Genotype imputation has been widely utilized for two reasons in the analysis of Genome-Wide Association Studies (GWAS). One reason is to increase the power ...
May 23, 2018 · of genetic variants, which increases the chance of imputing a causal variant, and better imputation accuracy, which improves the power of ...
Nov 23, 2022 · Recent advances in genome sequencing technologies and improvement in genotype imputation accuracy enable large-scale genetic studies with ...
To optimize imputation accuracy one has to find a balance between representing as much of the genetic diversity as possible while avoiding the introduction of ...
Yue Wu, Farhad Hormozdiari, Jong Wha J. Joo, Eleazar Eskin: Improving Imputation Accuracy by Inferring Causal Variants in Genetic Studies.
The hazards of genotype imputation when mapping disease ...
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Jan 3, 2024 · Variants within the region of the well-known lactase gene (LCT), which have become frequent in a limited number of modern populations due to ...
However, the genetic sequences involve people's privacy, confirming an individual's identification and even disease information. This work proposes a secure ...
Missing: Inferring | Show results with:Inferring
Genotype imputation has been widely utilized for two reasons in the analysis of genome-wide association studies (GWAS). One reason is to increase the power ...
Motivation: Imputation using external reference panels (e.g. 1000 Genomes) is a widely used approach for increasing power in genome-wide association studies and ...
Genotype imputation hence helps tremendously in narrowing down the location of probably causal variants in genome-wide association studies, because it ...