Blindness, ophthalmoplegia and extensive radiculopathy: an unusual clinical syndrome in intracranial sino-venous thrombosis

BMC neurology, 2018

Cerebral venous sinus thrombosis or stenosis (here collectively referred to as cerebral venous sinus occlusion, CVSO) can cause chronically-elevated intracranial pressure (ICP). Patients may have no neurological symptoms other than visual impairment, secondary to bilateral papilledema. Correctly recognizing these conditions, through proper ophthalmological examination and brain imaging, is very important to avoid delayed diagnosis and treatment. We report a case series of 3 patients with chronic CVSO, who were admitted to an ophthalmological department in Chongqing, China, from 2015 March to 2017 February. All patients presented with decreased vision and bilateral papilledema, but had no headache or other neurological symptoms. The visual fields of all patients were impaired. Flash visual evoked potentials (VEPs) in two patients showed essentially normal peak time of P2 wave, and pattern VEPs in one patient displayed decreased P100 amplitude in one eye, while a normal P100 wave in t...

IP Innovative Publication Pvt. Ltd., 2019

Aim: To study the ocular manifestations in cerebral venous thrombosis. Materials and Methods: We report a case of a 25-year- old married woman who presented to medical emergency with frank per rectal bleeding and later after two days complained of blurring of vision in both eyes and binocular diplopia. On probing the patient, she also gave history of on and off headache since 6 months. Results: MRI Brain with Venogram was suggestive of intracranial hypertension and non-occlusive thrombus in bilateral transverse and sigmoid sinuses. Conclusion: CVT should be kept in mind in any patient with acute onset of diplopia with papilledema or cranial nerve involvement. Acute blood loss with severe anaemia can precipitate CVT. Imaging modalities like MRI with venogram should be the investigation of choice in all cases of CVT. Keywords: Cerebral venous thrombosis, Diplopia, Papilloedema, Transverse sinus, Sigmoid sinus and intracranial hypertension

Journal of the Neurological Sciences, 2003

Ophthalmology, 2006

2016

Clinical presentation of cerebral venous sinus thrombosis (CVST) is varied and often mimics many neurological disorders, making it a diagnostic challenge, and cranial nerve palsy in CVST is rare and its pathophysiology remains unclear. We report a case of a 19-year-old male with a history of whiplash injury, admitted with extensive CVST, developed right facial nerve palsy with extension of thrombus into the ipsilateral transverse sinus, sigmoid sinus and internal jugular vein. Later, he developed left facial nerve palsy with partial left occulomotor weakness. We suggest that either reversible compromised oxygen or glucose consumption within the intrinsic vascular system of the nerve, resulting in cranial nerve abnormalities. CVST should be con-sidered in cases of trivial trauma, even in the absence of hyper-coagulable states, and it can have atypical presentation like multiple cranial neuropathies.

Journal of Clinical Neuroscience, 2009

Oxford Medical Case Reports, 2014

Ağrı - The Journal of The Turkish Society of Algology, 2013

Journal of Clinical Neuroscience, 2009

2020

Cerebral Venous Thrombosis (CVT) and Idiopathic Intracranial Hypertension (IIH) are always to be considered in patients with isolated intracranial hypertension. We report a patient with progressive visual loss, ophthalmoplegia and polyradiculopathy with are flexic quadriparesis, secondary to raised intracranial pressure (ICP). Quadriparesis due to raised ICP is a rarely reported presentation.