intimidation towards staff or aggression directed at
property as a result of resistance around medication taking.
Between 2 & 1 = The patient is physically aggressive or resistant towards staff when refusing
to take medication. They may require presence of extra staff for safety purposes & as a back
up in case the patient requires physical restraint.
1 = Physical restraint is required in order to administer medications.
© 2009 The Authors. Journal compilation © 2009 Blackwell Publishing Ltd
Non-adherent with resistance
3 = The patient complains about medication at various times across the day (not limited to
medication taking times). They engage other patients in discussion about medications, or may
make comments that accuse staff of coercion around medication taking. Almost always require
persuading to take medications.
Fully non-adherent
to medication
251