Database: Pfam
Entry: PH_14
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Entry: PH_14
LinkDB: PH_14
Original site: PH_14
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Gene (4538) KEGG GENES (4538) Protein sequence (7063) UniProt (7048) SWISS-PROT (15) 3D Structure (7) PDB (7) Protein domain (2) InterPro (1) NCBI-CDD (1) Literature (1) PubMed (1) All databases (11611)
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#=GF ID PH_14 #=GF AC PF17787.6 #=GF DE PH domain #=GF AU Bateman A;0000-0002-6982-4660 #=GF SE ECOD:EUF00649 #=GF GA 22.70 22.70; #=GF TC 22.70 22.70; #=GF NC 22.60 22.60; #=GF BM hmmbuild HMM.ann SEED.ann #=GF SM hmmsearch -E 1000 -Z 81514348 --cpu 4 HMM pfamseq #=GF TP Domain #=GF WK Pleckstrin_homology_domain #=GF CL CL0266 #=GF RN [1] #=GF RM 18691970 #=GF RT General and versatile autoinhibition of PLC isozymes. #=GF RA Hicks SN, Jezyk MR, Gershburg S, Seifert JP, Harden TK, Sondek #=GF RA J; #=GF RL Mol Cell. 2008;31:383-394. #=GF DR INTERPRO; IPR037862; #=GF DR SO; 0000417; polypeptide_domain; #=GF CC This entry corresponds to the PH domain found at the N-terminus #=GF CC of phospholipase C enzymes [1]. #=GF SQ 5181 #=GS A0A851LU19_CORCR/27-115 AC A0A851LU19.1 #=GS A0A8C5B0B9_GADMO/37-134 AC A0A8C5B0B9.1 #=GS A0A6P7LD99_BETSP/17-147 AC A0A6P7LD99.1 #=GS A0A8P4FWG3_DICLA/12-138 AC A0A8P4FWG3.1 #=GS A0A6P7LRT9_BETSP/12-140 AC A0A6P7LRT9.1 #=GS A0A6P6MKV9_CARAU/12-140 AC A0A6P6MKV9.1 #=GS T1K582_TETUR/17-105 AC T1K582.2 #=GS A0A7K8W1M5_9FURN/12-140 AC A0A7K8W1M5.1 #=GS A0A0C9RU63_9HYME/12-140 AC A0A0C9RU63.1 #=GS A0A2K5JZJ5_COLAP/12-140 AC A0A2K5JZJ5.1 #=GS A0A556TSN3_BAGYA/87-178 AC A0A556TSN3.1 #=GS A0A4U1EPR5_MONMO/165-255 AC A0A4U1EPR5.1 #=GS A0A8C2WRC7_CYCLU/17-146 AC A0A8C2WRC7.1 #=GS A0A7M7GZL3_APIME/17-145 AC A0A7M7GZL3.1 #=GS A0A8C8LRL8_ONCTS/17-151 AC A0A8C8LRL8.1 #=GS A0A6P6NMV4_CARAU/1-103 AC A0A6P6NMV4.1 #=GS A0A7M7Q185_NASVI/12-140 AC A0A7M7Q185.1 #=GS A0A0V1DE59_TRIBR/27-81 AC A0A0V1DE59.1 #=GS A0A915EH13_9BILA/14-141 AC A0A915EH13.1 #=GS U3EKX0_CALJA/17-145 AC U3EKX0.1 #=GS PLCB2_HUMAN/12-141 AC