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Genotype imputation has been widely utilized for two reasons in the analysis of genome-wide association studies (GWAS). One reason is to increase the power ...
Nov 7, 2019 · The standard way of utilizing imputation in the GWAS analysis is to impute the genotypes and compute the summary statistics from the imputed ...
Abstract Genotype imputation has been widely utilized for two reasons in the analysis of genome-wide association studies (GWAS). One reason is to increase ...
Improving Imputation Accuracy by Inferring Causal Variants in Genetic Studies. ; Journal. J Comput Biol ; Volume. 26 ; Issue. 11 ; Pages. 1203-1213 ; Date Published.
In this paper, we propose a new method, CAUSAL-Imp, which can impute the association statistics at untyped variants while taking into account variants in the ...
In this paper, we propose a new method, CAUSAL-Imp, which can impute the association statistics at untyped variants while taking into account variants in the ...
It is shown that traditional imputation approaches underestimate the association statistics for variants involved in the trait, and the results demonstrate ...
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Apr 12, 2017 · Imputation allows geneticists to study variants that have not been directly genotyped in a sample and thereby to increase power and resolution ...
Genotype imputation has been widely utilized for two reasons in the analysis of genome-wide association studies (GWAS). One reason is to increase the power ...
Nov 23, 2022 · In this paper, we propose an efficient knockoff-based method, GhostKnockoff, for genome-wide association studies (GWAS) that leads to improved ...