Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and ...

COSMIC, the Catalogue of Somatic Mutations in Cancer (http://cancer.sanger.ac.uk) is a high-resolution resource for exploring targets and trends in the genetics of human cancer. Currently the broadest database of mutations in cancer, the information in COSMIC is curated by expert scientists, primarily by scrutinizing large numbers of scientific publications. Over 4 million coding mutations are described in v78 (September 2016), combining genome-wide sequencing results from 28 366 tumours with complete manual curation of 23 489 individual publications focused on 186 key genes and 286 key fusion pairs across all cancers. Molecular profiling of large tumour numbers has also allowed the annotation of more than 13 million non-coding mutations, 18 029 gene fusions, 187 429 genome rearrangements, 1 271 436 abnormal copy number segments, 9 175 462 abnormal expression variants and 7 879 142 differentially methylated CpG dinucleotides. COSMIC now details the genetics of drug resistance, novel...

Filozofske, zgodovinopisne, sociološke, politološke, kulturološke in druge raziskave totalitarizma v 20. stoletju se osredotočajo na njegovo »družbeno pojavnost«, brez uvida, da je takšna »družbena pojavnost« lahko sama totalizirajoča glede horizonta sveta kot celote bivajočega, čeprav ga jemlje kot svojo »objektivno predpostavko«. Totalitarnost kot totalitarium se opolnomočuje s postavljanjem sveta, ki ga diktira totalizacija družbene subjektivitete. Prav tako je sistem produkcije, ki ga opredeljuje tehnoznanstveni napredek in se globalno kapitalizira, potrebno dojeti v kontekstu opolnomočenja družbene subjektivitete, ki se funkcionalno »objektivira« v totalitarium. Totalitarium vzpostavljajo različni bloki in cone funkcioniranja, vendar ne v zgodovinskem zaporedju, marveč kot konjunktura urejanj, razporejanj, podrejanj in preurejanj, ki vsepovsod prevzemajo oblast.

CUPOLE . CAPPELLE . COMPOSITORI ORAZIO BENEVOLI E L’AMBIENTE MUSICALE ROMANO DEL SUO TEMPO ATTI DEL CONVEGNO INTERNAZIONALE SU ORAZIO BENEVOLI VINCENZO DI BETTA «Architettura e Canto nella Roma del Seicento», Prassi esecutiva dei cantori al tempo del magistero di Orazio Benevoli .