Aug 8, 2024 · We develop a framework to detect perturbation-dependent changes in polyadenylation and characterize modules of co-regulated polyA sites.
Aug 19, 2024 · A number of computational methods have been developed to predict these cis-regulatory elements, either by matching mRNA sequence with experimentally ...
Aug 27, 2024 · This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition.
Aug 12, 2024 · HNRNPL directly regulates the alternative splicing of a set of RNAs, including those encoding the androgen receptor, the key lineage-specific prostate cancer ...
Aug 27, 2024 · The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and ...
Aug 5, 2024 · The study highlights that CPSF6's phase separation behavior, rather than its expression level, is crucial in regulating alternative polyadenylation and ...
Aug 15, 2024 · Predicting nuclear G-quadruplex RNA-binding proteins with roles in transcription and phase separation. RNA G-quadruplexes are important regulatory elements ...
Aug 9, 2024 · This work reveals intricate involvement of TIRR in orchestrating mRNA nuclear export and storage within PBs, emphasizing its significance in the regulation of ...
Missing: Elements. | Show results with:Elements.
Aug 22, 2024 · The Rajewsky lab studies how RNA regulates gene expression in health and disease. We are collaborating with various clinicians and have built up human brain ...
Aug 20, 2024 · Poly(A)-tail profiling reveals an embryonic switch in translational control. Nature 508:66-71. Supplemental Material. Nam, J-W, O.S. Rissland, D. Koppstein ...