Morphology of neurite endings grown under different growth factor conditions

<p>Top: Percentage of neurites with only thin endings (black bars), with one or more thick endings (grey bars), and undefined (white bars) under different culture conditions A—E. Insets show the allocation of growth factors in the compartments of the culture chamber. Qualitative visual determination was done from microphotographs taken after 4 to 5 days in culture. Abbreviations indicate the growth factors (GF) in the chambers, e.g., G-N-G denotes GDNF in the lateral compartments and NGF in the central, somata-containing compartment. Bottom: Examples for thin (left) and thick (right) neurite endings are shown in microphotographs. Media conditions in the compartments as indicated. Number of animals: 3 to 5 for A—E, respectively.</p