Medial preoptic area dopaminergic responses to female pheromones develop during puberty in the male Syrian hamster

Behavioral Neuroscience, 2002

Hormones and Behavior, 1997

Physiology & Behavior, 2001

Hormones and Behavior, 1996

Physiology & Behavior, 1985

Hormones and behavior, 2000

Male sexual behavior is mediated in part by androgens, but in several species, mating is also influenced by estradiol formed locally in the brain by the aromatization of testosterone. The role of testosterone aromatization in the copulatory behavior of male Syrian hamsters is unclear because prior studies are equivocal. Therefore, the present study tested whether blocking the conversion of testosterone to estradiol would inhibit male hamster sexual behavior. Chronic systemic administration of the nonsteroidal aromatase inhibitor Fadrozole (2.0 mg/kg/day) for 5 or 8 weeks did not significantly increase mount latency or reduce mount frequency, intromission frequency, ejaculation frequency, or anogenital investigation relative to levels shown by surgical controls. However, Fadrozole effectively inhibited aromatase activity, as evidenced by the suppression of estrogen-dependent progesterone receptor immunoreactivity in the male hamster brain. The JZB39 anti-progesterone receptor antibod...

Brain Research, 1987

Hormones and Behavior, 1998

Hormones and Behavior, 2003

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