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Can ageing be stopped? A biologist explains
30:43|For millennia, humanity has obsessed about halting ageing and, ultimately, preventing death. Yet while advances in medicine and public-health have seen human life-expectancy more than double, our maximum lifespan stubbornly remains around 120 years.On the latest episode of Nature hits the books, Nobel laureate Venki Ramakrishnan joins us to discuss what scientists have learnt about the molecular processes underlying ageing, whether they can be prevented, and why the quest for longevity also needs to consider the health-related issues associated with old age.Why We Die: The New Science of Ageing and the Quest for Immortality Venki Ramakrishnan Hodder (2024)Music supplied by Airae/Epidemic Sound/Getty images.
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AI can't learn new things forever — an algorithm can fix that
19:50|00:46 Old AIs can’t learn new tricksAn algorithm that reactivates dormant ‘neurons’ in deep learning based AIs could help them overcome their inability to learn new things and make future systems more flexible, research has shown. AIs based on deep learning struggle to learn how to tackle new tasks indefinitely, making them less adaptable to new situations. The reasons for this are unclear, but now a team has identified that ‘resetting’ parts of the neural networks underlying these systems can allow deep learning methods to keep learning continually.Research Article: Dohare et al.News and Views: Switching between tasks can cause AI to lose the ability to learn08:55 Research HighlightsTo stop crocodiles eating poisonous toads researchers have been making them sick, and a sacrificed child in ancient Mexico was the progeny of closely related parents.Research Highlight: How to train your crocodileResearch Highlight: DNA of child sacrificed in ancient city reveals surprising parentage11:20 Briefing ChatHow video games gave people a mental health boost during the pandemic, and where the dinosaur-destroying Chicxulub asteroid formed.Nature News: PlayStation is good for you: video games improved mental health during COVIDNature News: Dinosaur-killing Chicxulub asteroid formed in Solar System’s outer reachesSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.The mystery of Stonehenge's central stone unearthed
22:49|00:48 The mystery of Stonehenge’s Altar StoneStonehenge’s central stone came from Northern Scotland, more than 600 miles away from the monument, according to a new analysis of its geochemistry. It is commonly accepted that many of the rocks that make up the iconic neolithic monument came from Wales, 150 miles from the site. Previously, it had been thought that a central stone, called the Altar Stone, had also come from this area, known as the Preseli Hills. The new work suggests that the ancient Britons went much further, perhaps ferrying the Altar Stone hundreds of miles, to place the rock at the centre of Stonehenge.Research Article: Clarke et al.News: Stonehenge’s massive slabs came from as far as Scotland — 800 kilometres away12:12 Research HighlightsHow a parasite could help scientists break through the blood-brain barrier, and the physics of skateboard moves.Research Highlight: Engineered brain parasite ferries useful proteins into neuronsResearch Highlight: How expert skateboarders use physics on the half-pipe14:13 A new way to break bondsChemists have demonstrated a way to break Selenium-Selenium bonds unevenly, something they have been trying for decades. Chemical bonds have to be broken and reformed to create new compounds, but they often don’t break in a way that allows chemists to form new bonds in the ways they would like. Breaks are often ‘even’, with electrons shared equally between atoms. To prevent such an even split, a team used a specific solvent and a combination of light and heat to force the selenium bonds to break unevenly. This could potentially open up ways to create compounds that have never been made before.Research Article: Tiefel et al.News and Views: Innovative way to break chemical bonds broadens horizons for making moleculesSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.ChatGPT has a language problem — but science can fix it
36:50|AIs built on Large Language Models have wowed by producing particularly fluent text. However, their ability to do this is limited in many languages. As the data and resources used to train a model in a specific language drops, so does the performance of the model, meaning that for some languages the AIs are effectively useless.Researchers are aware of this problem and are trying to find solutions, but the challenge extends far beyond just the technical, with moral and social questions to be answered. This podcast explores how Large Language Models could be improved in more languages and the issues that could be caused if they are not.Watch our related video of people trying out ChatGPT in different languages.Where weird plants thrive: aridity spurs diversity of traits
