Apr 14, 2015 · This paper addresses the challenging problem of 3D reconstruction from 2D Cryo-EM images. A new framework for estimation is introduced which relies on modern ...

Discovering the 3D atomic structure of molecules such as proteins and viruses is a fundamental research problem in biology and medicine.

requiring two weeks on 300 cores to process a dataset with. 200,000 images. We introduce a framework for Cryo-EM density estima-.

Discovering the 3D atomic structure of molecules such as proteins and viruses is a fundamental research problem in biology and medicine. Electron Cry-.

Use of this in academic publications should cite: "Building Proteins in a Day: Efficient 3D Molecular Reconstruction" by Marcus A. Brubaker, Ali Punjani and ...

Supplementary Material for: Building Proteins in a Day: Efficient 3D Molecular Reconstruction. Marcus A. Brubaker, Ali Punjani and David J. Fleet. University ...

A new framework for estimation is introduced which relies on modern stochastic optimization techniques to scale to large datasets and reduces the cost of ...

The approach is remarkably efficient,. providing useful low resolution density estimates in an hour. ... tions on two real datasets and one synthetic dataset.

Transmission electron microscopy (TEM) is a powerful technique for visualizing structure at nanometer or Angstrom resolution. However, multiple factors reduce ...

Building proteins in a day: Efficient 3D molecular reconstruction. Brubaker, M. A., Punjani, A., & Fleet, D. J. In IEEE Conference on Computer Vision and ...