Q00722.2 #=GS PLCB2_HUMAN/12-141 DR PDB; 2ZKM X; 12-141; #=GS PLCB2_HUMAN/12-141 DR PDB; 2FJU B; 12-141; #=GS A0A2K5VG05_MACFA/17-145 AC A0A2K5VG05.2 #=GS A0A094KQS7_ANTCR/12-140 AC A0A094KQS7.1 #=GS A0A0V0SNT3_9BILA/12-141 AC A0A0V0SNT3.1 #=GS A0A8C9FAI0_PAVCR/12-141 AC A0A8C9FAI0.1 #=GS L9KP95_TUPCH/12-140 AC L9KP95.1 #=GS A0A9C6U2J9_FRAOC/12-138 AC A0A9C6U2J9.1 #=GS A0A7J8ETH7_MOLMO/17-97 AC A0A7J8ETH7.1 #=GS A0A669P7N2_PHACC/17-146 AC A0A669P7N2.1 #=GS A0A6J8CYN3_MYTCO/17-146 AC A0A6J8CYN3.1 #=GS A0A8C3WTC2_9CETA/17-145 AC A0A8C3WTC2.1 #=GS A0A7L4A626_9AVES/1-65 AC A0A7L4A626.1 #=GS A0A8C3Y761_CATUS/12-140 AC A0A8C3Y761.1 #=GS A0A5C6NQ66_9TELE/12-140 AC A0A5C6NQ66.1 #=GS A0A8C7J9S0_ONCKI/17-146 AC A0A8C7J9S0.1 #=GS A0A9W2XJT2_BETSP/72-201 AC A0A9W2XJT2.1 #=GS A0A0V0SNS4_9BILA/20-156 AC A0A0V0SNS4.1 #=GS A0A7K5MN53_CARCD/27-115 AC A0A7K5MN53.1 #=GS V3Z4D6_LOTGI/12-55 AC V3Z4D6.1 #=GS A0A4U5UQR2_COLLU/12-140 AC A0A4U5UQR2.1 #=GS A0A2G5SIG8_9PELO/2-134 AC A0A2G5SIG8.1 #=GS A0A7L2V284_9AVES/28-115 AC A0A7L2V284.1 #=GS A0A3P9B211_9CICH/17-145 AC A0A3P9B211.1 #=GS A0A9J7WW98_CYPCA/17-146 AC A0A9J7WW98.1 #=GS A0A671TVZ7_SPAAU/1-118 AC A0A671TVZ7.1 #=GS A0A663F7M6_AQUCH/12-141 AC A0A663F7M6.1 #=GS A0A8C4WLZ0_9SAUR/12-140 AC A0A8C4WLZ0.1 #=GS A0A6I9LSY7_PERMB/12-140 AC A0A6I9LSY7.1 #=GS A0A8C6LEU0_NOTFU/12-138 AC A0A8C6LEU0.1 #=GS A0A672RSS7_SINGR/12-132 AC A0A672RSS7.1 #=GS B4NP83_DROWI/12-146 AC B4NP83.1 #=GS A0A2Y9LAV2_ENHLU/12-141 AC A0A2Y9LAV2.1 #=GS A0A099ZSA6_TINGU/1-65 AC A0A099ZSA6.1 #=GS A0A4W4F5C9_ELEEL/17-123 AC A0A4W4F5C9.1 #=GS A0A6P3WQ17_DINQU/12-140 AC A0A6P3WQ17.1 #=GS A0A7K8SWB8_9AVES/27-115 AC A0A7K8SWB8.1 #=GS A0A6A1QAR2_BALPH/472-579 AC A0A6A1QAR2.1 #=GS A0A158QYI0_NIPBR/12-139 AC A0A158QYI0.1 #=GS A0A226MLG7_CALSU/118-213 AC A0A226MLG7.1 #=GS A0A668UZT5_OREAU/17-140 AC A0A668UZT5.1 #=GS A0A7J8AP19_MYOMY/12-141 AC A0A7J8AP19.1 #=GS A0A8C5NM67_JUNHY/12-141 AC A0A8C5NM67.1 #=GS A0A6Q2WVL9_ESOLU/17-147 AC A0A6Q2WVL9.1 #=GS A0A814KBM8_9BILA/19-149 AC A0A814KBM8.1 #=GS A0A5N4APM4_PHOPY/65-192 AC A0A5N4APM4.1 #=GS A0A8C3C3V5_CAIMO/29-157 