26:09|00:48 Plant trait diversity in drylandsA study reveals that, unexpectedly, plants display a greater diversity of traits in drier environments. Trait diversity is a measure of an organism's performance in an environment and can include things like the size of a plant or its photosynthetic rate. Whilst there are good data on this kind of diversity in temperate regions, an assessment of drylands has been lacking. The new study fills this knowledge gap and finds that, counter to a prevailing expectation that fewer traits would be displayed, at a certain level of aridity trait diversity doubles. The team behind the new work hope that it can help us better protect biodiversity as the planet warms and areas become drier.Research Article: Gross et al.08:25 Research HighlightsButterflies and moths use static charge to pick up pollen, and quantum physics rules out black holes made of light.Research Highlight: Charged-up butterflies draw pollen through the airResearch Highlight: Black holes made from light? Impossible, say physicists10:59 The Great Barrier Reef is the hottest it’s been for centuriesAn assessment of coral skeletons has shown that the past decade has been the warmest for the Great Barrier Reef for 400 years. By looking at the chemical composition of particularly old specimens of coral in the reef, researchers were able to create a record of temperatures going back to 1618. In addition to showing recent record breaking temperatures they also developed a model that suggests that such temperatures are very unlikely to occur without human-induced climate change. Altogether, the study suggests that the reef is in dire straits and much of the worlds’ coral could be lost.Research Article: Henley et al.News and Views: Coral giants sound the alarm for the Great Barrier ReefNature News: Great Barrier Reef's temperature soars to 400-year high18:56 ‘Publish or Perish’ becomes a card gameMost researchers are familiar with the refrain ‘Publish or Perish’ — the idea that publications are the core currency of a scientist’s career — but now that can be played out for laughs in a new board game. Created as a way to help researchers “bond over shared trauma”, the game features many mishaps familiar to academics, scrambles for funding and scathing comments, all while players must compete to get the most citations on their publications. Reporter Max Kozlov set out to avoid perishing and published his way to a story about the game for the Nature Podcast.Nature News: ‘Publish or Perish’ is now a card game — not just an academic’s lifeSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.How light-based computers could cut AI’s energy needs
32:37|00:45 Increasing the energy efficiency of light-based computersComputer components based on specialised LEDs could reduce the energy consumption of power hungry AI systems, according to new research. AI chips with components that compute using light can run more efficiently than those using digital electronics, but these light-based systems typically use lasers that can be bulky and difficult to control. To overcome these obstacles, a team has developed a way to replace these lasers with LEDs, which are cheaper and more efficient to run. Although only a proof of concept, they demonstrate that their system can perform some tasks as well as laser-based computers.Research Article: Dong et al.News and Views: Cheap light sources could make AI more energy efficient10:36 Research HighlightsThe genes that make roses smell so sweet, and how blocking inflammation could reduce heart injury after a stroke.Research Highlight: How the rose got its iconic fragranceResearch Highlight: Strokes can damage the heart — but reining in the immune system might help13:02 What researchers know about H5N1 influenza in cowsThe highly-pathogenic avian influenza H5N1 was first identified in US cattle in March 2024 and has been detected in multiple herds across the country. We round up what researchers currently know about this spread, what can be done to prevent it, and the risks this outbreak may pose to humans.Nature News: Can H5N1 spread through cow sneezes? Experiment offers cluesNature News: Huge amounts of bird-flu virus found in raw milk of infected cowsNature News: Could bird flu in cows lead to a human outbreak? Slow response worries scientistsResearch article: Eisfeld et al.22:38 Briefing ChatNASA’s Perseverance rover finds a Martian rock containing features associated with fossilized microbial life, and how metallic nodules on the ocean floor could be the source of mysterious ‘dark oxygen’Space.com: NASA's Perseverance Mars rover finds possible signs of ancient Red Planet lifeNature News: Mystery oxygen source discovered on the sea floor — bewildering scientistsSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.Audio long read: Hope, despair and CRISPR — the race to save one woman’s life
23:04|In India, a group of researchers raced to develop a CRISPR-based genome editing therapy to save the life of a young woman with a rare neurodegenerative disease. Despite a valiant effort, the pace of research was ultimately too slow to save her life. While many are convinced that these therapies could offer hope to those with overlooked genetic conditions, it will likely take years to develop the techniques needed to quickly create bespoke treatments, something people in need don't have.This is an audio version of our Feature: Hope, despair and CRISPR — the race to save one woman’s life