A probabilistic model, CPEDetector, is presented for predicting whether or not a gene's translation is mediated by CPEB. CPEDetector takes into account detected ...
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Abstract. Cytoplasmic post-transcriptional modification of mRNA transcripts in the form of polyadenylated (poly(A)) tails plays a key role in their transla-.
A polyadenylation element that functions early in oocyte maturation, the polyadenylation response element (PRE), was predicted computationally [15,16]. The ...
Gene expression during oocyte maturation is controlled by cytoplasmic polyadenylation of stored mRNAs (Mendez and Richter 2001). During transcription, mRNAs ...
Jun 14, 2013 · The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA. Mol Cell Biol ...
Feb 8, 2008 · Cytoplasmic polyadenylation plays a key role in the translational control of mRNAs driving biological pro- cesses such as gametogenesis, ...
ABSTRACT. Most cells change patterns of gene expression through transcriptional regulation. In contrast, oocytes are transcriptionally.
Nov 18, 2016 · GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells.
Jul 24, 2019 · Collectively, our data show that changes in mRNA polyadenylation are a key mechanism regulating protein expression during vertebrate oocyte ...
The polyadenylation-regulated translation is controlled by the cytoplasmic polyadenylation element (CPE) and its binding protein, CPEB, which can assemble ...