AC A0A8C3C3V5.1 #=GS A0A671M6D0_9TELE/12-140 AC A0A671M6D0.1 #=GS A0A6H5G9W6_9HEMI/12-140 AC A0A6H5G9W6.1 #=GS A0A2K6BBN4_MACNE/12-140 AC A0A2K6BBN4.1 #=GS A0A8C0USB2_CYACU/7-124 AC A0A8C0USB2.1 #=GS A0A8J1KM03_XENLA/61-189 AC A0A8J1KM03.1 #=GS H2NMT9_PONAB/12-141 AC H2NMT9.3 #=GS A0A8B8DPZ3_CRAVI/12-140 AC A0A8B8DPZ3.1 #=GS A0A7L1Z330_9PASS/1-65 AC A0A7L1Z330.1 #=GS K7FQ96_PELSI/1-65 AC K7FQ96.1 #=GS A0A674IVL4_TERCA/1-48 AC A0A674IVL4.1 #=GS A0A914N264_MELIC/16-150 AC A0A914N264.1 #=GS A0A7L2EKF4_ANTMN/28-115 AC A0A7L2EKF4.1 #=GS A0A8C9LHQ2_9PRIM/17-145 AC A0A8C9LHQ2.1 #=GS A0A672HK23_SALFA/59-127 AC A0A672HK23.1 #=GS A0A914DGM1_9BILA/12-138 AC A0A914DGM1.1 #=GS A0A482W360_9CUCU/1-112 AC A0A482W360.1 #=GS A0A7K8EUX0_LEURO/1-65 AC A0A7K8EUX0.1 #=GS E2AT88_CAMFO/18-146 AC E2AT88.1 #=GS A0A0Q9WRM6_DROWI/15-143 AC A0A0Q9WRM6.1 #=GS A0A452FUL5_CAPHI/12-140 AC A0A452FUL5.1 #=GS A0A914Q223_9BILA/12-139 AC A0A914Q223.1 #=GS A0A7L1J535_SMUAF/12-140 AC A0A7L1J535.1 #=GS A0A813PHA6_ADIRI/12-142 AC A0A813PHA6.1 #=GS A0A7K6BW10_PTIVI/1-65 AC A0A7K6BW10.1 #=GS A0A3Q1HI38_ANATE/12-141 AC A0A3Q1HI38.1 #=GS B4GTC4_DROPE/12-146 AC B4GTC4.1 #=GS A0A452RJS0_URSAM/1-88 AC A0A452RJS0.1 #=GS A0A7K6GA55_9PASS/12-140 AC A0A7K6GA55.1 #=GS A0A6J1N444_BICAN/12-140 AC A0A6J1N444.1 #=GS A0A7J8HK98_MOLMO/12-140 AC A0A7J8HK98.1 #=GS A0A674E0G8_SALTR/6-60 AC A0A674E0G8.1 #=GS A0A6J1N9A1_BICAN/12-140 AC A0A6J1N9A1.1 #=GS A0A484C937_PERFV/17-146 AC A0A484C937.1 #=GS A0A8C4ZFX6_GADMO/13-142 AC A0A8C4ZFX6.1 #=GS A0A6P4JTS1_DROKI/15-143 AC A0A6P4JTS1.1 #=GS G3WSF6_SARHA/17-145 AC G3WSF6.2 #=GS A0A7I8X6Z8_BURXY/12-139 AC A0A7I8X6Z8.1 #=GS A0A4W6DVB6_LATCA/12-138 AC A0A4W6DVB6.1 #=GS A0A8V5FIJ1_MELUD/21-89 AC A0A8V5FIJ1.1 #=GS A0A671TWJ6_SPAAU/12-138 AC A0A671TWJ6.1 #=GS A0A673LNK5_9TELE/17-145 AC A0A673LNK5.1 #=GS A0A8C4HMK0_DICLA/17-148 AC A0A8C4HMK0.2 #=GS A0A851KJQ5_VIDCH/1-65 AC A0A851KJQ5.1 #=GS A0A2G5SIS2_9PELO/141-273 AC A0A2G5SIS2.1 #=GS S7N7A1_MYOBR/1-44 AC S7N7A1.1 #=GS A0A8C5ACB8_GADMO/17-146 AC A0A8C5ACB8.1 #=GS W5KF50_ASTMX/2-69 AC W5KF50.2 #=GS A0A672UU43_STRHB/12-140 