Loving the Unlovable: Simone Weil Today

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Numerical simulations and experimental methods are conducted to discover the effect of various distance between the orifice and the heated plated (L). The investigation focusing on the characteristics of convective heat transfer by a synthetic jet circular orifice. The results is verified by the time history of convective heat transfer characteristic and validated against existing experimental results. The model was simulated to investigate the dispersion of heat flow on the walls using a mathematical turbulent model of k-w SST. The Reynolds number (Re) is in the range of 1421-2843 based on average velocity, while the normalized impinging distance varies between 0 and 3.3. The movement of the piezoelectric membrane is assumed of sinusoidal wave function. The results showed the significant influence of L/d Ratio and sinusoidal wave frequencies to the heat transfer rate obtained. At small axial distance (L), average Nusselts number decrease due to confinement effect. However, at large...

A sophisticated photoactive molecular device has been prepared by combining recent concepts for the preparation of multifunctional nanomolecules (click chemistry on multifunctional scaffolds) with supramolecular chemistry (self‐assembly to prepare rotaxanes). Specifically, a clickable [2]rotaxane scaffold incorporating a free‐base porphyrin stopper has been prepared and functionalized with ten peripheral Zn(II)‐porphyrin moieties. Electrochemical investigations of the final compound revealed a peculiar behavior resulting from the intramolecular coordination of the Zn(II) porphyrin moieties to 1,2,3‐triazole units. Finally, steady state investigations of the compound combining Zn(II) and free‐base porphyrin moieties have shown that this compound is a light‐harvesting device capable of channeling the light energy from the peripheral Zn(II)‐porphyrin subunits to the core by singlet–singlet energy transfer.

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Cystic fibrosis (CF) is the most common lethal genetic disease in the Caucasian population, and should be considered an infectious disease because of the basic pathophysiology. Chronic lower airway infections cause a progressive pathologic deterioration of lung tissue, a decline in pulmonary function and, ultimately, respiratory failure and death in 90% of CF patients. Historically, very few bacterial species have been implicated as principal CF pathogens. However, molecular evidence suggests the presence of a diverse mosaic of bacteria in CF lungs, and infections can be defined as polymicrobial. Here we review the work that supports this concept and we discuss the potential significance of the polymicrobial community in lung pathology. Understanding the dynamics of polymicrobial infections, the interplay between pathogen(s), normal oropharyngeal flora and the host immune system may lead to future advances in the therapeutic management of chronic lung infections.