AC A0A672UU43.1 #=GS A0A8C6WR70_9GOBI/17-136 AC A0A8C6WR70.1 #=GS A0A0K3AS85_CAEEL/13-139 AC A0A0K3AS85.1 #=GS A0A8J4K7S8_EUDMI/1-65 AC A0A8J4K7S8.1 #=GS A0A7L1WVD1_9PASS/12-140 AC A0A7L1WVD1.1 #=GS A0A7R8YW92_HERIL/12-143 AC A0A7R8YW92.1 #=GS A0A2Y9PNQ6_DELLE/17-146 AC A0A2Y9PNQ6.1 #=GS A0A7J7YAB7_PIPKU/17-145 AC A0A7J7YAB7.1 #=GS A0A8C3B883_CAIMO/12-141 AC A0A8C3B883.1 #=GS A0A7L1UC97_PHANI/12-140 AC A0A7L1UC97.1 #=GS A0A7K9WV73_9PASS/28-115 AC A0A7K9WV73.1 #=GS A0A2A6C807_PRIPA/27-167 AC A0A2A6C807.1 #=GS A0A2Y9DZ23_TRIMA/17-145 AC A0A2Y9DZ23.1 #=GS A0A6P8WBW6_DROAB/15-143 AC A0A6P8WBW6.1 #=GS A0A8J4LJJ4_APTPA/27-115 AC A0A8J4LJJ4.1 #=GS A0A7M7HA58_NASVI/12-141 AC A0A7M7HA58.1 #=GS A0A7L4DZG3_HIRRU/1-62 AC A0A7L4DZG3.1 #=GS A0A3Q2W1J8_HAPBU/7-77 AC A0A3Q2W1J8.1 #=GS A0A668UXT2_OREAU/4-115 AC A0A668UXT2.1 #=GS A0A8C9I9K2_9PRIM/12-141 AC A0A8C9I9K2.1 #=GS A0A6P3H2P4_BISBB/17-146 AC A0A6P3H2P4.1 #=GS A0A7K8AQ81_9CORV/1-65 AC A0A7K8AQ81.1 #=GS A0A484AND0_DRONA/12-80 AC A0A484AND0.1 #=GS A0A8B9Z3X9_9AVES/12-141 AC A0A8B9Z3X9.1 #=GS A0A0V1DE17_TRIBR/27-156 AC A0A0V1DE17.1 #=GS A0A2J8SU37_PONAB/17-145 AC A0A2J8SU37.1 #=GS A0A914RF72_PAREQ/14-80 AC A0A914RF72.1 #=GS A0A3Q0G1M2_ALLSI/12-141 AC A0A3Q0G1M2.1 #=GS A0A834JZ69_VESPE/12-140 AC A0A834JZ69.1 #=GS A0A673WU36_SALTR/12-140 AC A0A673WU36.1 #=GS A0A834R4D7_SARSC/12-146 AC A0A834R4D7.1 #=GS A0A4C1S8C4_EUMVA/16-107 AC A0A4C1S8C4.1 #=GS A0A8C4BJC4_9TELE/17-63 AC A0A8C4BJC4.1 #=GS A0A669Q932_PHACC/12-141 AC A0A669Q932.1 #=GS A0A2Y9SLA6_PHYMC/17-145 AC A0A2Y9SLA6.1 #=GS A0A1I8MB42_MUSDO/14-142 AC A0A1I8MB42.1 #=GS A0A3Q3FKF9_9LABR/17-148 AC A0A3Q3FKF9.1 #=GS A0A2K5MNP8_CERAT/12-140 AC A0A2K5MNP8.1 #=GS A0A665V562_ECHNA/12-65 AC A0A665V562.1 #=GS A0A6J0DT19_PERMB/12-140 AC A0A6J0DT19.1 #=GS A0A8C5MSV2_9ANUR/12-140 AC A0A8C5MSV2.1 #=GS A0A1U7QB61_MESAU/17-138 AC A0A1U7QB61.1 #=GS A0A6I8N5N0_ORNAN/1-92 AC A0A6I8N5N0.1 #=GS A0A2K5BXT9_AOTNA/12-140 AC A0A2K5BXT9.1 #=GS A0A8C5IAP3_9TELE/17-136 AC A0A8C5IAP3.1 #=GS A0A267G433_9PLAT/25-150 AC A0A267G433.1 #=GS A0A852CNN8_9PICI/1-65 AC A0A852CNN8.1 #=GS A0A9D3N844_9TELE/12-140 AC A0A9D3N844.1 #=GS A0A7M7J5X8_VARDE/4-75 AC A0A7M7J5X8.1 #=GS I3IX38_ORENI/4-73 AC I3IX38.2 #=GS A0A7K6UW13_9PASS/23-115 AC A0A7K6UW13.1 #=GS A0A7K8G7P4_ORTSP/12-140 AC A0A7K8G7P4.1 #=GS A0A8B8ILP7_VANTA/12-140 AC A0A8B8ILP7.1 #=GS A0A8X6XT75_9ARAC/17-146 AC A0A8X6XT75.1 #=GS A0A7R8YMU2_HERIL/14-142 AC A0A7R8YMU2.1 #=GS A0A8U0P5F3_SALNM/12-140 AC A0A8U0P5F3.1 #=GS A0A8C4III3_DICLA/12-59 AC A0A8C4III3.2 #=GS A0A7K8G5C1_ORTSP/1-87 AC A0A7K8G5C1.1 #=GS A0A2R9BYE2_PANPA/12-141 AC A0A2R9BYE2.1 #=GS A0A7N6A642_ANATE/1-113 AC A0A7N6A642.1 #=GS A0A8C9X896_SANLU/17-143 AC A0A8C9X896.1 #=GS A0A673LTS1_9TELE/69-139 AC A0A673LTS1.1 #=GS A0A4Z2BSC7_9TELE/17-146 AC A0A4Z2BSC7.1 #=GS A0A0Q9XI68_DROMO/15-143 AC A0A0Q9XI68.1 #=GS A0A8C4ZYH9_GADMO/12-140 AC A0A8C4ZYH9.1 #=GS A0A914LMF1_MELIC/16-150 AC A0A914LMF1.1 #=GS A0A8C9NGH3_SERCA/14-83 AC A0A8C9NGH3.1 #=GS A0A8C6H0J6_MUSSI/12-141 AC A0A8C6H0J6.1 #=GS A0A6P8GL64_CLUHA/12-139 AC A0A6P8GL64.1 #=GS A0A3Q3MZX7_9TELE/2-68 AC A0A3Q3MZX7.2 #=GS A0A674P8D5_TAKRU/58-123 AC A0A674P8D5.1 #=GS A0A914K7G8_9BILA/12-139 AC A0A914K7G8.1 #=GS A0A914YCU6_9BILA/12-139 AC A0A914YCU6.1 #=GS A0A915GBT5_9BILA/8-139 AC A0A915GBT5.1 #=GS A0A7N4P6S8_SARHA/25-154 AC A0A7N4P6S8.1 #=GS A0A3Q1DBS8_AMPOC/12-141 AC A0A3Q1DBS8.1 #=GS A0A8C4HNX0_DICLA/17-148 AC A0A8C4HNX0.1 #=GS A0A671Q3R3_9TELE/17-146 AC A0A671Q3R3.1 #=GS H3BYJ8_TETNG/3-122 AC H3BYJ8.1 #=GS A0A091DX70_FUKDA/12-140 AC A0A091DX70.1 #=GS A0A9J8CWB3_CYPCA/17-147 AC A0A9J8CWB3.1 #=GS A0A8C6W2A8_NANGA/12-141 AC A0A8C6W2A8.1 #=GS A0A7K6E8Z0_9PASS/28-115 AC A0A7K6E8Z0.1 #=GS A0A7J6AM14_AMEME/12-141 AC A0A7J6AM14.1 #=GS A0A091NGE7_APAVI/1-113 AC A0A091NGE7.1 #=GS A0A7L2ZPI6_9PASE/28-115 AC A0A7L2ZPI6.1 #=GS A0A8C6LDM1_NOTFU/12-138 AC A0A8C6LDM1.1 #=GS A0A1S3MAI8_SALSA/12-140 AC A0A1S3MAI8.1 #=GS A0A8C5N5W3_9TELE/12-143 AC A0A8C5N5W3.1 #=GS A0A674NMB2_TAKRU/17-146 AC A0A674NMB2.1 #=GS A0A8D2FE64_THEGE/12-140 AC A0A8D2FE64.1 #=GS A0A7J8HJR4_MOLMO/17-63 AC A0A7J8HJR4.1 #=GS A0A8C1I0X0_CYPCA/4-128 AC A0A8C1I0X0.2 #=GS 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